Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
8 participants
INTERVENTIONAL
2008-02-29
2013-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Control group
The placebo group did not receive treatment during the matched period yet did undergo all assessments. The MS Placebo group received equal treatment following the study intervention period.
Usual Care - no active intervention
No treatment used for comparison
Combination Treadmill training group
Subjects randomized to Combination therapy received 20 minutes of Lokomat assisted treadmill training followed by up to 20 minutes of BWS treadmill training (without robotic assistance) twice a week.
Body-weight supported treadmill training +/- Lokomat assistance
walking
Interventions
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Body-weight supported treadmill training +/- Lokomat assistance
walking
Usual Care - no active intervention
No treatment used for comparison
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* EDSS level between 3.5-6.0
* Problems with ambulation
* able to ambulate 25 feet without an assistive device
Exclusion Criteria
* Unable to demonstrate an understanding of the process of the study and or fully understand instructions in order to safely participate in the study and use study equipment
* Body weight over 150 kg
25 Years
60 Years
ALL
No
Sponsors
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Mount Sinai Rehabilitation Hospital
OTHER
Responsible Party
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Jennifer Ruiz, DPT
Research Manager
Principal Investigators
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Albert Lo, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Mandell Center for Multiple Sclerosis at Mount Sinai Rehabilitation Hospital
Locations
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Mandell Center for Multiple Sclerosis at Mt. Sinai Rehabilitation Hospital
Hartford, Connecticut, United States
Countries
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References
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Fischer JS, LaRocca NG, Miller DM, Ritvo PG, Andrews H, Paty D. Recent developments in the assessment of quality of life in multiple sclerosis (MS). Mult Scler. 1999 Aug;5(4):251-9. doi: 10.1177/135245859900500410.
Vellas B, Baumgartner RN, Wayne SJ, Conceicao J, Lafont C, Albarede JL, Garry PJ. Relationship between malnutrition and falls in the elderly. Nutrition. 1992 Mar-Apr;8(2):105-8.
Duncan PW, Weiner DK, Chandler J, Studenski S. Functional reach: a new clinical measure of balance. J Gerontol. 1990 Nov;45(6):M192-7. doi: 10.1093/geronj/45.6.m192.
Liston RA, Brouwer BJ. Reliability and validity of measures obtained from stroke patients using the Balance Master. Arch Phys Med Rehabil. 1996 May;77(5):425-30. doi: 10.1016/s0003-9993(96)90028-3.
Related Links
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Mandell Center for Multiple Sclerosis home page
Other Identifiers
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AL0001
Identifier Type: -
Identifier Source: org_study_id
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