Usefulness of Balanced High Protein Supplementation on Recovery and Clinical Outcomes After Chemotherapy

NCT ID: NCT05938504

Last Updated: 2023-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

154 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-14

Study Completion Date

2025-02-28

Brief Summary

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The goal of this clinical trial is to find usefulness of balanced high protein supplementation on muscle function recovery and clinical outcomes after chemotherapy.

Participants will intake test or placebo oral nutritional supplements. Researchers will compare test groups and placebo groups to see if test oral supplements are more useful in muscle function recovery and clinical outcomes.

Detailed Description

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Conditions

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Colorectal Neoplasms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Control group

Subjects will receive two packs of placebo ONS (ONS\_320275) orally daily

Group Type PLACEBO_COMPARATOR

ONS_320275

Intervention Type OTHER

Subjects will consume two packs (165ml/pack) of placebo ONS (ONS\_320275) orally daily at any time of day.

Test group

Subjects will receive two packs of test ONS (ONS\_211567) orally daily

Group Type EXPERIMENTAL

ONS_211567

Intervention Type OTHER

Subjects will consume two packs (165ml/pack) of test ONS (ONS\_211567) orally daily at any time of day.

Interventions

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ONS_320275

Subjects will consume two packs (165ml/pack) of placebo ONS (ONS\_320275) orally daily at any time of day.

Intervention Type OTHER

ONS_211567

Subjects will consume two packs (165ml/pack) of test ONS (ONS\_211567) orally daily at any time of day.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* A person aged 19 or older
* A person who is diagnosed with direct colorectal cancer and begins chemotherapy
* A person who voluntarily agreed to participate in this trial and signed a informed consent form

Exclusion Criteria

* A person who has previously been diagnosed with cancer
* A person with a BMI of 30.0 kg/m2 or more
* A person who is diabetes mellitus with whose blood sugar is not controlled even when taking medication

* More than 126mg/dL of fasting blood sugar even on diabetes medication
* A person diagnosed with hypertension whose blood pressure is not controlled even when taking medication

* Systolic blood pressure 160mmHg or diastolic blood pressure 100mmHg or higher even when taking hypertension medication
* A person with renal dysfunction (up 1.5 times the upper limit of Creatinine normal) and liver dysfunction (up 2.5 times the upper limit of AST and ALT normal)
* A person with a serious musculoskeletal problem
* A person who has been diagnosed with acute or serious diseases (e.g., liver, kidney, heart, thyroid disease, etc.) or is on medication
* A person who has continuously taken health functional foods related to the ability to perform exercise within three months before visiting (Hormones, muscle enhancers, protein supplementation and muscle function improvement)
* A person who is allergic or overreacting to the ingredients of a test product

* All ingredients of the test product shall be specified in the consent form, and all ingredients that may cause allergies, such as sodium casein, shall be checked during screening
* A person who has participated in another clinical trial or a drug clinical trial within one month of the commencement of this test
* A person who is illiterate or whose ability is limited
* A person who is pregnant or lactating
* A person judged inappropriate by a researcher to participate in this study for other reasons
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nutriworks

INDUSTRY

Sponsor Role collaborator

Daesang Wellife

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Seoul St. Mary's hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Joo Hyun Park

Role: CONTACT

(+82) 80-996-6262

Facility Contacts

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Seunggyu Yoon

Role: primary

(+82) 02-2258-1511

Other Identifiers

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PROFIT

Identifier Type: -

Identifier Source: org_study_id

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