Regulation of Hepatic Insulin Extraction

NCT ID: NCT00811044

Last Updated: 2018-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2000-10-31

Study Completion Date

2015-06-30

Brief Summary

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* This study is in the area of Type 2 diabetes and genetics
* Healthy Volunteers and those with mild type 2 diabetes may be eligible to participate
* This study is searching for genes that may affect the body's processing/digestion of glucose/sugar

Detailed Description

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This study is looking at the genetic influences of type 2 diabetes. It also is investigating the various gastric hormones including but not limited to: insulin, C-peptide, GIP, GLP, \& Xenin.

Conditions

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Diabetes

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Entry

This group is just entering the study and will need to be genotyped.

No interventions assigned to this group

Affected

This group has been genotyped and has the gene undergoing study at that time.

No interventions assigned to this group

Control

This group has been genotyped and does not have the gene currently under study.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* ages 18-65
* non-diabetic
* diabetes controlled with diet or with pills
* no family history of diabetes
* family history of type 2 diabetes
* personal history of gestational diabetes

Exclusion Criteria

* \< 18 or \> 65 years of age
* medications that affect glucose (sugar) levels
* kidney disease
* liver disease
* heart/cardiovascular disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Chicago

OTHER

Sponsor Role collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role collaborator

Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kenneth S Polonsky, MD

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Other Identifiers

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5R01DK031842-26

Identifier Type: NIH

Identifier Source: secondary_id

View Link

00-0589

Identifier Type: -

Identifier Source: org_study_id

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