Study Evaluating Levonorgestrel and Ethinyl Estradiol for Oral Contraception

NCT ID: NCT02021097

Last Updated: 2013-12-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

1008 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2016-02-29

Brief Summary

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The purpose of this study is to evaluate the contraceptive efficacy and safety of an oral contraceptive containing a combination of LNG 100mcg/EE 20mcg compared to LNG 150mcg/EE 30 mcg.

Detailed Description

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Conditions

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Oral Contraceptive

Keywords

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Levonorgestrel; Ethinyl Estradiol; Oral Contraceptive

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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LNG100 mcg/EE20 mcg

Group Type EXPERIMENTAL

Levonorgestrel 100 mcg and Ethinyl Estradiol 20 mcg

Intervention Type DRUG

Tablet, orally, opd

LNG 150mcg/ EE 30mcg

Group Type ACTIVE_COMPARATOR

Levonorgestrel 150 mcg and Ethinyl Estradiol 30 mcg

Intervention Type DRUG

Tablet, orally, opd

Interventions

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Levonorgestrel 100 mcg and Ethinyl Estradiol 20 mcg

Tablet, orally, opd

Intervention Type DRUG

Levonorgestrel 150 mcg and Ethinyl Estradiol 30 mcg

Tablet, orally, opd

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy women,aged 20-35 years who wish to use a contraceptive.
* Women without reproductive system infection complications.
* Willingness to not use other forms of hormonal treatment.
* Three regular menstrual cycles before the study(21-35 days per cycle with 3-7 day's bleeding period, without amenorrhea or irregular bleeding).
* Signed informed consent prior to entry into the trial.

Exclusion Criteria

* Any contraindication to the use of oral contraceptives.
* Vascular, metabolic, hepatic, renal, oncologic and other diseases.
Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Regenex Pharmaceutical, China

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Chengliang Xiong, Dr

Role: PRINCIPAL_INVESTIGATOR

Family Planning Research Institute of TJMC,HUST

Locations

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Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Guangzhou, Guangdong, China

Site Status RECRUITING

Shantou, Guangdong, China

Site Status RECRUITING

Zhongshan, Guangdong, China

Site Status RECRUITING

Guiyang, Guizhou, China

Site Status RECRUITING

Guiyang, Guizhou, China

Site Status RECRUITING

Wuhan, Hubei, China

Site Status RECRUITING

Changde, Hunan, China

Site Status RECRUITING

Changsha, Hunan, China

Site Status RECRUITING

Nanjing, Jiangsu, China

Site Status RECRUITING

Nanjing, Jiangsu, China

Site Status RECRUITING

Yangzhou, Jiangsu, China

Site Status RECRUITING

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Taiyuan, Shanxi, China

Site Status RECRUITING

Xi’an, Shanxi, China

Site Status RECRUITING

Tianjin, Tianjin Municipality, China

Site Status RECRUITING

Ürümqi, Xinjiang, China

Site Status RECRUITING

Taizhou, Zhejiang, China

Site Status NOT_YET_RECRUITING

Countries

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China

Central Contacts

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Chengliang Xiong, Dr

Role: CONTACT

Email: [email protected]

Other Identifiers

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RH-ZQ-03RCT

Identifier Type: -

Identifier Source: org_study_id