Evaluation of Adhexil Safety and Efficacy in Prevention and/or Reduction of Adhesions in Gynecological Surgery

NCT ID: NCT00865488

Last Updated: 2009-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

SUSPENDED

Clinical Phase

PHASE3

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-31

Study Completion Date

2010-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective of this study is to evaluate the safety and efficacy of ADHEXIL™ in preventing and/or reducing post-operative adhesions in patients undergoing surgery involving the ovaries.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Patients will be divided into two arms: 1) patients who will be treated in accordance with standard of care; 2) patients for which ADHEXIL™ will be applied on one ovary and fallopian tube.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Ovarian Cysts Endometriosis Adhesions

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1

patients who will be treated in accordance with standard of care

Group Type NO_INTERVENTION

No interventions assigned to this group

2

patients for which Adhexil will be applied to prevent/reduce adhesions

Group Type EXPERIMENTAL

ADHEXIL

Intervention Type BIOLOGICAL

Adhesions prevention

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

ADHEXIL

Adhesions prevention

Intervention Type BIOLOGICAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Female patients aged 18-45 years at screening.
* Patients undergoing elective laparoscopic surgery involving at least one adnexa.

Exclusion Criteria

* Pregnant (including ectopic pregnancy) or breastfeeding patient.
* Patients with a documented diagnosis of cancer.
* Patients with a lymphatic, hematologic or coagulation disorder.
* Patients with a known or suspected hypersensitivity to blood, blood products or any constituent of Adhexil™.
* Patients who are immunocompromised, possess autoimmune disorders, or who are routinely taking anticoagulants.
* Patients who have participated in another clinical study within 30 days of enrolment.
* Investigator's opinion that the patient is medically unfit or would be at major risk if enrolled into the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

OMRIX Biopharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Omrix Biopharmaceuticals Ltd.

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Eran Kurman, B.med.Sc, MBA

Role: STUDY_CHAIR

OMRIX Biopharmaceuticals

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Richmond, Virginia, United States

Site Status

Duisburg, , Germany

Site Status

Mexico City, , Mexico

Site Status

Moscow, , Russia

Site Status

Valencia, , Spain

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States Germany Mexico Russia Spain

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

AA-GYN-002

Identifier Type: -

Identifier Source: org_study_id