Birth Control Patch Study

NCT ID: NCT00984789

Last Updated: 2014-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

393 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-31

Study Completion Date

2010-09-30

Brief Summary

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400 healthy women needed contraception will be asked to participate in this study. Half will be given EVRA, half will be given FC Patch low. They will be expected to apply the patches for 21 days of their cycle, for 7 cycles in total. The study will compare the patterns of menstrual bleeding on these two treatments, plus how effective they are at preventing pregnancy, general safety, and their acceptability to the participants.

Detailed Description

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Conditions

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Contraception

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Ethinylestradiol/Gestodene (FC Patch Low BAY86-5016)

Intervention Type DRUG

0.55mg ethinylestradiol and 2.1mg gestodene

Arm 2

Group Type ACTIVE_COMPARATOR

Norelgestromin/Ethinylestradiol (EVRA)

Intervention Type DRUG

0.6mg ethinylestradiol and 6mg norelgestromin

Interventions

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Ethinylestradiol/Gestodene (FC Patch Low BAY86-5016)

0.55mg ethinylestradiol and 2.1mg gestodene

Intervention Type DRUG

Norelgestromin/Ethinylestradiol (EVRA)

0.6mg ethinylestradiol and 6mg norelgestromin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy women requesting contraception aged 18-35 years old
* Smokers must not be older than 30 at time of informed consent
* History of regular cyclic menstrual periods, normal cervical smear

Exclusion Criteria

* Pregnancy or lactation
* Obesity (BMI\>30), hypersensitivity to any ingredients of the study drug, significant skin reaction to transdermal preparations, any diseases/conditions that can compromise the functions of the body system (resulting in altered absorption/accumulation/ metabolism/excretion of the study drug), any diseases / conditions that may worsen under hormonal treatment
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Parexel

INDUSTRY

Sponsor Role collaborator

Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Mödling, Lower Austria, Austria

Site Status

Wiener Neustadt, Lower Austria, Austria

Site Status

Graz, Styria, Austria

Site Status

Wörgl, Tyrol, Austria

Site Status

Bregenz, Vorarlberg, Austria

Site Status

Graz, , Austria

Site Status

Innsbruck, , Austria

Site Status

Vienna, , Austria

Site Status

Vienna, , Austria

Site Status

Zeltweg, , Austria

Site Status

Brno, , Czechia

Site Status

České Budějovice, , Czechia

Site Status

Hradec Králové, , Czechia

Site Status

Olomouc, , Czechia

Site Status

Písek, , Czechia

Site Status

Prague, , Czechia

Site Status

Prague, , Czechia

Site Status

Prague, , Czechia

Site Status

Prague, , Czechia

Site Status

De Bilt, , Netherlands

Site Status

Den Helder, , Netherlands

Site Status

Heerlen, , Netherlands

Site Status

Nijmegen, , Netherlands

Site Status

Countries

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Austria Czechia Netherlands

References

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Gruber D, Skrivanek A, Serrani M, Lanius V, Merz M. A comparison of bleeding patterns and cycle control using two transdermal contraceptive systems: a multicenter, open-label, randomized study. Contraception. 2015 Feb;91(2):105-12. doi: 10.1016/j.contraception.2014.10.003. Epub 2014 Oct 13.

Reference Type DERIVED
PMID: 25453582 (View on PubMed)

Other Identifiers

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2008-007308-27

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

13082

Identifier Type: -

Identifier Source: org_study_id

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