Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
72 participants
INTERVENTIONAL
2005-04-30
2008-05-31
Brief Summary
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1. To examine the impact of recurrent partial sleep loss in young, middle-aged and older men and women. Sleep will be restricted to 4 hours.
2. To test the hypothesis that extending bedtimes to allow for sleep recovery will reverse the metabolic, endocrine, and cardiovascular and neuro-behavioral alterations resulting from sleep restriction. Sleep will be extended to 12 hours following the 4 hour sleep restriction.
3. To test the hypothesis that there are age and gender differences in the total amount of sleep recovery obtained during the week of 12-hour bedtimes.
4. To test the hypothesis that there are age and gender differences in sleep capacity (the amount of time an individual can sleep per night when there is no sleep debt).
5. To test the hypothesis that sleep capacity is partly determined by baseline levels of slow-wave sleep and slow-wave activity.
6. To determine whether sleep capacity is related to sleep need by examining metabolic, endocrine, cardiovascular and neuro-behavioral changes with the amount of the individual sleep debt.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
NONE
Study Groups
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Normal (8 hours) sleep time
Subjects are studied under normal sleep time conditions.
No interventions assigned to this group
Sleep restriction
Sleep restriction to 4 hours of sleep per night.
Overnight sleep recording, measures of endocrine and metabolic (from blood), cardiovascular (measures of blood pressure and heart rate), performance ( before and after sleep restriction and after sleep recovery.
Sleep restriction
Sleep restriction.
Interventions
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Sleep restriction
Sleep restriction.
Eligibility Criteria
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Inclusion Criteria
* healthy
* age 18-75 old
Exclusion Criteria
* irregular life habits (shift workers, travelers)
* smokers
* on medication
* consumption of \> 2 alcohol or caffeinated beverages/day
18 Years
75 Years
ALL
Yes
Sponsors
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University of Chicago
OTHER
Responsible Party
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Principal Investigators
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Eve Van Cauter, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Chicago
Locations
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The University of Chicago
Chicago, Illinois, United States
Countries
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Other Identifiers
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#13159A
Identifier Type: -
Identifier Source: org_study_id
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