Duplex Guided Application of Local Anesthetic Before Femoral Artery Catheterization

NCT ID: NCT00903825

Last Updated: 2010-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-01-31

Study Completion Date

2010-01-31

Brief Summary

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The aim of this study is to evaluate the optimization of local anesthetic effect with duplex ultrasound-guided injection of lidocaine before femoral artery puncture during diagnostic or therapeutic interventional procedures.

In total, 200 patients scheduled for various diagnostic or therapeutic interventional radiology procedures requiring femoral artery puncture, will be randomized in two groups after informed consent. Patients will be randomized to undergo groin local anesthesia with the proposed method of duplex ultrasound guided injection of lidocaine versus standard injection of lidocaine with manual palpation (control group).

The protocol includes the registration of patients' demographics (age, gender, risk factors for peripheral arterial disease), arterial morphological characteristics (calcifications and presence of atheromatous disease), as well as technical details of the procedure (total puncture duration, sheath size, antegrade/retrograde puncture, etc.)

Primary study endpoint will be peri-procedural pain that will be assessed with the use of a visual analog scale (VAS) completed by the patient at the end of the procedure. Secondary study endpoints will evaluate procedural safety and complications during the immediate post-procedural period (up to 7 days).

Detailed Description

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Conditions

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Local Anesthetics Ultrasound Guidance Catheterization

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Manual palpation

Local anesthetic before femoral artery puncture will be injected with the classic manual palpation technique

Group Type ACTIVE_COMPARATOR

Injection of femoral local anesthetic (lidocaine) with manual palpation

Intervention Type PROCEDURE

Injection of lidocaine before femoral artery catheterization with manual palpation.

Ultrasound guidance

Local anesthetic before femoral artery puncture will be performed with the use of duplex ultrasound guidance

Group Type EXPERIMENTAL

Ultrasound guided injection of femoral local anesthetic (lidocaine)

Intervention Type PROCEDURE

Injection of lidocaine (\< 10 mls of lidocaine, 1%w/v) before femoral artery puncture with free-hand duplex ultrasound guidance.

Interventions

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Ultrasound guided injection of femoral local anesthetic (lidocaine)

Injection of lidocaine (\< 10 mls of lidocaine, 1%w/v) before femoral artery puncture with free-hand duplex ultrasound guidance.

Intervention Type PROCEDURE

Injection of femoral local anesthetic (lidocaine) with manual palpation

Injection of lidocaine before femoral artery catheterization with manual palpation.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient scheduled for diagnostic intra-arterial procedures
* Patient scheduled for therapeutic intra-arterial procedures
* At least 1 palpable femoral artery
* Patient informed consent

Exclusion Criteria

* Allergic reaction to iodine contrast media
* Allergic reaction to lidocaine
* Bilateral obstruction of femoral arteries
* Impaired or lost vision
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Patras

OTHER

Sponsor Role lead

Responsible Party

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Patras University Hospital

Principal Investigators

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Dimitris Siablis, Professor

Role: STUDY_DIRECTOR

Department of Radiology, Patras University Hospital

Locations

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Department of Radiology, Angiography Suite, Patras University Hospital

Pátrai, ACHAIA, Greece

Site Status

Countries

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Greece

Other Identifiers

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11/14.4.2009

Identifier Type: -

Identifier Source: secondary_id

44/27-2-09

Identifier Type: -

Identifier Source: org_study_id

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