Investigates Improvement in Vision Following Switching From Avastin and Macugen Over to Lucentis

NCT ID: NCT00804934

Last Updated: 2012-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-02-29

Study Completion Date

2009-01-31

Brief Summary

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The purpose of this study is to determine whether people who have received intermittent anti-VEGF therapy have an improvement in vision after being switched to monthly injections of Lucentis.

Detailed Description

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To determine mean change in visual acuity at 6 and 12 months

Conditions

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Wet AMD

Study Groups

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0

Lucentis

Intervention Type DRUG

0.5mg Lucentis every four months

Interventions

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Lucentis

0.5mg Lucentis every four months

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Ability to provide written informed consent and comply with study assessments for the full duration of the study
* Age greater then and equal 50 years
* Patients with active neovascular AMD
* Received at least 3 treatments with anti-VEGF therapy (bevacizumab or pegaptanib or ranibizumab) in the last 24 months
* If the patient has bilateral disease and qualifies for the study, both eyes may be included

Exclusion Criteria

* Subjects who meet any of the following criteria will be excluded from this study:
* Pregnancy or lactation
* Premenopausal women not using adequate contraception.
* Participation in another simultaneous medical investigation
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Retina Institute of Hawaii

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Debra L Shimabukuro, RN

Role: STUDY_CHAIR

Retina Institute of Hawaii

Locations

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Retina Institute of Hawaii

Honolulu, Hawaii, United States

Site Status

Countries

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United States

Other Identifiers

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F4421S

Identifier Type: -

Identifier Source: org_study_id

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