A Randomized, Double Blind, Placebo-controlled Study to Assess the the Preemptive Benefit of Etoricoxib in Patients Receiving Anterior Cruciate Ligament Reconstruction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-05-31

Study Completion Date

2010-06-30

Brief Summary

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Post surgical pain associated with ligament reconstruction may persist for few days after the surgical procedure. Arcoxia is a new anti-inflammatory and analgesic drug that alleviate pain through oral administration. This study will test the safety and efficacy of Arcoxia in the management of post-operational pain in patients receive the ligament reconstruction surgery.

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Detailed Description

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Conditions

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Post-operational Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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1

Etoricoxib 90mg

Group Type ACTIVE_COMPARATOR

Arcoxia(etoricoxib 90 mg/tablet)

Intervention Type DRUG

Arcoxia(etoricoxib 90 mg/tablet) or placebo, #1, 3 days

2

placebo

Group Type PLACEBO_COMPARATOR

Arcoxia(etoricoxib 90 mg/tablet)

Intervention Type DRUG

Arcoxia(etoricoxib 90 mg/tablet) or placebo, #1, 3 days

Interventions

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Arcoxia(etoricoxib 90 mg/tablet)

Arcoxia(etoricoxib 90 mg/tablet) or placebo, #1, 3 days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Men and women age ranged from 16\~35 who have anterior cruciate ligament injury and/or associated injuries are scheduled for ACL reconstruction surgery.
2. Patient agrees to participate into this study and is willing to sign the patient informed consent form.

Minimum Eligible Age

16 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No