A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome
NCT ID: NCT00658515
Last Updated: 2020-01-03
Study Results
Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.
View full resultsBasic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE3
15871 participants
INTERVENTIONAL
2008-04-30
2012-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients
NCT00655538
A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.
NCT00353522
A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure
NCT01877915
Clinical and Economic Outcomes of Oral Anticoagulants in Non-valvular Atrial Fibrillation
NCT03087487
An Exploratory stuDy of effectIveneSs and Safety of rivarOxaban in Patients With Left VEntricular Thrombus (R-DISSOLVE)
NCT04970381
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Dalcetrapib (RO4607381)
Dalcetrapib (RO4607381)
600mg po daily
Evidence-based medical care for Acute Coronary Syndrome
As prescribed
Placebo
Evidence-based medical care for Acute Coronary Syndrome
As prescribed
Placebo
po daily
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Dalcetrapib (RO4607381)
600mg po daily
Evidence-based medical care for Acute Coronary Syndrome
As prescribed
Placebo
po daily
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* recently hospitalized for ACS;
* clinically stable;
* receiving evidence-based medical and dietary management of dyslipidemia.
Exclusion Criteria
* clinically unstable;
* severe anemia;
* uncontrolled hypertension;
* concomitant treatment with any other drug raising HDL-C (eg niacin, fibrates).
45 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Hoffmann-La Roche
INDUSTRY
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Clinical Trials
Role: STUDY_DIRECTOR
Hoffmann-La Roche
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Laval, Quebec, Canada
Birmingham, Alabama, United States
Birmingham, Alabama, United States
Birmingham, Alabama, United States
Birmingham, Alabama, United States
Mobile, Alabama, United States
Tuscaloosa, Alabama, United States
Lake Havasu City, Arizona, United States
Mesa, Arizona, United States
Phoenix, Arizona, United States
Phoenix, Arizona, United States
Scottsdale, Arizona, United States
Scottsdale, Arizona, United States
Sierra Vista, Arizona, United States
Tempe, Arizona, United States
Tucson, Arizona, United States
Hot Springs, Arkansas, United States
Jonesboro, Arkansas, United States
Little Rock, Arkansas, United States
Mountain Home, Arkansas, United States
Searcy, Arkansas, United States
Anaheim, California, United States
Bakersfield, California, United States
Bellflower, California, United States
Beverly Hills, California, United States
Buena Park, California, United States
Burbank, California, United States
Carmichael, California, United States
Corona, California, United States
Costa Mesa, California, United States
Encinitas, California, United States
Fountain Valley, California, United States
Fresno, California, United States
Fresno, California, United States
Fullerton, California, United States
Glendale, California, United States
Glendale, California, United States
Hawaiian Gardens, California, United States
Hollywood, California, United States
Inglewood, California, United States
La Jolla, California, United States
La Mesa, California, United States
Laguna Hills, California, United States
Loma Linda, California, United States
Lomita, California, United States
Long Beach, California, United States
Los Alamitos, California, United States
Los Angeles, California, United States
Los Angeles, California, United States
Los Angeles, California, United States
Los Angeles, California, United States
Los Banos, California, United States
Mather, California, United States
Mission Viejo, California, United States
Mountain View, California, United States
Newport Beach, California, United States
Newport Beach, California, United States
Pasadena, California, United States
Pomona, California, United States
Redondo Beach, California, United States
Sacramento, California, United States
Sacramento, California, United States
Sacramento, California, United States
San Diego, California, United States
San Diego, California, United States
San Diego, California, United States
San Dimas, California, United States
San Francisco, California, United States
San Francisco, California, United States
San Jose, California, United States
Santa Ana, California, United States
Santa Rosa, California, United States
Simi Valley, California, United States
Stockton, California, United States
Stockton, California, United States
Thousand Oaks, California, United States
Torrance, California, United States
Whittier, California, United States
Colorado Springs, Colorado, United States
Colorado Springs, Colorado, United States
