Oral Language in Children With Down Syndrome

NCT ID: NCT00952354

Last Updated: 2009-08-06

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2007-08-31
• Study Completion Date: 2009-08-31

Brief Summary

The objective of this research is to verify the language of children with Down syndrome concerning lexical, syntactic and semantic aspects using MLU. The hypothesis is that children with Down syndrome will present low performance, regarding not only the quantitative measures as MLU-m, MLU-w, GM-1 and GM-2, but also regarding the qualitative aspects of their production, when compared to children with typical development.

Detailed Description

One of the alternatives to observe and assess language development and language disorders is to analyze spontaneous language samples, which allos the identification of qualitative and quantitative aspects. The analysis involves the MLU-morphemes, MLU-words and words classes. All words produced are analyzed, including interjections, adverbs and adjectives.Word classes with grammatical characteristics present lower averages, as prepositions and conjunctions. Reference parameters are the ones of the spoken language. The objective assessment with qualitative and quantitative data may help the speech and language pathologist/therapist to determine therapeutic guidelines to each patient.

Conditions

Down Syndrome

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

research group

60 children aged from 3 to 10 years, both genders, observed in a symbolic play situation with their language therapists

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• genetic diagnosis of Down syndrome
• good health conditions
• normal results on audiologic evaluation
• pediatric and ear, nose and throat periodic check ups.
• attend speech-language therapy at the Speech Language Pathology Laboratory in Syndromes and Sensorimotor Deficits (SLPL-SSD) of the School of Medicine of the University of São Paulo.

Exclusion Criteria

• submission to long term hospitalizations due to heart diseases and major respiratory airway infections, that may interfere in the child's global development
• presence of visual or auditory important deficits

• Minimum Eligible Age: 3 Years
• Maximum Eligible Age: 10 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Conselho Nacional de Desenvolvimento Científico e Tecnológico

OTHER_GOV

Sponsor Role: collaborator

University of Sao Paulo

OTHER

Sponsor Role: lead

Responsible Party

University of São Paulo

Principal Investigators

Suelly CO Limongi, PhD

Role: STUDY_CHAIR

University of Sao Paulo

Rosangela V Andrade, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Fabiola C Flabiano, PhD student

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Porto Eliza, Ms student

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Angela MA Carvalho, Ms student

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

University of Sao Paulo - School of Medicine - Department of Physiotherapy, Communication Sciences and Disorders, Occupational Therapy

São Paulo, São Paulo, Brazil

Countries

Brazil

References

Limongi SC, Oliveira Ede F, Ienne LM, Andrade RV, Carvalho AM. The use of nouns and verbs by children with Down syndrome in two different situations. Codas. 2013;25(3):262-7. doi: 10.1590/s2317-17822013000300012. English, Portuguese.

Reference Type: DERIVED

PMID: 24408338 (View on PubMed)

Marques SF, Limongi SC. [Mean length utterance (MLU) as a measure of language development of children with Down syndrome]. J Soc Bras Fonoaudiol. 2011;23(2):152-7. doi: 10.1590/s2179-64912011000200012. Portuguese.

Reference Type: DERIVED

PMID: 21829931 (View on PubMed)

Other Identifiers

CNPq-473492/2007-5

Identifier Type: -

Identifier Source: secondary_id

473492/2007-5

Identifier Type: -

Identifier Source: org_study_id