Green Tea, High in Epigallocatechin Gallate (EGCG) and Postprandial Fat Oxidation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-10-31

Study Completion Date

2009-05-31

Brief Summary

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The body of evidence regarding the health benefits of green tea has grown considerably during the last decade and includes antioxidant properties, anti- cancer, anti-obesity and anti-diabetes effects. There has been evidence that green tea extract favorably affect body weight and body fat and has positive effects on blood glucose control

Aim of this study is to investigate the short term effect (3-day)of TEAVIGO (high in the catechin EGCG) on postprandial fat oxidation during different phases of the postprandial period in overweight subjects. Secondly, in a subset of volunteers changes in lipolysis and glucose metabolism will be studied in skeletal muscle and adipose tissue.

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Detailed Description

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Conditions

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Obesity Type 2 Diabetes Mellitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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EGCG

Double blind randomized, placebo-controlled cross-over design with two arms:

* the green tea extract TEAVIGO, high in EGCG and
* placebo

Group Type EXPERIMENTAL

Effect of the green tea extract TEAVIGO, high in EGCG, on postprandial fat oxidation

Intervention Type DIETARY_SUPPLEMENT

green tea extract TEAVIGO, high in EGCG

placebo

Group Type PLACEBO_COMPARATOR

Effect of the green tea extract TEAVIGO, high in EGCG, on postprandial fat oxidation

Intervention Type DIETARY_SUPPLEMENT

green tea extract TEAVIGO, high in EGCG

Interventions

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Effect of the green tea extract TEAVIGO, high in EGCG, on postprandial fat oxidation

green tea extract TEAVIGO, high in EGCG

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age between 20 and 50 y
* BMI 25.0-29.9 kg/m2
* Normal fasting glucose \<6.1 mmol/L
* Blood pressure (systolic blood pressure 100-150 mmHg, diastolic blood pressure 60-90 mmHg)
* Weight stable in last 3 months (±2 kg)

Exclusion Criteria

* pregnant, lactating or (post)menopausal women
* regular smokers
* people with intensive fitness training eg athletes
* habitual consumption of green or black tea (more than 1 or 2 cups a day, respectively)
* not more than 300 mg/day caffeine consumption

Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes