Dexamethasone and Etoricoxib for Pain Prevention Following Periodontal Surgery

NCT ID: NCT00970112

Last Updated: 2010-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-11-30

Study Completion Date

2010-03-31

Brief Summary

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The purpose of this study is to investigate whether preemptive medication with dexamethasone or etoricoxib provides better pain management and control than placebo following periodontal surgery.

Detailed Description

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Conditions

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Pain Control

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Placebo

Placebo 1 hour before surgery

Group Type PLACEBO_COMPARATOR

Open Flap Debridement

Intervention Type PROCEDURE

Open flap debridement - access flap + scaling and root planning

Etoricoxib

Etoricoxib 1 hour before surgery

Group Type EXPERIMENTAL

Open Flap Debridement

Intervention Type PROCEDURE

Open flap debridement - access flap + scaling and root planning

Dexamethaone

Dexamethasone 1 hour before surgery

Group Type EXPERIMENTAL

Open Flap Debridement

Intervention Type PROCEDURE

Open flap debridement - access flap + scaling and root planning

Interventions

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Open Flap Debridement

Open flap debridement - access flap + scaling and root planning

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients presenting moderate or severe periodontitis after nonsurgical periodontal treatment with clinical signs of inflammation

Exclusion Criteria

* Pregnant
* Diabetes mellitus
* Heart diseases
* Allergic to components of the medications
* Risk of endocarditis
Minimum Eligible Age

20 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidade Estadual de Ponta Grossa

OTHER

Sponsor Role lead

Responsible Party

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UEPG

Principal Investigators

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João Paulo Steffens, MSc Student

Role: PRINCIPAL_INVESTIGATOR

UEPG

Fábio André Santos, PhD

Role: STUDY_DIRECTOR

UEPG

Gibson Luiz Pilatti, PhD

Role: STUDY_CHAIR

UEPG

Locations

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UEPG

Ponta Grossa, Paraná, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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51/2008

Identifier Type: -

Identifier Source: secondary_id

08169/08

Identifier Type: -

Identifier Source: org_study_id

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