nContactSurgical Numeris-AF Tethered Coagulation System for Treatment of Persistent & LSP AF

NCT ID: NCT00950092

Last Updated: 2014-04-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-10-31

Study Completion Date

2013-10-31

Brief Summary

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This is a multi center, non-randomized, prospective, open label, clinical trial evaluating the safety and efficacy of the nContact Surgical Numeris-AF Tethered Coagulation System when used to treat patients with persistent and longstanding persistent AF during concomitant cardiac surgery.

Detailed Description

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The purpose of this study is to determine the safety and efficacy of the Numeris-AF Tethered Coagulation System with VisiTrax when used to treat persistent and longstanding persistent Atrial Fibrillation(AF)during concomitant cardiac surgery.

Conditions

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Atrial Fibrillation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treatment

Group Type OTHER

Numeris-AF Tethered Coagulation System with VisiTrax

Intervention Type DEVICE

Surgical radiofrequency (RF) epicardial ablation using the nContact Numeris-AF Tethered Coagulation System

Interventions

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Numeris-AF Tethered Coagulation System with VisiTrax

Surgical radiofrequency (RF) epicardial ablation using the nContact Numeris-AF Tethered Coagulation System

Intervention Type DEVICE

Other Intervention Names

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RF Ablation Coagulation of cardiac tissue nContact Surgical

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years; \< 80 years
* Left atrium =\< 6.0 cm
* Documented persistent or longstanding persistent AF
* History of AF =\< 10 years
* Scheduled for a concomitant cardiac procedure

* Coronary bypass surgery (CABG)
* Mitral valve repair/replacement
* Aortic valve replacement
* ASD repair
* Tricuspid valve repair/replacement
* Myxoma
* Any combination of the above procedures
* Provided written informed consent

Exclusion Criteria

* Left atrial size \> 6.0 cm (pre-op TTE - parasternal 4 chamber view)
* History of AF \> 10 years
* Left ventricular ejection fraction \< 30%
* Pregnant or planning to become pregnant during study
* Co-morbid medical conditions that limit one year life expectancy
* History of coagulopathy
* Patients who are contraindicated for anticoagulants(heparin, warfarin etc.)
* Previous cardiac surgery
* History of pericarditis
* Previous cerebrovascular accident (CVA)
* Patients who have active infection or sepsis
* Patients who have uncorrected reversible cause(s) of AF such as hyperthyroidism and electrolyte imbalance
* Patients who are being treated for ventricular arrhythmias
* Patients who have had a previous catheter ablation for AF (does not include ablation for Aflutter)
* Current participation in another clinical investigation of a medical device or a drug, or recent participation in such a study within 30 days prior to study enrollment.
* Not competent to legally represent him or herself (e.g., requires a guardian or caretaker as a legal representative).
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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nContact Surgical Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Edward Garrett, M.D.

Role: PRINCIPAL_INVESTIGATOR

Baptist Memorial Hospital - Memphis

Locations

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Venice Regional Medical Center

Venice, Florida, United States

Site Status

Baptist Memorial Hospital

Memphis, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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VAL-1116(C)

Identifier Type: -

Identifier Source: org_study_id

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