Denver, Colorado, United States
Denver, Colorado, United States
Greeley, Colorado, United States
Littleton, Colorado, United States
Loveland, Colorado, United States
Pueblo, Colorado, United States
Bridgeport, Connecticut, United States
Danbury, Connecticut, United States
Guilford, Connecticut, United States
Hartford, Connecticut, United States
Stamford, Connecticut, United States
Washington D.C., District of Columbia, United States
Washington D.C., District of Columbia, United States
Aventura, Florida, United States
Boynton Beach, Florida, United States
Chipley, Florida, United States
Clearwater, Florida, United States
Clearwater, Florida, United States
Crystal River, Florida, United States
Daytona Beach, Florida, United States
Daytona Beach, Florida, United States
Deerfield Beach, Florida, United States
Delray Beach, Florida, United States
Delray Beach, Florida, United States
Elizabeth, Florida, United States
Fort Lauderdale, Florida, United States
Gainesville, Florida, United States
Gainesville, Florida, United States
Gainesville, Florida, United States
Hollywood, Florida, United States
Hudson, Florida, United States
Jacksonville, Florida, United States
Jacksonville, Florida, United States
Jacksonville, Florida, United States
Jacksonville Beach, Florida, United States
Jupiter, Florida, United States
Kissimmee, Florida, United States
Lakeland, Florida, United States
Marianna, Florida, United States
Melbourne, Florida, United States
Miami, Florida, United States
Miami, Florida, United States
Miami, Florida, United States
Ocala, Florida, United States
Orlando, Florida, United States
Panama City, Florida, United States
Pensacola, Florida, United States
Pensacola, Florida, United States
Plantation, Florida, United States
Port Charlotte, Florida, United States
Safety Harbor, Florida, United States
Sarasota, Florida, United States
St. Petersburg, Florida, United States
St. Petersburg, Florida, United States
Tallahassee, Florida, United States
Tamarac, Florida, United States
Tampa, Florida, United States
Tampa, Florida, United States
Tampa, Florida, United States
Tampa, Florida, United States
West Palm Beach, Florida, United States
West Palm Beach, Florida, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Atlanta, Georgia, United States
Columbus, Georgia, United States
Covington, Georgia, United States
Decatur, Georgia, United States
Monroe, Georgia, United States
Riverdale, Georgia, United States
Savannah, Georgia, United States
Tucker, Georgia, United States
Waycross, Georgia, United States
Honolulu, Hawaii, United States
Boise, Idaho, United States
Aurora, Illinois, United States
Bannockburn, Illinois, United States
Chicago, Illinois, United States
Evanston, Illinois, United States
Gurnee, Illinois, United States
Hinsdale, Illinois, United States
Joliet, Illinois, United States
Libertyville, Illinois, United States
Melrose Park, Illinois, United States
Mokena, Illinois, United States
Naperville, Illinois, United States
Normal, Illinois, United States
Peoria, Illinois, United States
Peoria, Illinois, United States
Rockford, Illinois, United States
Winfield, Illinois, United States
Anderson, Indiana, United States
Elkhart, Indiana, United States
Evansville, Indiana, United States
Fishers, Indiana, United States
Fort Wayne, Indiana, United States
Franklin, Indiana, United States
Greenfield, Indiana, United States
Hammond, Indiana, United States
Indianapolis, Indiana, United States
Indianapolis, Indiana, United States
Indianapolis, Indiana, United States
Indianapolis, Indiana, United States
Indianapolis, Indiana, United States
Merrillville, Indiana, United States
Munster, Indiana, United States
South Bend, Indiana, United States
Ames, Iowa, United States
Council Bluffs, Iowa, United States
Davenport, Iowa, United States
Waterloo, Iowa, United States
Olathe, Kansas, United States
Overland Park, Kansas, United States
Elizabethtown, Kentucky, United States
Hazard, Kentucky, United States
Lexington, Kentucky, United States
Lexington, Kentucky, United States
Lexington, Kentucky, United States
Louisville, Kentucky, United States
Louisville, Kentucky, United States
Madisonville, Kentucky, United States
Owensboro, Kentucky, United States
Alexandria, Louisiana, United States
Lake Charles, Louisiana, United States
Marrero, Louisiana, United States
Metairie, Louisiana, United States
Natchitoches, Louisiana, United States
New Orleans, Louisiana, United States
New Orleans, Louisiana, United States
Shreveport, Louisiana, United States
Slidell, Louisiana, United States
West Monroe, Louisiana, United States
Bangor, Maine, United States
Biddeford, Maine, United States
Portland, Maine, United States
Scarborough, Maine, United States
South Portland, Maine, United States
Baltimore, Maryland, United States
