Angiogenesis With Positron Emission Tomography (PET) Tracer Uptake
NCT ID: NCT00671242
Last Updated: 2008-05-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
OBSERVATIONAL
Brief Summary
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Method: Thirty-seven NSCLC patients were enrolled in this study, and a pair of PET study with 18F-FMT and 18F-FDG was performed. Uptake of PET tracers was evaluated with standardized uptake value. VEGF, CD31, CD34, LAT1 and Ki-67 labeling index of the resected tumors were analyzed by immunohistochemical staining, and correlated with the clinicopathologic variables and the uptake of PET tracers.
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Detailed Description
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Conditions
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Study Groups
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I
L-\[3-18F\]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for PET. We have conducted a clinicopathologic study to elucidate the correlation of angiogenesis with 18F-FMT and 18F-FDG uptake in the patients with non-small cell lung cancer
No interventions assigned to this group
Nuclear
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Histology is non-small cell lung cancer
Exclusion Criteria
* Patients who have insulin-dependent diabetes
ALL
No
Sponsors
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J~pharma
INDUSTRY
Gunma University
OTHER
Locations
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Gunma University Graduate School of Medicine
Showa-machi, Maebashi, Gunma, , Japan
Countries
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References
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Kaira K, Oriuchi N, Shimizu K, Ishikita T, Higuchi T, Imai H, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Endou H, Nakajima T, Endo K, Mori M. Correlation of angiogenesis with 18F-FMT and 18F-FDG uptake in non-small cell lung cancer. Cancer Sci. 2009 Apr;100(4):753-8. doi: 10.1111/j.1349-7006.2008.01077.x. Epub 2009 Jan 12.
Other Identifiers
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kkaira1970
Identifier Type: -
Identifier Source: org_study_id
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