"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up

NCT ID: NCT00960817

Last Updated: 2009-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

EARLY_PHASE1

Study Classification

INTERVENTIONAL

Brief Summary

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The investigators will investigate patients undergoing coronary angiography with normal coronary but slow blood flow that was normalized after adenosine injection into the coronary artery. The investigators believe that they have small vessel coronary disease which is the initial presentation of coronary disease prior to anatomical narrowing. To alleviate this phenomenon the investigators intend to examine the long-term clinical response of these patients to treatment with dipyridamole, a well-known medication with almost no side-effects that increases the level of adenosine in the tissue.

Detailed Description

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Conditions

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Coronary Angiography

Study Groups

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1. Routine treatment

Control group

Group Type ACTIVE_COMPARATOR

Statin, aspirin

Intervention Type DRUG

2. Dipyridamole treatment

Group that receives Dipyridamole treatment

Group Type EXPERIMENTAL

Dipyridamole

Intervention Type DRUG

Interventions

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Statin, aspirin

Intervention Type DRUG

Dipyridamole

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing coronary angiography and who have normal coronary artery with slow blood flow that normalized with adenosine injection into the coronary artery

Exclusion Criteria

* Significant coronary disease
* Unstable patients
* Patients with known sensitivity to dipyridamole
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hillel Yaffe Medical Center

OTHER_GOV

Sponsor Role lead

Responsible Party

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Hillel Yaffe Medical Center

Locations

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Hillel Yaffe Medical Center

Hadera, , Israel

Site Status

Countries

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Israel

Other Identifiers

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HYMC 02/2009

Identifier Type: -

Identifier Source: org_study_id

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