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The Effect of 16 Weeks of Hip Adduction and Abduction Resistance Exercise

NCT ID: NCT01228877

Last Updated: 2017-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-12-31

Study Completion Date

2012-09-30

Brief Summary

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Performing adduction and abduction resistance exercise will increase hip bone density and strength to a greater extent than doing squat and deadlift exercise.

Aim #1: To determine if doing hip adduction and abduction resistance exercise training for 16 weeks improves spine bone mineral density and hip bone mineral density and strength as determined by finite element modeling.

Aim #2: To compare the effects of hip adduction and abduction exercise to squat and deadlift exercise with respect to potential changes in hip bone mineral density and strength.

Aim #3: To determine if the addition of adduction and abduction exercise to squat and deadlift exercise promotes an "additive" effect with respect to changes in spine bone mineral density and hip bone mineral density and bone strength.

Detailed Description

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The investigators will carry out a 16-week exercise training study (n=24) consisting of 3 groups (n=8 per group) of healthy, non-resistance trained adult men and women (age 25-55 years). Our aim is to determine if hip adduction and abduction resistance exercise is more effective than squat and deadlift exercise with respect to changes in the whole bone strength and density of the proximal femur and spine.

Group A will do only hip adduction and abduction exercises. Group B will do only squat and deadlift exercise Group C will do a combination of hip adduction and abduction and squat and deadlift exercise

Subjects will be imaged with quantitative computed tomography (QCT) of the proximal femur and spine, pre-training and post-training, to determine changes in spinal bone density and proximal femoral bone density and strength.

Serum assays of bone formation (osteocalcin) and bone resorption (serum CTX type I) will be performed four times during the study at 4 week intervals.

Conditions

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Osteoporosis Osteopenia Sarcopenia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Exercise

Adduction, Abduction and Squat exercise three times a week for 16 weeks

Group Type EXPERIMENTAL

exercise

Intervention Type OTHER

Adduction, Abduction and Squat exercise three times a week for 16 weeks

Interventions

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exercise

Adduction, Abduction and Squat exercise three times a week for 16 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy men and women
* Age of 25 to 55 years old

Exclusion Criteria

* Hypertension (High blood pressure)
* Diabetes or metabolic syndrome
* Hyperlipidemia (High cholesterol)
* Cardiovascular Disease
* Asthma or other pulmonary disease (i.e. COPD)
* not pregnant
* have no joint or mobility limitations
* do not exercise on a regular basis
Minimum Eligible Age

25 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Space Biomedical Research Institute

OTHER

Sponsor Role collaborator

University of California, San Francisco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thomas Lang, PhD

Role: PRINCIPAL_INVESTIGATOR

UCSF-Department of Radiology

Locations

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UCSF-Department of radiology-China Basin

San Francisco, California, United States

Site Status

Countries

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United States

Other Identifiers

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Ad/Ab exercise

Identifier Type: -

Identifier Source: org_study_id