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Periodontal Disease and Cardiovascular Disease

NCT ID: NCT00763165

Last Updated: 2008-10-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

438 participants

Study Classification

INTERVENTIONAL

Study Start Date

2000-11-30

Study Completion Date

2009-12-31

Brief Summary

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To access the influence of triclosan dentifrice on the progression of periodontal disease in patients with coronary heart disease.

Detailed Description

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Conditions

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Periodontal Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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A

Group Type ACTIVE_COMPARATOR

Triclosan

Intervention Type DRUG

Brush twice daily

Fluoride

Intervention Type DRUG

Brush twice daily

B

Group Type PLACEBO_COMPARATOR

Fluoride

Intervention Type DRUG

Brush twice daily

Interventions

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Triclosan

Brush twice daily

Intervention Type DRUG

Fluoride

Brush twice daily

Intervention Type DRUG

Fluoride

Brush twice daily

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* A minimum of 12 uncrowned teeth other than 3rd molars
* Age 18 to 75 years
* Informed consent

Exclusion Criteria

* Prosthetic heart valves
* Prosthetic joint replacement
* Previous infective endocarditis
* Requirement for antibiotic cover for dental treatment
* Current treatment with warfarin
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Colgate Palmolive

INDUSTRY

Sponsor Role lead

Responsible Party

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Colgate Palmolive

Principal Investigators

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Gregory Seymour, BDS

Role: PRINCIPAL_INVESTIGATOR

Locations

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Discipline of Medicine

Chermside, , Australia

Site Status

Countries

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Australia

Other Identifiers

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D/06/Dent/99

Identifier Type: -

Identifier Source: org_study_id