Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
120 participants
INTERVENTIONAL
2002-05-31
2003-06-30
Brief Summary
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We conducted a 12-month population-based randomized controlled exercise intervention in 120 premenopausal women. The aim was to investigate the effect of impact exercise on bone mineral density, geometry and metabolism in healthy women with the intention of assessing the intensity and amount of impact loading with a novel accelerometer-based measurement device. Training effects on risk factors of osteoporotic fractures, physical performance and risk factors of cardiovascular diseases were also evaluated.
This study demonstrated that 12 months of regular impact exercise favoured bone formation, increased bone mineral density in weight-bearing bones, especially at the hip, and led to geometric adaptations by increasing periosteal circumference. Bone adaptations had a dose- and intensity-dependent relationship with measured impact loading. Changes in proximal femur were threshold-dependent, indicating the importance of high impacts exceeding acceleration of 4 g as an osteogenic stimulus. The number of impacts needed to achieve this stimulation was 60 per day. Impact exercise also had a favourable effect on physical performance and cardiorespiratory risk factors by increasing maximal oxygen uptake, dynamic leg strength and decreasing low-density lipoproteins and waist circumference. Changes were dose-dependent with impact loading at wide intensity range.
Bone adapts to impact loading through various mechanisms to ensure optimal bone strength. The number of impacts needed to achieve bone stimulation appeared to be 60 per day, comparable to the same number of daily jumps. If done on a regular basis, impact exercise may be an efficient and safe way of preventing osteoporosis.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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2
Control group
No interventions assigned to this group
1
Exercise
Exercise
Progressive impact exercise
Interventions
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Exercise
Progressive impact exercise
Eligibility Criteria
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Inclusion Criteria
* Age 35-40 yr
* residing in the city of Oulu, Finland
* in March 2002
Exclusion Criteria
* diseases or medication affecting the bone
* pregnancy and breastfeeding
* regular current or previous participation in impact-type exercises and long-distance running more than three times a week
35 Years
40 Years
FEMALE
No
Sponsors
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Oulu Deaconess Institute
OTHER
UKK Institute
OTHER
Finnish Institute of Occupational Health
OTHER
The Finnish Funding Agency for Technology and Innovation (TEKES)
OTHER_GOV
Newtest Ltd
UNKNOWN
CCC Group Ltd.
INDUSTRY
Fastrax Ltd.
INDUSTRY
University of Oulu
OTHER
Responsible Party
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University of Oulu
Locations
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University of Oulu
Oulu, , Finland
Countries
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References
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Ahola R, Korpelainen R, Vainionpaa A, Leppaluoto J, Jamsa T. Time-course of exercise and its association with 12-month bone changes. BMC Musculoskelet Disord. 2009 Nov 12;10:138. doi: 10.1186/1471-2474-10-138.
Other Identifiers
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40093/02
Identifier Type: -
Identifier Source: org_study_id