Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
11 participants
OBSERVATIONAL
2004-07-31
2006-03-31
Brief Summary
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People with sleep apnea and people who snore without sleep apnea may take part in this study. Sleep apnea is a disorder caused by pauses in breathing due to repetitive closure of the throat. The most common form of treatment for sleep apnea is continuous positive airway pressure (CPAP) therapy. While CPAP therapy remains the simplest and most effective treatment for snoring and sleep apnea, patients have to wear a nasal mask throughout the night. For this reason, patients often have difficulty sticking to therapy.
Participants enrolled in this study will spend 3-nights in a sleep laboratory. In all nights, the investigators will monitor your sleep and your breathing throughout the night. The investigators will apply several electrodes (sensors) to your scalp and face to monitor your sleep and breathing, and other sensors to your chest, abdomen, cheek, and a finger to monitor your breathing and oxygen level.
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Study Groups
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Sleep apnea
Patients with diagnosed obstructive sleep apnea
Trans Nasal Insufflation (TNI) [nasal canula]
Trans Nasal Insufflation, or TNI, uses air at flow rates delivered through a small nasal canula to reduce the severity and frequency of sleep apnea events.
By using TNI we hope to increase the amount of air that the patient can breathe during periods of obstructive sleep disordered breathing.
Interventions
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Trans Nasal Insufflation (TNI) [nasal canula]
Trans Nasal Insufflation, or TNI, uses air at flow rates delivered through a small nasal canula to reduce the severity and frequency of sleep apnea events.
By using TNI we hope to increase the amount of air that the patient can breathe during periods of obstructive sleep disordered breathing.
Eligibility Criteria
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Inclusion Criteria
* Diagnosed obstructive sleep apnea
Exclusion Criteria
* Uncontrolled hypertension (BP \> 190/110)
* Severe intrinsic lung diseases (supplemental O2 \> 2 L/min during the day)
* History of chronic renal insufficiency
* History of hepatic insufficiency
* Pregnancy
* Bleeding disorders or Coumadin use
* Sleep Disorders other than Obstructive Sleep Apnea (OSA)
* Tracheostomy
* Allergy to lidocaine
21 Years
ALL
No
Sponsors
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Johns Hopkins University
OTHER
Responsible Party
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Locations
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Johns Hopkins University
Baltimore, Maryland, United States
Countries
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References
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McGinley BM, Patil SP, Kirkness JP, Smith PL, Schwartz AR, Schneider H. A nasal cannula can be used to treat obstructive sleep apnea. Am J Respir Crit Care Med. 2007 Jul 15;176(2):194-200. doi: 10.1164/rccm.200609-1336OC. Epub 2007 Mar 15.
Other Identifiers
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NA_00019483
Identifier Type: -
Identifier Source: org_study_id
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