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The Investigation of a Fluorescence/Elastic Scattering Spectroscopy (F-ESS) Device for Oral Tissue Characterization

NCT ID: NCT00764569

Last Updated: 2022-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

77 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-11-30

Study Completion Date

2011-06-30

Brief Summary

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The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.

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Detailed Description

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Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.

Conditions

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Other Lesions of Oral Mucosa

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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Oral Tissue measurement

Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement

Fluorescence/Elastic Scattering Spectroscopy

Intervention Type DEVICE

Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement

Interventions

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Fluorescence/Elastic Scattering Spectroscopy

Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* adult over 18 years of age

Exclusion Criteria

* younger than 18 years of age
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beckman Laser Institute University of California Irvine

OTHER

Sponsor Role collaborator

University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Beckman Laser Institute and Medical Center

Petra Wilder-Smith, DDS., PhD., Professor, Director of Dentistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Petra Wilder-Smith, DDS, PhD

Role: PRINCIPAL_INVESTIGATOR

Beckman Laser Institute University of California Irvine

Locations

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Beckman Laser Institute Medical clinic

Irvine, California, United States

Site Status

UCI student health center

Irvine, California, United States

Site Status

Countries

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United States

Other Identifiers

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20086355

Identifier Type: -

Identifier Source: org_study_id

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