The Effect of Balance Training on Unloading Reaction in Individuals With Functional Ankle Instability
NCT ID: NCT00703456
Last Updated: 2016-04-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2008-06-30
2009-05-31
Brief Summary
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We hypothesize that experimental FAI group will demonstrate a significant decline in unloading reaction following balance training while FAI control group will not show a significant decline in unloading reaction without training. We further hypothesize that experimental FAI group will demonstrate a significant improvement in the FAI score after the balance training measured by Ankle Instability questionnaire. Following balance training, there will be a significant correlation between the change in FAI score and change in the unloading reaction in the experimental group.
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Detailed Description
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Hyper-reactivity of the ankle joint with FAI may be an important factor for the ankle "giving way" episode. Patients may develop injury-induced hyper-reactivity for unloading reaction through an adaptation to physical conditions of the ankle joint after injury. Clinical studies performed with selective nerve blocks along with electrophysiology studies performed in animals have led to the generally accepted conclusion that enhanced pain induced by peripheral nerve injury is associated with increased spontaneous and evoked discharges from injured and/or adjacent uninjured nerves. Persistent primary afferent inputs are believed to cause a state of central (i.e. "spinal") sensitization and enhancing responses to sensory inputs i.e. hyper-reactivity.
The ankle "giving way" is a complex phenomenon where any mechanical and neuromuscular factor or a combination of mechanical and neuromuscular factors may be at fault including ankle hyper-reactivity, joint laxity, proprioceptive deficit, and muscle weakness. The purpose of this study is to examine the effect of balance training intervention on the various etiological factors of FAI and to develop an objective measurement for physiological features related to FAI.
The study will help us to understand the mechanism of balance training on FAI and help us to determine the scope and limitations of balance training on FAI subjects in clinical settings to evaluate treatment efficacy.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SINGLE
Study Groups
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1
Balance Training, 3 times a week for 4 weeks
Balance Training
balance training three days per week for 4 weeks during single limb standing
2
Education/No intervention
No interventions assigned to this group
Interventions
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Balance Training
balance training three days per week for 4 weeks during single limb standing
Eligibility Criteria
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Inclusion Criteria
* unilateral functional ankle instability (grade II or III)
* at least four weeks after acute lateral ankle sprain
* ongoing symptom of ankle "giving way" episode during functional activities
* active in exercise at least 2 hour per week
* seeking medical treatment for ankle symptoms
* being able to complete the test and training tasks.
Exclusion Criteria
* ankle surgery in either leg
* gross limitation in ankle range of motion
* lower extremity injury other than lateral ankle sprain in past 12 weeks, (5) current enrollment in formal rehabilitation program
* history of insulin-dependent diabetes
* any systemic disease that might interfere with sensory input or muscle function of the lower extremity
* any joint disease or bony fracture in the lower extremity
* any previous experience of intolerance to electrical stimulation.
18 Years
45 Years
ALL
No
Sponsors
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University of Kansas Medical Center
OTHER
Responsible Party
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Principal Investigators
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Wen Liu
Role: PRINCIPAL_INVESTIGATOR
University of Kansas Medical Center
Locations
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University of Kansas Medical Center
Kansas City, Kansas, United States
Countries
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Other Identifiers
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10866
Identifier Type: -
Identifier Source: org_study_id
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