Baltimore, Maryland, United States
Baltimore, Maryland, United States
Baltimore, Maryland, United States
Baltimore, Maryland, United States
Baltimore, Maryland, United States
Bel Air, Maryland, United States
Columbia, Maryland, United States
Hagerstown, Maryland, United States
Pikesville, Maryland, United States
Salisbury, Maryland, United States
Towson, Maryland, United States
Towson, Maryland, United States
Westminster, Maryland, United States
Billerica, Massachusetts, United States
Boston, Massachusetts, United States
Boston, Massachusetts, United States
East Bridgewater, Massachusetts, United States
Haverhill, Massachusetts, United States
Hyannis, Massachusetts, United States
Natick, Massachusetts, United States
North Dartmouth, Massachusetts, United States
Pittsfield, Massachusetts, United States
Springfield, Massachusetts, United States
Taunton, Massachusetts, United States
Worcester, Massachusetts, United States
Worcester, Massachusetts, United States
Alpena, Michigan, United States
Ann Arbor, Michigan, United States
Bloomfield, Michigan, United States
Cadillac, Michigan, United States
Dearborn, Michigan, United States
Detroit, Michigan, United States
Detroit, Michigan, United States
Fairfield, Michigan, United States
Flint, Michigan, United States
Flint, Michigan, United States
Kalamazoo, Michigan, United States
Kalamazoo, Michigan, United States
Lansing, Michigan, United States
Lansing, Michigan, United States
Midland, Michigan, United States
Milwaukee, Michigan, United States
Petoskey, Michigan, United States
Rochester Hills, Michigan, United States
Saginaw, Michigan, United States
Saint Joseph, Michigan, United States
Chaska, Minnesota, United States
Duluth, Minnesota, United States
Duluth, Minnesota, United States
Minneapolis, Minnesota, United States
Minneapolis, Minnesota, United States
Minneapolis, Minnesota, United States
Robbinsdale, Minnesota, United States
Rochester, Minnesota, United States
Saint Cloud, Minnesota, United States
Saint Paul, Minnesota, United States
Gulfport, Mississippi, United States
Jackson, Mississippi, United States
Picayune, Mississippi, United States
Tupelo, Mississippi, United States
Columbia, Missouri, United States
Kansas City, Missouri, United States
St Louis, Missouri, United States
St Louis, Missouri, United States
Billings, Montana, United States
Great Falls, Montana, United States
Kalispell, Montana, United States
Missoula, Montana, United States
Fremont, Nebraska, United States
Grand Island, Nebraska, United States
Lincoln, Nebraska, United States
Omaha, Nebraska, United States
Papillion, Nebraska, United States
Las Vegas, Nevada, United States
Las Vegas, Nevada, United States
Reno, Nevada, United States
Manchester, New Hampshire, United States
Nashua, New Hampshire, United States
Bridgewater, New Jersey, United States
Clifton, New Jersey, United States
East Orange, New Jersey, United States
Edgewater, New Jersey, United States
Elmer, New Jersey, United States
Greenville, New Jersey, United States
Hackensack, New Jersey, United States
Haddon Heights, New Jersey, United States
Hawthorne, New Jersey, United States
Linden, New Jersey, United States
Mine Hill, New Jersey, United States
New Brunswick, New Jersey, United States
Newark, New Jersey, United States
Ridgewood, New Jersey, United States
Sewell, New Jersey, United States
Somerset, New Jersey, United States
Summit, New Jersey, United States
Toms River, New Jersey, United States
Voorhees Township, New Jersey, United States
Westwood, New Jersey, United States
Albuquerque, New Mexico, United States
Albany, New York, United States
Brooklyn, New York, United States
Brooklyn, New York, United States
Brooklyn, New York, United States
Brooklyn, New York, United States
Buffalo, New York, United States
Buffalo, New York, United States
Fishkill, New York, United States
Flushing, New York, United States
Johnson City, New York, United States
Liverpool, New York, United States
New Hartford, New York, United States
New Windsor, New York, United States
New York, New York, United States
New York, New York, United States
New York, New York, United States
New York, New York, United States
Poughkeepsie, New York, United States
Rochester, New York, United States
Rochester, New York, United States
Saratoga Springs, New York, United States
Springfield Gardens, New York, United States
Stony Brook, New York, United States
Suffern, New York, United States
Syracuse, New York, United States
The Bronx, New York, United States
The Bronx, New York, United States
Troy, New York, United States
West Seneca, New York, United States
Asheville, North Carolina, United States
Cary, North Carolina, United States
Chapel Hill, North Carolina, United States
Charlotte, North Carolina, United States
