Effectiveness and Tolerability of an Oral Nutritional Supplement (PreOP Booster) Given Before Surgery

NCT ID: NCT00730808

Last Updated: 2010-05-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-12-31

Study Completion Date

2009-11-30

Brief Summary

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The aim of this pilot study is to investigate effectiveness, tolerability and safety of an oral nutritional supplement (PreOP Booster), given to rectal tumour patients prior to low anterior resection.

Detailed Description

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Conditions

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Rectal Tumors

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Test

Oral nutritional supplement: assignment according to consecutive random numbers.

Group Type EXPERIMENTAL

PreOP Booster (food for special medical purposes)

Intervention Type DIETARY_SUPPLEMENT

3x1 dosage is given prior to surgery: 2x1 the day prior to surgery; 1x1 3-4h prior to initiation of anaesthesia;

Control

Assignment according to consecutive random numbers.

Group Type PLACEBO_COMPARATOR

PreOP Booster (food for special medical purposes)

Intervention Type DIETARY_SUPPLEMENT

3x1 dosage is given prior to surgery: 2x1 the day prior to surgery; 1x1 3-4h prior to initiation of anaesthesia;

Interventions

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PreOP Booster (food for special medical purposes)

3x1 dosage is given prior to surgery: 2x1 the day prior to surgery; 1x1 3-4h prior to initiation of anaesthesia;

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* rectal tumour with indication for elective low anterior resection (open surgery, not laparoscopic surgery) or abdominoperineal resection (APR)
* preoperative radiotherapy (5x5 Gy) or chemoradiation
* loop ileostoma or colostoma;

Exclusion Criteria

* severe malnutrition
* severe renal insufficiency
* diabetes mellitus I or II
* concomitant thyroid medication
* corticosteroids
* diuretic medication and antihypertensive medication
* known or suspected allergy to any component of the investigational product(s)
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fresenius Kabi

INDUSTRY

Sponsor Role lead

Responsible Party

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Kabi Innovation Centre, Fresenius Kabi Deutschland GmbH

Principal Investigators

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Paul A.M. van Leeuwen, Prof.

Role: STUDY_CHAIR

University Hospital Amsterdam; The Netherlands

Locations

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Medical Center Alkmaar

Alkmaar, , Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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N-POB-04-NL

Identifier Type: -

Identifier Source: org_study_id

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