Primary and Secondary Hemostasis in Elective Coronary Artery Bypass Graft Surgery

NCT ID: NCT00825981

Last Updated: 2010-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-31

Study Completion Date

2010-03-31

Brief Summary

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Patients undergoing elective coronary artery bypass graft surgery (CABG) are treated with platelet inhibitors to reduce myocardial infarction and mortality.However, this can increase perioperative bleeding. A retrospective analysis of the data in our institution has revealed a significant increase in transfusion requirements after elective CABG since 5 years. The aim of our study is to observe if this increase in transfusion requirements is due to platelet inhibitors or due to other coagulation abnormalities resulting from other anticoagulants.

Detailed Description

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Conditions

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Coronary Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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coronary artery bypass graft

patients undergoing elective coronary artery bypass graft with or without cardiopulmonary bypass

screening coagulation abnormalities

Intervention Type OTHER

if specific coagulation abnormalities are observed which increase patient's risk of bleeding, appropriate treatment will start

Interventions

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screening coagulation abnormalities

if specific coagulation abnormalities are observed which increase patient's risk of bleeding, appropriate treatment will start

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* coronary artery bypass graft surgery with or without cardiopulmonary bypass

Exclusion Criteria

* emergency; redo cardiac surgery; combined cardiac surgery; patients with renal insufficiency; patients with acquired coagulation abnormalities
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cliniques universitaires Saint-Luc- Université Catholique de Louvain

OTHER

Sponsor Role lead

Responsible Party

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Cliniques Universitaires saint Luc

Locations

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Cliniques Universitaires Saint Luc

Brussels, Brussels Capital, Belgium

Site Status

Countries

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Belgium

References

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Hertfelder HJ, Bos M, Weber D, Winkler K, Hanfland P, Preusse CJ. Perioperative monitoring of primary and secondary hemostasis in coronary artery bypass grafting. Semin Thromb Hemost. 2005;31(4):426-40. doi: 10.1055/s-2005-916678.

Reference Type BACKGROUND
PMID: 16149021 (View on PubMed)

Other Identifiers

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2008/10DEC/350

Identifier Type: -

Identifier Source: org_study_id

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