Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
18 participants
INTERVENTIONAL
2007-11-30
2007-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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A
Fluoride
Brush half mouth twice daily for four days
B
Triclosan
Brush half mouth daily for four days
Fluoride
Brush half mouth daily for four days
C
Chlorhexidine gluconate
Mouth rinsing with 15 ml for 30 seconds twice a day for four days
Interventions
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Fluoride
Brush half mouth twice daily for four days
Triclosan
Brush half mouth daily for four days
Chlorhexidine gluconate
Mouth rinsing with 15 ml for 30 seconds twice a day for four days
Fluoride
Brush half mouth daily for four days
Eligibility Criteria
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Inclusion Criteria
* Good general health
* Must sign informed consent form
* Minimum of 20 natural uncrowned teeth (excluding third molars) must be present.
* No history of allergy to personal care consumer products, or their ingredients, relevant to any ingredient in the test products as determined by the dental/medical professional monitoring the study.
Exclusion Criteria
2. Medical condition which requires pre-medication prior to dental visits/procedures
3. Moderate or advanced periodontal disease or heavy dental tartar (calculus).
4. 2 or more decayed untreated dental sites at screening.
5. Other disease of the hard or soft oral tissues.
6. Impaired salivary function (e.g. Sjogren's syndrome or head and neck irradiation).
7. Use of medications that can affect salivary flow (e.g. anticholinergics, adrenergics, antihistamines, vasoconstrictors or decongestants).
8. Use of antibiotics or antimicrobial drugs within 30 days prior to study visit #1.
9. Pregnant or nursing women.
10. Participation in any other clinical study within 1 week prior to enrollment into this study.
11. Allergy to chlorhexidine
12. Use of tobacco products
13. Subjects who must receive dental treatment during the study dates.
14. Current use of Antibiotics for any purpose.
15. Presence of an orthodontic appliance.
16. History of allergy to common dentifrice ingredients.
17. Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy)
18 Years
65 Years
ALL
Yes
Sponsors
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Colgate Palmolive
INDUSTRY
Responsible Party
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Colgate Palmolive
Principal Investigators
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Michael Deasy, DDS
Role: PRINCIPAL_INVESTIGATOR
Locations
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UMDNJ Dental School
Newark, New Jersey, United States
Countries
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Other Identifiers
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ATO-2007-PLA-01-RR
Identifier Type: -
Identifier Source: org_study_id