Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
PHASE3
50 participants
INTERVENTIONAL
2009-02-28
2012-01-31
Brief Summary
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Detailed Description
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* After basic examinations and hydration, the women will randomized to thiamine or promethazine treatment.
* If no improvement is shown, the patient will be treated with the other drug
* The patients will be interviewed on their current visit and every two weeks until 14th week of gestation
* The interview includes medical history and details about their illness, other treatments, hospitalization etc.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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1. thiamine
Pregnant women until 12 week of gestation who refer to the ER because of nausea and vomiting and didn't improve after hydration, will receive thiamine IV
thiamine & promethazine
thiamine 100 mg IV promethazine 25 mg IV
2. promethazine
Pregnant women until 12 week of gestation who refer to the ER because of nausea and vomiting and didn't improve after hydration, will receive promethazine IV
thiamine & promethazine
thiamine 100 mg IV promethazine 25 mg IV
Interventions
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thiamine & promethazine
thiamine 100 mg IV promethazine 25 mg IV
Eligibility Criteria
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Inclusion Criteria
* The women visit the ER because of nausea and vomiting
* The women didn't received thiamine yet
Exclusion Criteria
* Women that received thiamine before
* women that allergic to the studied drugs
18 Years
FEMALE
No
Sponsors
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HaEmek Medical Center, Israel
OTHER
Responsible Party
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Principal Investigators
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Yfat Kadan
Role: PRINCIPAL_INVESTIGATOR
haemek medical center
Locations
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Gynecologic department, Haemek medical center
Afula, , Israel
Countries
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Other Identifiers
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0101-08-EMC
Identifier Type: -
Identifier Source: org_study_id
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