Determining Quality of Life in Breast Cancer Patient After Completing Radiation,Chemotherapy,Surgery or Combination

NCT ID: NCT00712621

Last Updated: 2009-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE2

Total Enrollment

460 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-02-28

Study Completion Date

2014-02-28

Brief Summary

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Rationale: Determining quality of life in breast cancer patient after completing chemotherapy or radiation therapy or surgical procedures or any combination therapy.

Intervention includes supportive care in terms of psychological support and moral boosting efforts by counseling breast cancer survivors which may enhance the well-being and quality of life of women who are treated with chemotherapy or radiation therapy or surgical procedures or any given combination therapy.

PURPOSE: Randomized clinical trial study to compare the effectiveness of support system and counseling of breast cancer survivors on the well-being of women, who have completed various modes of treatment of breast cancer with the subjects who have no support system.

Study Type: Quality of life and survival

Study Design: Two arm randomized controlled clinical trial to study quality of life and survival of breast cancer patients after completion of chemotherapy or radiation therapy or surgery or any combination therapy. The stages from I to IV (metastases to other sites of the body) are included.

Detailed Description

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OBJECTIVES:

* Determine the quality of life in breast cancer patient after completing chemotherapy or radiation therapy or surgical procedures or any combination therapy in both Arms.
* Determine the effect of providing standard written materials in Arm I.
* Determine the effect of psychological support and moral boosting efforts by counseling breast cancer survivors which may enhance the well-being and quality of life of women who are treated with chemotherapy or radiation therapy or surgical procedures or any combination therapy in Arm II.
* Determine the effect of socioeconomic status on all available demographic area which is not a criteria for exclusion in both Arms.
* Determine psychosocial and mental state to measure wellness and good quality of life in both Arms.
* Determine the periodic medical care for related or unrelated problems of the disease which have a positive impact on the survival and quality of life in both Arms.

Conditions

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Breast Carcinoma

Keywords

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Genetics Home Reference related topics breast cancer breast cancer related to depression Condition Stage I-IV Carcinoma of Breast

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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I

OUTLINE: This is a randomized, multicenter study. Patients are selected according to age ( 25 to 49 vs 50 to 85), time since initial completion of therapy (3 to 18 months), and are separated in two groups.

Arm I: Quality of life is assessed at baseline and at 3 and 6 months.

Group Type OTHER

Written materials

Intervention Type BEHAVIORAL

• Arm I: Patients receive the support by providing existing resources. Patients receive standard written materials from the counseling group after enrolling in the study.

II

OUTLINE: This is a randomized, multicenter study. Patients are selected according to age ( 25 to 49 vs 50 to 85), time since initial completion of therapy (3 to 18 months), and are separated in two groups.

Arm II: Quality of life is assessed at baseline and at 3 and 6 months.

Group Type OTHER

Counseling

Intervention Type BEHAVIORAL

• Arm II: Patients receive audio visual aids and weekly counseling sessions by the expert counselors and breast cancer survivors over 8 weeks for a total of 8-16 sessions. Patients receive written materials from the counseling group after the completion of the sessions

Interventions

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Counseling

• Arm II: Patients receive audio visual aids and weekly counseling sessions by the expert counselors and breast cancer survivors over 8 weeks for a total of 8-16 sessions. Patients receive written materials from the counseling group after the completion of the sessions

Intervention Type BEHAVIORAL

Written materials

• Arm I: Patients receive the support by providing existing resources. Patients receive standard written materials from the counseling group after enrolling in the study.

Intervention Type BEHAVIORAL

Other Intervention Names

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Lifestyle Counseling Quality of Life

Eligibility Criteria

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Inclusion Criteria

* Breast cancer patients
* 25 to 85 years old

DISEASE CHARACTERISTICS:

* Received prior definitive treatment for stage I-IV breast cancer with or without adjuvant chemotherapy or radiation therapy or surgical therapy or any combination therapy.
* 3 to 18 months since completion therapy.

PATIENT CHARACTERISTICS:

Age:

* 25 to 49 vs 50 to 85

Sex:

* Female

Menopausal status:

* Not specified

Performance status:

* Not specified

Life expectancy:

* Not specified

Hematopoietic:

* CBC in normal range:
* Hemoglobin - 10 g/dl
* Blood Glucose is twofold above the normal range

Hepatic:

* Hepatic profile is twofold above the normal range:
* AST/ALT
* Bilirubin,total
* Protein (Albumin, Globulin)

Renal:

* Renal tests are twofold above the normal range:
* Creatinine clearance 24 hours
* BUN
* Creatinine level

Other:

* No current psychiatric diagnosis
* Mini Mental Status Examination
* No signs and symptoms MDD
* Anxiety disorder
* Post Traumatic Syndrome Disorder

Status of Therapy:

Chemotherapy:

* Completed

Endocrine therapy:

* Completed

Radiotherapy:

* Completed

Surgery:

* Completed at least three months before the start of the study

Exclusion Criteria

* Age below 25 and above 85
* Subject with breast carcinoma in therapy
* Any current mental illness
* Hepatic enzymes are more than twofold from the normal range
* Renal impairment is more than twofold from the normal range
* Hemoglobin is less than 10 g/dl
* CBC results are below normal range
Minimum Eligible Age

25 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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American Scitech International

OTHER

Sponsor Role lead

Responsible Party

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American Scitech International

Principal Investigators

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Prem A Nandiwada, MD

Role: PRINCIPAL_INVESTIGATOR

Raritan Bay Medical Center

Ratna Grewal, MD

Role: STUDY_CHAIR

American Scitech International-eCRO

Sarat Babu, MD

Role: STUDY_DIRECTOR

St. Peter's Hospital

Locations

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Practicing physician in New Jersey

Englishtown, New Jersey, United States

Site Status

Countries

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United States

Other Identifiers

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ASI-QOL8655

Identifier Type: -

Identifier Source: secondary_id

ASI-QOLII0608

Identifier Type: -

Identifier Source: org_study_id