Study of ADAMTS-13 Activity, Von Willebrand Factor and Platelet-Monocyte Aggregation in Coronary Artery Disease

NCT ID: NCT00905294

Last Updated: 2013-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

11 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-08-31

Study Completion Date

2010-08-31

Brief Summary

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The purpose of this research is to determine the relationship between proteins and enzymes in the blood and how they work with platelets to form blood clots in patients with coronary artery disease. The investigators hypothesize that the relationship between these factors could potentially be useful in identifying patients at higher risk for heart attacks.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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coronary artery disease

Subjects with coronary artery disease undergoing percutaneous coronary intervention

Blood draws

Intervention Type OTHER

Observational: blood draws only

Interventions

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Blood draws

Observational: blood draws only

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Admission to hospital with suspected index event of Non-ST-Elevation Myocardial Infarction (NSTEMI), Unstable Angina (UA) or Stable Angina (SA)
* Planned percutaneous coronary intervention during admission

Exclusion Criteria

* Recent history (\< 6 months) of an acute coronary syndrome (other than current admission) or stroke
* Recent history (\< 6 months) of major surgery, trauma or thromboembolic event
* Percutaneous coronary or peripheral intervention or any stent placement performed within the past 6 months
* Current evidence of infection
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Royal College of Surgeons, Ireland

OTHER

Sponsor Role collaborator

University College Cork

OTHER

Sponsor Role lead

Responsible Party

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Professor Noel Caplice

Professor, Cardiovascular Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Noel M. Caplice, M.D, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University College Cork, Ireland

Dermot Kenny, M.D.

Role: STUDY_DIRECTOR

Royal College Surgeons in Ireland

David Foley, M.B.

Role: STUDY_DIRECTOR

Beaumont Hospital, Dublin, Ireland

Locations

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Cork University Hospital

Cork, , Ireland

Site Status

Beaumont Hospital

Dublin, , Ireland

Site Status

Countries

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Ireland

Other Identifiers

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INFACTs 2009-001

Identifier Type: -

Identifier Source: org_study_id

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