Charlotte, North Carolina, United States
Concord, North Carolina, United States
Durham, North Carolina, United States
Durham, North Carolina, United States
Elizabeth City, North Carolina, United States
Pinehurst, North Carolina, United States
Rocky Mount, North Carolina, United States
Salt Lake City, North Carolina, United States
Tabor City, North Carolina, United States
Wilmington, North Carolina, United States
Winston-Salem, North Carolina, United States
Fargo, North Dakota, United States
Minot, North Dakota, United States
Akron, Ohio, United States
Akron, Ohio, United States
Athens, Ohio, United States
Canton, Ohio, United States
Centerville, Ohio, United States
Cincinnati, Ohio, United States
Cincinnati, Ohio, United States
Cleveland, Ohio, United States
Columbus, Ohio, United States
Kettering, Ohio, United States
Mansfield, Ohio, United States
Marion, Ohio, United States
Mentor, Ohio, United States
Middletown, Ohio, United States
Sandusky, Ohio, United States
Springfield, Ohio, United States
Thornville, Ohio, United States
Toledo, Ohio, United States
Toledo, Ohio, United States
Toledo, Ohio, United States
Westlake, Ohio, United States
Willoughby Hills, Ohio, United States
Zanesville, Ohio, United States
Bartlesville, Oklahoma, United States
Midwest City, Oklahoma, United States
Oklahoma City, Oklahoma, United States
Oklahoma City, Oklahoma, United States
Oklahoma City, Oklahoma, United States
Bend, Oregon, United States
Portland, Oregon, United States
Abington, Pennsylvania, United States
Allentown, Pennsylvania, United States
Altoona, Pennsylvania, United States
Beaver, Pennsylvania, United States
Bryn Mawr, Pennsylvania, United States
Camp Hill, Pennsylvania, United States
Downingtown, Pennsylvania, United States
Doylestown, Pennsylvania, United States
Easton, Pennsylvania, United States
Erie, Pennsylvania, United States
Feasterville, Pennsylvania, United States
Havertown, Pennsylvania, United States
Hershey, Pennsylvania, United States
Lancaster, Pennsylvania, United States
Langhorne, Pennsylvania, United States
Limerick, Pennsylvania, United States
Natrona Heights, Pennsylvania, United States
North Wales, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pottstown, Pennsylvania, United States
Sayre, Pennsylvania, United States
Scranton, Pennsylvania, United States
Sellersville, Pennsylvania, United States
West Chester, Pennsylvania, United States
Wormleysburg, Pennsylvania, United States
Wynnewood, Pennsylvania, United States
Wyomissing, Pennsylvania, United States
Providence, Rhode Island, United States
Providence, Rhode Island, United States
Wakefield, Rhode Island, United States
Aiken, South Carolina, United States
Charleston, South Carolina, United States
Charleston, South Carolina, United States
Columbia, South Carolina, United States
Greer, South Carolina, United States
Moncks Corner, South Carolina, United States
Spartanburg, South Carolina, United States
Spartanburg, South Carolina, United States
Taylors, South Carolina, United States
Knoxville, South Dakota, United States
Rapid City, South Dakota, United States
Sioux Falls, South Dakota, United States
Bristol, Tennessee, United States
Jackson, Tennessee, United States
Johnson City, Tennessee, United States
Kingsport, Tennessee, United States
Knoxville, Tennessee, United States
Knoxville, Tennessee, United States
Lexington, Tennessee, United States
Oak Ridge, Tennessee, United States
Austin, Texas, United States
Austin, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Fort Worth, Texas, United States
Houston, Texas, United States
Houston, Texas, United States
Houston, Texas, United States
Houston, Texas, United States
Humble, Texas, United States
Killeen, Texas, United States
Lubbock, Texas, United States
Odessa, Texas, United States
Plano, Texas, United States
Round Rock, Texas, United States
San Antonio, Texas, United States
San Antonio, Texas, United States
Tomball, Texas, United States
Tyler, Texas, United States
Tyler, Texas, United States
Victoria, Texas, United States
Layton, Utah, United States
Provo, Utah, United States
Burke, Virginia, United States
Charlottesville, Virginia, United States
Colonial Heights, Virginia, United States
Danville, Virginia, United States
Danville, Virginia, United States
Falls Church, Virginia, United States
Falls Church, Virginia, United States
Galax, Virginia, United States
Hopewell, Virginia, United States
Manassas, Virginia, United States
Midlothian, Virginia, United States
Norfolk, Virginia, United States
Norfolk, Virginia, United States
Richmond, Virginia, United States
Richmond, Virginia, United States
Roanoke, Virginia, United States
Salem, Virginia, United States
Springfield, Virginia, United States
Winchester, Virginia, United States
Bellevue, Washington, United States
