Comparison of Coronary CT Angiography With Conventional Coronary Angiography in Liver and Lung Transplant Candidates
NCT ID: NCT00727051
Last Updated: 2019-07-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
OBSERVATIONAL
2007-06-30
2014-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Study Groups
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1
Liver and lung transplant candidates referred for coronary angiography will be invited to participate in the study.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Patients with suspicious symptoms for CAD or;
* Asymptomatic patients;
* Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF \< 60% on echo.
2. Lung transplant candidates referred for invasive coronary angiography which include:
* Patients with suspicious symptoms for CAD or;
* Asymptomatic patients;
* Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF \< 60% on echo in patients with low SVR (typical for ESLD).
3. Any ethnic background is acceptable.
Exclusion Criteria
2. Children and pregnant women will be excluded because of risks associated with radiation exposure.
3. Patients must have no atrial fibrillation, as this will interfere with cardiac gating for the examination.
4. Patients unable to give informed consent will be excluded as well.
18 Years
ALL
No
Sponsors
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University of California, San Francisco
OTHER
Responsible Party
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Principal Investigators
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Karen G Ordovas, MD
Role: PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Locations
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UCSF Medical Center
San Francisco, California, United States
Countries
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References
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Zoghbi GJ, Patel AD, Ershadi RE, Heo J, Bynon JS, Iskandrian AE. Usefulness of preoperative stress perfusion imaging in predicting prognosis after liver transplantation. Am J Cardiol. 2003 Nov 1;92(9):1066-71. doi: 10.1016/j.amjcard.2003.06.003.
Findlay JY, Keegan MT, Pellikka PP, Rosen CB, Plevak DJ. Preoperative dobutamine stress echocardiography, intraoperative events, and intraoperative myocardial injury in liver transplantation. Transplant Proc. 2005 Jun;37(5):2209-13. doi: 10.1016/j.transproceed.2005.03.023.
Davidson CJ, Gheorghiade M, Flaherty JD, Elliot MD, Reddy SP, Wang NC, Sundaram SA, Flamm SL, Blei AT, Abecassis MI, Bonow RO. Predictive value of stress myocardial perfusion imaging in liver transplant candidates. Am J Cardiol. 2002 Feb 1;89(3):359-60. doi: 10.1016/s0002-9149(01)02244-5. No abstract available.
Snell GI, Richardson M, Griffiths AP, Williams TJ, Esmore DS. Coronary artery disease in potential lung transplant recipients > 50 years old: the role of coronary intervention. Chest. 1999 Oct;116(4):874-9. doi: 10.1378/chest.116.4.874.
Kaza AK, Dietz JF, Kern JA, Jones DR, Robbins MK, Fiser SM, Long SM, Bergin JD, Kron IL, Tribble CG. Coronary risk stratification in patients with end-stage lung disease. J Heart Lung Transplant. 2002 Mar;21(3):334-9. doi: 10.1016/s1053-2498(01)00387-4.
Ben-Dor I, Shitrit D, Kramer MR, Iakobishvili Z, Sahar G, Hasdai D. Is routine coronary angiography and revascularization indicated among patients undergoing evaluation for lung transplantation? Chest. 2005 Oct;128(4):2557-62. doi: 10.1378/chest.128.4.2557.
Herzog C, Britten M, Balzer JO, Mack MG, Zangos S, Ackermann H, Schaechinger V, Schaller S, Flohr T, Vogl TJ. Multidetector-row cardiac CT: diagnostic value of calcium scoring and CT coronary angiography in patients with symptomatic, but atypical, chest pain. Eur Radiol. 2004 Feb;14(2):169-77. doi: 10.1007/s00330-003-2197-9. Epub 2003 Dec 20.
Leschka S, Alkadhi H, Plass A, Desbiolles L, Grunenfelder J, Marincek B, Wildermuth S. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J. 2005 Aug;26(15):1482-7. doi: 10.1093/eurheartj/ehi261. Epub 2005 Apr 19.
Raff GL, Gallagher MJ, O'Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005 Aug 2;46(3):552-7. doi: 10.1016/j.jacc.2005.05.056.
Pannu HK, Alvarez W Jr, Fishman EK. Beta-blockers for cardiac CT: a primer for the radiologist. AJR Am J Roentgenol. 2006 Jun;186(6 Suppl 2):S341-5. doi: 10.2214/AJR.04.1944.
Other Identifiers
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H9730-30837
Identifier Type: -
Identifier Source: org_study_id
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