US Cycle Control and Blood Pressure Study

NCT ID: NCT00920985

Last Updated: 2015-10-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

346 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2010-09-30

Brief Summary

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Birth Control Patch Study

Detailed Description

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Conditions

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Contraception

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Gestodene/EE (FC Patch Low, BAY86-5016)

Intervention Type DRUG

21-day regimen per cycle (1 patch a week for 3 weeks followed by a 7-day patch-free period) for 7 cycles and placebo tablets matching the conditions of the treatment of Arm 2

Arm 2

Group Type ACTIVE_COMPARATOR

Oral contraceptive (equivalent to the active treatment tablets of Levlite), 21-day blister SH D00593A

Intervention Type DRUG

21-day regimen per cycle (1 tablet a day for 3 weeks followed by a 7-day tablet-free period) for 7 cycles and placebo patches matching the conditions of the treatment of Arm 1

Interventions

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Gestodene/EE (FC Patch Low, BAY86-5016)

21-day regimen per cycle (1 patch a week for 3 weeks followed by a 7-day patch-free period) for 7 cycles and placebo tablets matching the conditions of the treatment of Arm 2

Intervention Type DRUG

Oral contraceptive (equivalent to the active treatment tablets of Levlite), 21-day blister SH D00593A

21-day regimen per cycle (1 tablet a day for 3 weeks followed by a 7-day tablet-free period) for 7 cycles and placebo patches matching the conditions of the treatment of Arm 1

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Female subject requesting contraception
* Age: 18 - 45 years (inclusive); smokers must not be older than 35 years at the time of informed consent
* Normal cervical smear not requiring further follow-up (a cervical smear has to be taken at screening visit or a normal result has to be documented within the previous 6 months)
* History of regular cyclic menstrual periods

Exclusion Criteria

* Pregnancy or lactation
* Significant skin reaction to transdermal preparations or sensitivity to surgical / medical tape
* Any disease that may worsen under hormonal treatment (cardiovascular, liver, metabolic)
* Use of other contraceptive methods than study medication
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Chandler, Arizona, United States

Site Status

Glendale, Arizona, United States

Site Status

Phoenix, Arizona, United States

Site Status

Tucson, Arizona, United States

Site Status

Anaheim, California, United States

Site Status

San Diego, California, United States

Site Status

Clearwater, Florida, United States

Site Status

Daytona Beach, Florida, United States

Site Status

Lake Worth, Florida, United States

Site Status

Leesburg, Florida, United States

Site Status

Miami, Florida, United States

Site Status

Atlanta, Georgia, United States

Site Status

Decatur, Georgia, United States

Site Status

Metairie, Louisiana, United States

Site Status

Kalamazoo, Michigan, United States

Site Status

St Louis, Missouri, United States

Site Status

Las Vegas, Nevada, United States

Site Status

New Brunswick, New Jersey, United States

Site Status

Winston-Salem, North Carolina, United States

Site Status

Cincinnati, Ohio, United States

Site Status

Philadelphia, Pennsylvania, United States

Site Status

Pittsburgh, Pennsylvania, United States

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Wexford, Pennsylvania, United States

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Columbia, South Carolina, United States

Site Status

Richmond, Virginia, United States

Site Status

Renton, Washington, United States

Site Status

Seattle, Washington, United States

Site Status

La Crosse, Wisconsin, United States

Site Status

Countries

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United States

References

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Merz M, Kroll R, Lynen R, Bangerter K. Bleeding pattern and cycle control of a low-dose transdermal contraceptive patch compared with a combined oral contraceptive: a randomized study. Contraception. 2015 Feb;91(2):113-20. doi: 10.1016/j.contraception.2014.10.004. Epub 2014 Oct 13.

Reference Type DERIVED
PMID: 25453585 (View on PubMed)

Other Identifiers

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91556

Identifier Type: -

Identifier Source: org_study_id

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