Everett, Washington, United States
Monroe, Washington, United States
Selah, Washington, United States
Spokane, Washington, United States
Clarksburg, West Virginia, United States
Beloit, Wisconsin, United States
Burlington, Wisconsin, United States
Green Bay, Wisconsin, United States
Green Bay, Wisconsin, United States
La Crosse, Wisconsin, United States
Madison, Wisconsin, United States
Madison, Wisconsin, United States
Madison, Wisconsin, United States
Marshfield, Wisconsin, United States
Milwaukee, Wisconsin, United States
Milwaukee, Wisconsin, United States
Almirante Brown, , Argentina
Bahía Blanca, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Buenos Aires, , Argentina
CABA, , Argentina
Capital Federal, , Argentina
Cipolletti, , Argentina
Ciudad Autonoma Bs As, , Argentina
Ciudad Autónoma de Bs. As., , Argentina
Coronel Suárez, , Argentina
Corrientes, , Argentina
Córdoba, , Argentina
Córdoba, , Argentina
Córdoba, , Argentina
Junín, , Argentina
La Plata, , Argentina
Mar del Plata, , Argentina
Mar del Plata, , Argentina
Mendoza, , Argentina
Quilmes, , Argentina
Rosario, , Argentina
Rosario, , Argentina
Salta, , Argentina
San Isidro, , Argentina
San Justo, , Argentina
San Martín, , Argentina
San Miguel de Tucumán, , Argentina
San Salvador de Jujuy, , Argentina
Santa Fe, , Argentina
Garran, Australian Capital Territory, Australia
Coffs Harbour, New South Wales, Australia
Concord, New South Wales, Australia
Epping, New South Wales, Australia
Kingswood, New South Wales, Australia
Wollongong, New South Wales, Australia
Cairns, Queensland, Australia
Chermside, Queensland, Australia
Milton, Queensland, Australia
Woolloongabba, Queensland, Australia
Bedford Park, South Australia, Australia
Box Hill, Victoria, Australia
Geelong, Victoria, Australia
Sale, Victoria, Australia
Joondalup, Western Australia, Australia
Nedlands, Western Australia, Australia
Feldkirch, , Austria
Graz, , Austria
Graz, , Austria
Linz, , Austria
Vienna, , Austria
Vienna, , Austria
Vienna, , Austria
Aalst, , Belgium
Bruges, , Belgium
Brussels, , Belgium
Brussels, , Belgium
Genk, , Belgium
Ghent, , Belgium
La Louvière, , Belgium
Roeselare, , Belgium
Tienen, , Belgium
Maceió, Alagoas, Brazil
Fortaleza, Ceará, Brazil
Salvador, Estado de Bahia, Brazil
Goiânia, Goiás, Brazil
Campo Grande, Mato Grosso do Sul, Brazil
Belo Horizonte, Minas Gerais, Brazil
Belo Horizonte, Minas Gerais, Brazil
Belo Horizonte, Minas Gerais, Brazil
Belo Horizonte, Minas Gerais, Brazil
Belo Horizonte, Minas Gerais, Brazil
Uberlândia, Minas Gerais, Brazil
Campina Grande do Sul, Paraná, Brazil
Curitiba, Paraná, Brazil
Curitiba, Paraná, Brazil
Olinda, Pernambuco, Brazil
Recife, Pernambuco, Brazil
Recife, Pernambuco, Brazil
Rio de Janeiro, Rio de Janeiro, Brazil
Rio de Janeiro, Rio de Janeiro, Brazil
Rio de Janeiro, Rio de Janeiro, Brazil
Natal, Rio Grande do Norte, Brazil
Pelotas, Rio Grande do Sul, Brazil
Porto Alegre, Rio Grande do Sul, Brazil
Porto Alegre, Rio Grande do Sul, Brazil
Porto Alegre, Rio Grande do Sul, Brazil
Porto Alegre, Rio Grande do Sul, Brazil
Porto Alegre, Rio Grande do Sul, Brazil
Sao Jose Do Rio Preto, Santa Catarina, Brazil
Sao Jose Do Rio Preto, Santa Catarina, Brazil
Aracaju, Sergipe, Brazil
Campinas, São Paulo, Brazil
Ribeirão Preto, São Paulo, Brazil
Santo André, São Paulo, Brazil
São José do Rio Preto, São Paulo, Brazil
São Paulo, São Paulo, Brazil
São Paulo, São Paulo, Brazil
São Paulo, São Paulo, Brazil
São Paulo, São Paulo, Brazil
São Paulo, São Paulo, Brazil
Calgary, Alberta, Canada
Edmonton, Alberta, Canada
Edmonton, Alberta, Canada
Nanaimo, British Columbia, Canada
New Westminster, British Columbia, Canada
Surrey, British Columbia, Canada
Vancouver, British Columbia, Canada
Vancouver, British Columbia, Canada
Victoria, British Columbia, Canada
Winnipeg, Manitoba, Canada
Winnipeg, Manitoba, Canada
Moncton, New Brunswick, Canada
Mount Pearl, Newfoundland and Labrador, Canada
St. John's, Newfoundland and Labrador, Canada
St. John's, Newfoundland and Labrador, Canada
St. John's, Newfoundland and Labrador, Canada
Halifax, Nova Scotia, Canada
Ajax, Ontario, Canada
Brampton, Ontario, Canada
Burlington, Ontario, Canada
Cambridge, Ontario, Canada
Cambridge, Ontario, Canada
Greater Sudbury, Ontario, Canada
Greater Sudbury, Ontario, Canada
Hamilton, Ontario, Canada
Kingston, Ontario, Canada
Kitchener, Ontario, Canada
Kitchener, Ontario, Canada
Mississauga, Ontario, Canada
Newmarket, Ontario, Canada
Oshawa, Ontario, Canada
Ottawa, Ontario, Canada
Thunder Bay, Ontario, Canada
Thunder Bay, Ontario, Canada
Toronto, Ontario, Canada
Toronto, Ontario, Canada
Toronto, Ontario, Canada
Toronto, Ontario, Canada
Gatineau, Quebec, Canada
Granby, Quebec, Canada
Greenfield Park, Quebec, Canada
Lachine, Quebec, Canada
