The Standard Concentration of Morphine as a Positive Control for Intradermal Skin Test

NCT ID: NCT00853476

Last Updated: 2011-02-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-03-31

Study Completion Date

2009-10-31

Brief Summary

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This study aims to compare skin reactivity results between morphine and histamine as a positive control agents in intradermal skin test.

Detailed Description

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Histamine hydrochloride and different concentrations of morphine sulfate will be intradermally injected and wheal diameter size will be comparatively measured between 15-30 minutes' time points after the test.

Conditions

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Intradermal Test

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* age 18-60 years old

Exclusion Criteria

* immunodeficiency state
* cancer
* severe skin diseases
* severe medical illnesses
* malnutrition
* uncontrolled asthma
* pregnancy
* received oral or systemic corticosteroid within 1 month before this study
* receiving immunosuppressive agents
* taken antihistamine within 3 days before this study
* taking beta-blocker
* previous history of immunotherapy
* have hypersensitivity reaction to morphine/opiates
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chulalongkorn University

OTHER

Sponsor Role lead

Responsible Party

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Chulalongkorn University

Principal Investigators

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Jettanong Klaewsongkram, MD

Role: PRINCIPAL_INVESTIGATOR

Chulalongkorn University

Locations

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Faculty of Medicine, Chulalongkorn University

Bangkok, , Thailand

Site Status

Countries

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Thailand

Other Identifiers

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Chula-ARC 001/09

Identifier Type: -

Identifier Source: org_study_id

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