DECIDE-HF: Heart Rate Variability in Heart Failure Patients

NCT ID: NCT00949676

Last Updated: 2013-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2013-12-31

Brief Summary

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The purpose of this study is to determine whether heart rate variability-like parameters are related to changes in the disease status of a subject that suffers from a disease that decreases the pumping function of the heart.

Detailed Description

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Conditions

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Systolic Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Heart Failure

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Subject has signed and dated the study-specific informed consent form
* Subject is 18 years of age or older
* Subject is expected to remain available for follow-ups
* Subject is able and willing to comply with the protocol requirements
* Subject has predominant Normal Sinus Rhythm
* Subject has systolic Heart Failure and is at the moment of enrollment in NYHA class II or III and has an ejection fraction of less then 40%
* Subject has had a HF-related hospitalization in the past 12 months

Exclusion Criteria

* Subject needs permanent atrial pacing (\> 10%)
* Subject has intermittent 2nd or intermittent 3rd degree block
* Subject has persistent or permanent AF
* Subject has Long QT syndrome, Brugada syndrome, Jervell and Lange- Nielsen syndrome, Romano-Ward syndrome, Andersen-Tawil syndrome or Timothy's syndrome
* Subject has had recent (\<2 months) acute coronary syndrome
* Subject has had recent (\<2 months) revascularization
* Subject has a pending cardiac transplant or revascularization
* Subject has severe stenotic valvular heart disease
* Subject has severe pulmonary (forced expiratory volume in 1 s \< 1 L) hepatic or renal (plasma creatinine \> 0.2 mmol/L) disease
* Subject is participating in another study that may affect the results of this study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic BRC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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DECIDE HF Team

Role: STUDY_CHAIR

Medtronic BRC

Locations

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Antwerp, , Belgium

Site Status

Kiel, , Germany

Site Status

Munich, , Germany

Site Status

Tübingen, , Germany

Site Status

Leeds, , United Kingdom

Site Status

Countries

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Netherlands Belgium Germany United Kingdom

Other Identifiers

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DECIDE-HF

Identifier Type: -

Identifier Source: org_study_id