Accolade® TMZF® Hip Stem Outcomes Study

NCT ID: NCT00957658

Last Updated: 2017-08-14

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

241 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-31

Study Completion Date

2014-05-31

Brief Summary

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The purpose of this study is to evaluate clinical and radiographic outcome data in patients implanted with the Accolade® TMZF® femoral stem.

Detailed Description

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A prospective, post-market, multi-centered clinical evaluation of the Accolade® TMZF® hip stem device. All patients enrolled will receive the study device. All study patients will undergo a preoperative central Dual energy X-ray absorptiometry (DXA) scan to determine bone mineral density (BMD) values.

Conditions

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Arthroplasty, Replacement, Hip

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Accolade® TMZF® Hip Stem

Accolade® TMZF® Hip Stem Study Device

Group Type OTHER

Accolade® TMZF® Hip Stem

Intervention Type DEVICE

Accolade® TMZF® Hip Stem

Interventions

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Accolade® TMZF® Hip Stem

Accolade® TMZF® Hip Stem

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patient is a candidate for a primary total hip replacement.
2. Patient has primary diagnosis of osteoarthritis (OA).
3. Male and non-pregnant female patients ages 18 to 90.
4. Patient has signed an Institutional Review Board (IRB) approved, study specific Informed Patient Consent Form.
5. Patient willing and able to comply with postoperative scheduled clinical and radiographic evaluations and rehabilitation.
6. Patient capable of undergoing a pre-op central DXA (dual-energy x-ray absorptiometry) scan for a bone mineral density (BMD) reading.

Exclusion Criteria

1. Patient has an active infection within the affected hip joint.
2. Patient requires a revision surgery of a previously implanted total hip arthroplasty or hip fusion to the affected joint.
3. Patient who is morbidly obese, Body Mass Index (BMI) \> 40.
4. Patient has a neuromuscular or neurosensory deficiency, which limits ability to evaluate the safety and efficacy of the device.
5. Patient has the following diagnosed systemic diseases: Paget's disease, renal osteodystrophy, lupus erythematosus, rheumatoid arthritis, metabolic bone disease and sickle cell anemia.
6. Patient is immunologically suppressed or receiving chronic steroids more than 30 days. Patients receiving oral or IV steroids within one month of surgery.
7. Patient is a prisoner.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stryker Orthopaedics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Krushell, MD

Role: STUDY_CHAIR

Baystate Medical Center

Carlton Savory, MD

Role: PRINCIPAL_INVESTIGATOR

Hughston Sports Medicine Center

Robert Zann, MD

Role: PRINCIPAL_INVESTIGATOR

Boca Raton Community Hospital

Steven Gausewitz, MD

Role: PRINCIPAL_INVESTIGATOR

Hoag Hospital

R. Scott Oliver, MD

Role: PRINCIPAL_INVESTIGATOR

Jordan Hospital

Mary O'Connor, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Anthony Sanchez, MD

Role: PRINCIPAL_INVESTIGATOR

Spartanburg Regional Health Service District, Inc

Mark Visk, MD

Role: PRINCIPAL_INVESTIGATOR

Spartanburg Regional Health Service District, Inc

Steven Teeny, MD

Role: PRINCIPAL_INVESTIGATOR

St. Clare Hospital

Alan Valadie, MD

Role: PRINCIPAL_INVESTIGATOR

Coastal Orthopedics and Sports Medicine

Steven Zelicof, MD

Role: PRINCIPAL_INVESTIGATOR

Sound Shore Medical Center of Westchester

James Bates, MD

Role: PRINCIPAL_INVESTIGATOR

Alvarado Hospital

Locations

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Newport Orthopaedic Institute

Newport Beach, California, United States

Site Status

Alvarado Ortho Medical Group

San Diego, California, United States

Site Status

Orthopaedic Surgery Associates

Boynton Beach, Florida, United States

Site Status

Coastal Orthopaedics

Bradenton, Florida, United States

Site Status

Mayo Clinic Jacksonville

Jacksonville, Florida, United States

Site Status

Hughston Clinic P.A.

Columbus, Georgia, United States

Site Status

Plymouth Bay Ortho Association

Duxbury, Massachusetts, United States

Site Status

New England Orthopaedic Surgeons

Springfield, Massachusetts, United States

Site Status

Specialty Orthopaedics

Harrison, New York, United States

Site Status

Spartanburg Regional Medical Center

Spartanburg, South Carolina, United States

Site Status

Northwest Orthopaedic Institute

Tacoma, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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59

Identifier Type: -

Identifier Source: org_study_id

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