Longueuil, Quebec, Canada
Montreal, Quebec, Canada
Montreal, Quebec, Canada
Montreal, Quebec, Canada
Montreal, Quebec, Canada
Montreal, Quebec, Canada
Montreal, Quebec, Canada
Montreal, Quebec, Canada
Québec, Quebec, Canada
Québec, Quebec, Canada
Québec, Quebec, Canada
Saint Georges-de-beauce, Quebec, Canada
Saint-Charles-Borromée, Quebec, Canada
Saint-Jérôme, Quebec, Canada
Saint-Lambert, Quebec, Canada
Saint-Léonard, Quebec, Canada
Sherbrooke, Quebec, Canada
Sherbrooke, Quebec, Canada
Sherbrooke, Quebec, Canada
Ste. Foy, Quebec, Canada
Terrebonne, Quebec, Canada
Trois-Rivières, Quebec, Canada
Trois-Rivières, Quebec, Canada
Val-d'Or, Quebec, Canada
Westmount, Quebec, Canada
Saskatoon, Saskatchewan, Canada
Beijing, , China
Beijing, , China
Beijing, , China
Beijing, , China
Beijing, , China
Beijing, , China
Beijing, , China
Changsha, , China
Dalian, , China
Daqing, , China
Guangzhou, , China
Guangzhou, , China
Hangzhou, , China
Hangzhou, , China
Hangzhou, , China
Harbin, , China
Jinan, , China
Lanzhou, , China
Lanzhou, , China
Nanchang, , China
Nanjing, , China
Nanjing, , China
Shanghai, , China
Shanghai, , China
Shanghai, , China
Shanghai, , China
Shenyang, , China
Shenyang, , China
Shijiazhuang, , China
Shijiazhuang, , China
Suzhou, , China
Suzhou, , China
Wenzhou, , China
Wuhan, , China
Wuhan, , China
Xi'an, , China
Brno, , Czechia
Chrudim, , Czechia
České Budějovice, , Czechia
Hradec Králové, , Czechia
Jihlava, , Czechia
Jindřichův Hradec, , Czechia
Karlovy Vary, , Czechia
Kroměříž, , Czechia
Náchod, , Czechia
Ostrava - Fifejdy, , Czechia
Pardubice, , Czechia
Prague, , Czechia
Prague, , Czechia
Prague, , Czechia
Prague, , Czechia
Prague, , Czechia
Semily, , Czechia
Slaný, , Czechia
Tábor, , Czechia
Teplice, , Czechia
Trutnov, , Czechia
Zlín, , Czechia
Znojmo, , Czechia
Frederiksberg, , Denmark
Hellerup, , Denmark
Herlev, , Denmark
Herning, , Denmark
Hillerød, , Denmark
Kolding, , Denmark
København S, , Denmark
Køge, , Denmark
Roskilde, , Denmark
Svendborg, , Denmark
Jyväskylä, , Finland
Kotka, , Finland
Kuopio, , Finland
Angers, , France
Bron, , France
Colmar, , France
Dijon, , France
Lille, , France
Marseille, , France
Marseille, , France
Montfermeil, , France
Paris, , France
Paris, , France
Paris, , France
Paris, , France
Paris, , France
Pessac, , France
Poitiers, , France
Roubaix, , France
Saint-Herblain, , France
Strasbourg, , France
Strasbourg, , France
Tourcoing, , France
Valenciennes, , France
Vandœuvre-lès-Nancy, , France
Bad Krozingen, , Germany
Bad Rothenfelde, , Germany
Bad Segeberg, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Bielefeld, , Germany
Bochum, , Germany
Bochum, , Germany
Burg, , Germany
Coburg, , Germany
Darmstadt, , Germany
Dortmund, , Germany
Duisburg, , Germany
Essen, , Germany
Frankfurt, , Germany
Frankfurt am Main, , Germany
Führt, , Germany
Halle, , Germany
Hamburg, , Germany
Heidelberg, , Germany
Homburg/Saar, , Germany
Langen, , Germany
Limburg, , Germany
Mainz, , Germany
Mannheim, , Germany
Mönchengladbach, , Germany
Neuss, , Germany
Northeim, , Germany
Rüdersdorf, , Germany
Ulm, , Germany
Villingen-Schwenningen, , Germany
Witten, , Germany
Wuppertal, , Germany
Toulouse, , Grenada
Baja, , Hungary
Békéscsaba, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Budapest, , Hungary
Debrecen, , Hungary
Kalocsa, , Hungary
Kecskemét, , Hungary
Pécs, , Hungary
Sopron, , Hungary
Szeged, , Hungary
Szekszárd, , Hungary
Székesfehérvár, , Hungary
Zalaegerszeg, , Hungary
Dublin, , Ireland
Dublin, , Ireland
Dublin, , Ireland
Afula, , Israel
Beersheba, , Israel
Giv‘atayim, , Israel
Hadera, , Israel
Haifa, , Israel
Haifa, , Israel
Haifa, , Israel
Haifa, , Israel
Jerusalem, , Israel
Jerusalem, , Israel
Jerusalem, , Israel
Kfar Saba, , Israel
Nahariya, , Israel
Nazareth, , Israel
Petah Tikva, , Israel
Petah Tikva, , Israel
Rehovot, , Israel
Tel Aviv, , Israel
Tel Aviv, , Israel
Tel Litwinsky, , Israel
Tiberias, , Israel
Ẕerifin, , Israel
Chieti, Abruzzo, Italy
Caserta, Campania, Italy
Napoli, Campania, Italy
Carpi, Emilia-Romagna, Italy
Forlì, Emilia-Romagna, Italy
Modena, Emilia-Romagna, Italy
Piacenza, Emilia-Romagna, Italy
Udine, Friuli Venezia Giulia, Italy
Rome, Lazio, Italy
Rome, Lazio, Italy
Genoa, Liguria, Italy
Bergamo, Lombardy, Italy
Como, Lombardy, Italy
Milan, Lombardy, Italy
Pavia, Lombardy, Italy
Rozzano, Lombardy, Italy
Novara, Piedmont, Italy
Turin, Piedmont, Italy
Pesaro, The Marches, Italy
Castelnuovo, Tuscany, Italy
S. Bonifacio, Veneto, Italy
Treviso, Veneto, Italy
's-Hertogenbosch, , Netherlands
Alkmaar, , Netherlands
Almelo, , Netherlands
Amersfoort, , Netherlands
Amstelveen, , Netherlands
Amsterdam, , Netherlands
Amsterdam, , Netherlands
Amsterdam, , Netherlands
Amsterdam, , Netherlands
Amsterdam, , Netherlands
Arnhem, , Netherlands
