Safety and Tolerability of NOVA63035 "Corticosteroid" in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy

NCT ID: NCT00665106

Last Updated: 2015-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-04-30

Study Completion Date

2011-09-30

Brief Summary

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Evaluation of safety and tolerability of a single injection of NOVA63035 "Corticosteroid" administered at one of four doses in patients with diabetic macular edema (DME) secondary to diabetic retinopathy

Detailed Description

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Conditions

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Diabetic Macular Edema

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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cohort 1

5 up to 6 patients per arm. Emulsion at 0.8% of drug product.

Group Type EXPERIMENTAL

NOVA63035 "Corticosteroid"

Intervention Type DRUG

Single injection in the study eye

cohort 2

5 up to 6 patients per arm. Emulsion at 0.8% of drug product.

Group Type EXPERIMENTAL

NOVA63035 "Corticosteroid"

Intervention Type DRUG

Single injection in the study eye

cohort 3

5 up to 6 patients per arm. Emulsion at 3.2% of drug product.

Group Type EXPERIMENTAL

NOVA63035 "Corticosteroid"

Intervention Type DRUG

Single injection in the study eye

cohort 4

5 up to 6 patients per arm. Oily solution at 3.4% of drug product.

Group Type EXPERIMENTAL

NOVA63035 "Corticosteroid"

Intervention Type DRUG

Single injection in the study eye

Interventions

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NOVA63035 "Corticosteroid"

Single injection in the study eye

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* M \& F 18 years and older
* Diagnosed with diabetes mellitus and presenting diabetic retinopathy

Exclusion Criteria

* Monocular
* History of current ocular hypertension or glaucoma in either eye defined
* Any significant ocular disease (other than diabetic retinopathy)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Santen SAS

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Midwest Eye Institute

Indianapolis, Indiana, United States

Site Status

Countries

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United States

Other Identifiers

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NVG07D108

Identifier Type: -

Identifier Source: org_study_id

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