Memantine as Adjunctive Therapy for Schizophrenia Negative Symptoms
NCT ID: NCT00757978
Last Updated: 2008-12-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
22 participants
INTERVENTIONAL
2006-01-31
2008-03-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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1
Clozapine plus placebo
placebo
1 capsule of placebo twice a day
2
Clozapine plus memantine
memantine
memantine 10mg twice a day
Interventions
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memantine
memantine 10mg twice a day
placebo
1 capsule of placebo twice a day
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Lactation
18 Years
60 Years
ALL
No
Sponsors
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Hospital de Clinicas de Porto Alegre
OTHER
Responsible Party
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Hospital de Clinicas de Porto Alegre
Principal Investigators
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Clarissa S Gama, PhD
Role: STUDY_DIRECTOR
Hospital de Clinicas de Porto Alegre
Locations
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Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil
Countries
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References
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de Lucena D, Fernandes BS, Berk M, Dodd S, Medeiros DW, Pedrini M, Kunz M, Gomes FA, Giglio LF, Lobato MI, Belmonte-de-Abreu PS, Gama CS. Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. J Clin Psychiatry. 2009 Oct;70(10):1416-23. doi: 10.4088/JCP.08m04935gry.
Other Identifiers
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FIPE-HCPA 05-406
Identifier Type: -
Identifier Source: secondary_id
05-406
Identifier Type: -
Identifier Source: org_study_id