Researching AXIUM Coiling Experience and Recanalization (RACER)

NCT ID: NCT00703794

Last Updated: 2018-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

119 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-06-30

Study Completion Date

2012-01-16

Brief Summary

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The data collected in this study will be used to support International Regulatory submissions. The study objective is to evaluate the continued safety and efficacy of the AXIUM Progressive Coil System.

This Device has been used clinically at approximately 150 Institutions under FDA 510(k) clearance since April 24, 2007. The device received CE authorization on June 30, 2007. Through December 2007, more than 1000 patients have been treated with the AXIUM Coils.

Detailed Description

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Conditions

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Aneurysms Vascular Diseases Cerebrovascular Disorders Intracranial Arterial Diseases

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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AXIUM Coils

The AXIUM Progressive Coil System

Intervention Type DEVICE

Embolization of aneurysm

Interventions

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The AXIUM Progressive Coil System

Embolization of aneurysm

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient or patient's legally authorized representative has signed and dated an Informed Consent Form
* Must be at least 18 years of age
* Aneurysm location, angio-architecture, morphology, or medical condition, is considered by the neurosurgical / interventional team to be at very high risk for management by traditional operative techniques, or aneurysm is considered to be inoperable
* Patient is willing to conduct follow-up visits

Exclusion Criteria

* Aneurysm was previously treated
* Patient has a cerebral aneurysm with a location, angioarchitecture or morphology that presents an unacceptable risk of morbidity due to the Study procedures
* Patient is participating in another clinical research Study
* Patient has a medical, social or psychological condition, which precludes the patient from receiving Study required treatment, evaluation, procedures and follow-up
* Female patient is pregnant or breast-feeding
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Neurovascular Clinical Affairs

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ajay K Wakhloo, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Massachusetts, Worcester

Locations

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Kaleida Health - Millard Fillmore

Buffalo, New York, United States

Site Status

Cleveland Clinic Foundation

Cleveland, Ohio, United States

Site Status

Lac+Usc/Uscuh

Los Angeles, California, United States

Site Status

Vascular and Interventional Specialists of Orange County, Inc. - St. Joseph Hospital of Orange

Orange, California, United States

Site Status

Lee Memorial Health System

Fort Myers, Florida, United States

Site Status

University of Miami - Jackson Memorial Hospital Systems

Miami, Florida, United States

Site Status

Bayfront Medical Center

St. Petersburg, Florida, United States

Site Status

Tampa General Hospital

Tampa, Florida, United States

Site Status

Neurologic & Orthopedic Hospital of Chicago (NOHC)

Chicago, Illinois, United States

Site Status

Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status

University of Massachusetts Medical Center

Worcester, Massachusetts, United States

Site Status

Abbott Northwestern

Minneapolis, Minnesota, United States

Site Status

Oregon Health & Science University (OHSU)

Portland, Oregon, United States

Site Status

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Site Status

Medical University of South Carolina (MUSC)

Charleston, South Carolina, United States

Site Status

Palmetto Richland Health Memorial Hospital

Columbia, South Carolina, United States

Site Status

Fletcher Allen Health Care

Burlington, Vermont, United States

Site Status

University of Wisconsin

Madison, Wisconsin, United States

Site Status

Countries

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United States

References

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Casasco AE, Aymard A, Gobin YP, Houdart E, Rogopoulos A, George B, Hodes JE, Cophignon J, Merland JJ. Selective endovascular treatment of 71 intracranial aneurysms with platinum coils. J Neurosurg. 1993 Jul;79(1):3-10. doi: 10.3171/jns.1993.79.1.0003.

Reference Type BACKGROUND
PMID: 8315465 (View on PubMed)

Wakhloo AK, Gounis MJ, Sandhu JS, Akkawi N, Schenck AE, Linfante I. Complex-shaped platinum coils for brain aneurysms: higher packing density, improved biomechanical stability, and midterm angiographic outcome. AJNR Am J Neuroradiol. 2007 Aug;28(7):1395-400. doi: 10.3174/ajnr.A0542.

Reference Type BACKGROUND
PMID: 17698550 (View on PubMed)

Linfante I, Wakhloo AK. Brain aneurysms and arteriovenous malformations: advancements and emerging treatments in endovascular embolization. Stroke. 2007 Apr;38(4):1411-7. doi: 10.1161/01.STR.0000259824.10732.bb. Epub 2007 Feb 22.

Reference Type BACKGROUND
PMID: 17322071 (View on PubMed)

Razack N, Thompson BG. Treatment of intracranial aneurysms: clipping or coiling? J Neuroophthalmol. 2004 Mar;24(1):1-2. doi: 10.1097/00041327-200403000-00001. No abstract available.

Reference Type BACKGROUND
PMID: 15206430 (View on PubMed)

Mericle RA, Reig AS, Burry MV, Eskioglu E, Firment CS, Santra S. Endovascular surgery for proximal posterior inferior cerebellar artery aneurysms: an analysis of Glasgow Outcome Score by Hunt-Hess grades. Neurosurgery. 2006 Apr;58(4):619-25; discussion 619-25. doi: 10.1227/01.NEU.0000204127.81249.28.

Reference Type BACKGROUND
PMID: 16575325 (View on PubMed)

Thornton J, Debrun GM, Aletich VA, Bashir Q, Charbel FT, Ausman J. Follow-up angiography of intracranial aneurysms treated with endovascular placement of Guglielmi detachable coils. Neurosurgery. 2002 Feb;50(2):239-49; discussion 249-50. doi: 10.1097/00006123-200202000-00003.

Reference Type BACKGROUND
PMID: 11844258 (View on PubMed)

Related Links

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Other Identifiers

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ev3-FD1942-CR00045

Identifier Type: -

Identifier Source: org_study_id

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