Blaricum, , Netherlands
Breda, , Netherlands
Capelle AD Yssel, , Netherlands
Delft, , Netherlands
Den Helder, , Netherlands
Deventer, , Netherlands
Eindhoven, , Netherlands
Enschede, , Netherlands
Goes, , Netherlands
Groningen, , Netherlands
Haarlem, , Netherlands
Heerlen, , Netherlands
Hengelo, , Netherlands
Hilversum, , Netherlands
Hoofddorp, , Netherlands
Hoorn, , Netherlands
Leiden, , Netherlands
Leiderdorp, , Netherlands
Maastricht, , Netherlands
Nieuwegein, , Netherlands
Nijmegen, , Netherlands
Purmerend, , Netherlands
Rotterdam, , Netherlands
Rotterdam, , Netherlands
Rotterdam, , Netherlands
Sneek, , Netherlands
Stadskanaal, , Netherlands
Tilburg, , Netherlands
Tilburg, , Netherlands
Utrecht, , Netherlands
Weert, , Netherlands
Zaandam, , Netherlands
Zwolle, , Netherlands
Auckland, , New Zealand
Auckland, , New Zealand
Christchurch, , New Zealand
Dunedin, , New Zealand
Hamilton, , New Zealand
Nelson, , New Zealand
New Plymouth, , New Zealand
Wellington, , New Zealand
Bialystok, , Poland
Bydgoszcz, , Poland
Bydgoszcz, , Poland
Elblag, , Poland
Gdansk, , Poland
Gdynia, , Poland
Gdynia, , Poland
Grodzisk Mazowiecki, , Poland
Inowrocław, , Poland
Katowice, , Poland
Krakow, , Poland
Krakow, , Poland
Lodz, , Poland
Lodz, , Poland
Lublin, , Poland
Nowa Sól, , Poland
Poznan, , Poland
Poznan, , Poland
Puławy, , Poland
Płock, , Poland
Ruda Śląska, , Poland
Siedlce, , Poland
Sopot, , Poland
Sosnowiec, , Poland
Stalowa Wola, , Poland
Starachowice, , Poland
Szczecin, , Poland
Świdnik, , Poland
Tarnów, , Poland
Torun, , Poland
Warsaw, , Poland
Warsaw, , Poland
Warsaw, , Poland
Warsaw, , Poland
Warsaw, , Poland
Wałbrzych, , Poland
Wroclaw, , Poland
Wroclaw, , Poland
Wroclaw, , Poland
Zamość, , Poland
Zielona Góra, , Poland
Aguas Buenas, , Puerto Rico
Caguas, , Puerto Rico
Manatí, , Puerto Rico
Ponce, , Puerto Rico
Ponce, , Puerto Rico
Río Grande, , Puerto Rico
San Juan, , Puerto Rico
Toa Baja, , Puerto Rico
Banská Bystrica, , Slovakia
Bardejov, , Slovakia
Bratislava, , Slovakia
Bratislava, , Slovakia
Dolný Kubín, , Slovakia
Martin, , Slovakia
Nitra, , Slovakia
Rimavská Sobota, , Slovakia
Žilina, , Slovakia
Alberton, , South Africa
Bloemfontein, , South Africa
Boksburg, , South Africa
Durban, , South Africa
Durban, , South Africa
Johannesburg, , South Africa
Johannesburg, , South Africa
Johannesburg, , South Africa
Kuilsriver, , South Africa
Lyttelton, Pretoria, , South Africa
Panorama, , South Africa
Pinelands, , South Africa
Pretoria, , South Africa
Somerset West, , South Africa
Busan, , South Korea
Daegu, , South Korea
Daegu, , South Korea
Gangwon-Do, , South Korea
Gangwon-do, , South Korea
Gwangju, , South Korea
Gyeonggi-do, , South Korea
Gyeonggi-do, , South Korea
Incheon, , South Korea
Kyonggi-do, , South Korea
Seoul, , South Korea
Seoul, , South Korea
Seoul, , South Korea
Seoul, , South Korea
Seoul, , South Korea
Vitoria-Gasteiz, Alava, Spain
Sant Joan d'Alacant, Alicante, Spain
L'Hospitalet de Llobregat, Barcelona, Spain
Santander, Cantabria, Spain
Figueres, Girona, Spain
Santiago de Compostela, LA Coruña, Spain
Majadahonda, Madrid, Spain
Málaga, Malaga, Spain
Pamplona, Navarre, Spain
Vigo, Pontevedra, Spain
Seville, Sevilla, Spain
Alicante, , Spain
Almería, , Spain
Barcelona, , Spain
Guadalajara, , Spain
Lugo, , Spain
Madrid, , Spain
Madrid, , Spain
Madrid, , Spain
Tarragona, , Spain
Valencia, , Spain
Valladolid, , Spain
Falun, , Sweden
Gothenburg, , Sweden
Stockholm, , Sweden
Stockholm, , Sweden
Västerås, , Sweden
Fribourg, , Switzerland
Geneva, , Switzerland
Kreuzlingen, , Switzerland
Lucerne, , Switzerland
Lugano, , Switzerland
Münsterlingen, , Switzerland
Wolhusen, , Switzerland
Airdrie, , United Kingdom
Barnet, , United Kingdom
Belfast, , United Kingdom
Birmingham, , United Kingdom
Birmingham, , United Kingdom
Blackpool, , United Kingdom
Bradford, , United Kingdom
Cambridge, , United Kingdom
Chertsey, , United Kingdom
Edinburgh, , United Kingdom
Glasgow, , United Kingdom
Glasgow, , United Kingdom
Glasgow, , United Kingdom
Larbert, , United Kingdom
Leicester, , United Kingdom
London, , United Kingdom
London, , United Kingdom
Luton, , United Kingdom
Manchester, , United Kingdom
Middlesbrough, , United Kingdom
Middlesex, , United Kingdom
Nottingham, , United Kingdom
Nuneaton, , United Kingdom
Paisley, , United Kingdom
Peterborough, , United Kingdom
Stockport, , United Kingdom
Swansea, , United Kingdom
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Schwartz GG, Leiter LA, Ballantyne CM, Barter PJ, Black DM, Kallend D, Laghrissi-Thode F, Leitersdorf E, McMurray JJV, Nicholls SJ, Olsson AG, Preiss D, Shah PK, Tardif JC, Kittelson J. Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease. Diabetes Care. 2020 May;43(5):1077-1084. doi: 10.2337/dc19-2204. Epub 2020 Mar 6.
