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Limitations of Using a Sheimpflug Image-Based Device for Measuring Anterior Chamber Depth in Pseudophakic Eyes

NCT ID: NCT00712231

Last Updated: 2008-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

184 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2008-02-29

Brief Summary

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There have been numerous studies comparing various ACD measurements in phakic eyes,while researches comparing ACD in pseudophakic eyes are less extensive. With the recent popularity of presbyopia correction, measuring the ACD will facilitate differentiating pseudophakic accommodation from pseudoaccommodation. It is thus mandatory to verify the accuracy of ACD measurement of these devices since the innovation of various IOLs in the recent decade makes this task more complicated. In this study, we will assess the limitations of using Pentacam for ACD measurement in pseudophakic eyes and compare Pentacam measurement with IOLMaster and A-scan measurements.

Detailed Description

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In this prospective study, ACD was measured in 90 phakic and 94 pseudophakic eyes by Pentacam, IOLMaster and A-scan. Correlations and differences between the three measurements were investigated. The accuracy in detecting the anterior lens surface in pseudophakic eyes was also assessed.Differences in ACD-Pen, ACD-IOLM, and ACD-A were analyzed using one-way analysis of variance (ANOVA). When an overall significance of P\< 0.05 was obtained, pair-wise comparisons were made using Tukey's multiple comparison t tests. The association between ACD-Pen, ACD-IOLM, and ACD-A was assessed using Pearson's correlation test. The distribution of erroneous ACD-Pen measurement for the three IOLs was analyzed with the chi-square test. In all analyses, P \<0.05 was considered statistically significant.

Conditions

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Cataract

Keywords

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pseudophakic anterior chamber depth Pentacam

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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phakic eyes

the cases did not accept any intraocular surgery

No interventions assigned to this group

pseudophakic eyes

tht cases did not accept any intraocular surgery expect for cataract surgery

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Phakic group: randomized
* Pseudophakic eyes : the cases accepted cataract surgery

Exclusion Criteria

* Previous ocular trauma or intraocular surgery other than cataract surgery;
* Contact lens use in the past two months;
* Use of medication that might affect the pupil; corneal disease or ocular infection;
* History of ocular disease, such as

* Dry eye syndrome
* Uveitis
* Glaucoma
* Ocular tumor
* Cases with any surgical complications were also excluded.
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Far Eastern Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Far Eastern Memorial Hospital

Principal Investigators

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Shu-Wen Chang

Role: PRINCIPAL_INVESTIGATOR

Far Eastern Memorial Hospital

Other Identifiers

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FEMH97007

Identifier Type: -

Identifier Source: org_study_id