Salahuddin T, Kittelson J, Tardif JC, Shah PK, Olsson AG, Nicholls SJ, Leitersdorf E, Leiter LA, Kallend D, Black DM, Barter PJ, Ballantyne CM, Schwartz GG. Association of high-density lipoprotein particle concentration with cardiovascular risk following acute coronary syndrome: A case-cohort analysis of the dal-Outcomes trial. Am Heart J. 2020 Mar;221:60-66. doi: 10.1016/j.ahj.2019.12.003. Epub 2019 Dec 16.
Schwartz GG, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, McMurray JJV, Nicholls SJ, Olsson AG, Shah PK, Tardif JC, Kittelson J. Association of Lipoprotein(a) With Risk of Recurrent Ischemic Events Following Acute Coronary Syndrome: Analysis of the dal-Outcomes Randomized Clinical Trial. JAMA Cardiol. 2018 Feb 1;3(2):164-168. doi: 10.1001/jamacardio.2017.3833.
Pitts R, Gunzburger E, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, Nicholls SJ, Shah PK, Tardif JC, Olsson AG, McMurray JJ, Kittelson J, Schwartz GG. Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. J Am Heart Assoc. 2017 Jan 10;6(1):e004119. doi: 10.1161/JAHA.116.004119.
Tardif JC, Rhainds D, Brodeur M, Feroz Zada Y, Fouodjio R, Provost S, Boule M, Alem S, Gregoire JC, L'Allier PL, Ibrahim R, Guertin MC, Mongrain I, Olsson AG, Schwartz GG, Rheaume E, Dube MP. Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation: Concordance With Clinical Outcomes. Circ Cardiovasc Genet. 2016 Aug;9(4):340-8. doi: 10.1161/CIRCGENETICS.116.001405. Epub 2016 Jul 14.
Schwartz GG, Abt M, Bao W, DeMicco D, Kallend D, Miller M, Mundl H, Olsson AG. Fasting triglycerides predict recurrent ischemic events in patients with acute coronary syndrome treated with statins. J Am Coll Cardiol. 2015 Jun 2;65(21):2267-75. doi: 10.1016/j.jacc.2015.03.544.
Tardif JC, Rheaume E, Lemieux Perreault LP, Gregoire JC, Feroz Zada Y, Asselin G, Provost S, Barhdadi A, Rhainds D, L'Allier PL, Ibrahim R, Upmanyu R, Niesor EJ, Benghozi R, Suchankova G, Laghrissi-Thode F, Guertin MC, Olsson AG, Mongrain I, Schwartz GG, Dube MP. Pharmacogenomic determinants of the cardiovascular effects of dalcetrapib. Circ Cardiovasc Genet. 2015 Apr;8(2):372-82. doi: 10.1161/CIRCGENETICS.114.000663. Epub 2015 Jan 11.
Schwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, Chaitman BR, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Mundl H, Nicholls SJ, Shah PK, Tardif JC, Wright RS; dal-OUTCOMES Investigators. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012 Nov 29;367(22):2089-99. doi: 10.1056/NEJMoa1206797. Epub 2012 Nov 5.
Luscher TF, Taddei S, Kaski JC, Jukema JW, Kallend D, Munzel T, Kastelein JJ, Deanfield JE; dal-VESSEL Investigators. Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial. Eur Heart J. 2012 Apr;33(7):857-65. doi: 10.1093/eurheartj/ehs019. Epub 2012 Feb 16.
Derks M, Abt M, Parr G, Meneses-Lorente G, Young AM, Phelan M. No clinically relevant drug-drug interactions when dalcetrapib is co-administered with atorvastatin. Expert Opin Investig Drugs. 2010 Oct;19(10):1135-45. doi: 10.1517/13543784.2010.509342.
Schwartz GG, Olsson AG, Ballantyne CM, Barter PJ, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Shah PK, Tardif JC, Chaitman BR, Duttlinger-Maddux R, Mathieson J; dal-OUTCOMES Committees and Investigators. Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome. Am Heart J. 2009 Dec;158(6):896-901.e3. doi: 10.1016/j.ahj.2009.09.017.
Stein EA, Stroes ES, Steiner G, Buckley BM, Capponi AM, Burgess T, Niesor EJ, Kallend D, Kastelein JJ. Safety and tolerability of dalcetrapib. Am J Cardiol. 2009 Jul 1;104(1):82-91. doi: 10.1016/j.amjcard.2009.02.061.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2007-005103-18
Identifier Type: -
Identifier Source: secondary_id
NC20971
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.