Trial Outcomes & Findings for A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome (NCT NCT00658515)
NCT ID: NCT00658515
Last Updated: 2020-01-03
Results Overview
Number of cardiovascular events per patient per year
Recruitment status
COMPLETED
Study phase
PHASE3
Target enrollment
15871 participants
Primary outcome timeframe
From date of randomization to first event up to 48 months
Results posted on
2020-01-03
Participant Flow
Participant milestones
| Measure |
Dalcetrapib (RO4607381)
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
|---|---|---|
|
Overall Study
STARTED
|
7938
|
7933
|
|
Overall Study
COMPLETED
|
7626
|
7668
|
|
Overall Study
NOT COMPLETED
|
312
|
265
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome
Baseline characteristics by cohort
| Measure |
Dalcetrapib (RO4607381)
n=7938 Participants
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
n=7933 Participants
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
Total
n=15871 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
60.3 years
STANDARD_DEVIATION 9.09 • n=5 Participants
|
60.1 years
STANDARD_DEVIATION 9.10 • n=7 Participants
|
60.2 years
STANDARD_DEVIATION 9.10 • n=5 Participants
|
|
Sex: Female, Male
Female
|
6365 Participants
n=5 Participants
|
6436 Participants
n=7 Participants
|
12801 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
1573 Participants
n=5 Participants
|
1497 Participants
n=7 Participants
|
3070 Participants
n=5 Participants
|
PRIMARY outcome
Timeframe: From date of randomization to first event up to 48 monthsNumber of cardiovascular events per patient per year
Outcome measures
| Measure |
Dalcetrapib (RO4607381)
n=7938 Participants
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
n=7933 Participants
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
|---|---|---|
|
Incidence of Cardiovascular Mortality and Morbidity
|
0.034050 Event per Patient Years of Followup
|
0.032759 Event per Patient Years of Followup
|
SECONDARY outcome
Timeframe: Throughout Study, up to 53 MonthsOutcome measures
| Measure |
Dalcetrapib (RO4607381)
n=7938 Participants
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
n=7933 Participants
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
|---|---|---|
|
Composite Endpoint:All Cause Mortality
|
226 Participants
|
229 Participants
|
SECONDARY outcome
Timeframe: At 53 MonthsOutcome measures
| Measure |
Dalcetrapib (RO4607381)
n=7938 Participants
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
n=7933 Participants
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
|---|---|---|
|
Change From Baseline for HDL Cholesterol
|
44.96 mg/dL
Standard Error 4.133
|
15.60 mg/dL
Standard Error 4.102
|
SECONDARY outcome
Timeframe: Throughout Study, up to 53 MonthsPopulation: Data not collected
Outcome measures
Outcome data not reported
Adverse Events
Dalcetrapib (RO4607381)
Serious events: 1688 serious events
Other events: 4487 other events
Deaths: 0 deaths
Placebo
Serious events: 1692 serious events
Other events: 4297 other events
Deaths: 0 deaths
Serious adverse events
| Measure |
Dalcetrapib (RO4607381)
n=7938 participants at risk
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
n=7933 participants at risk
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
|---|---|---|
|
Infections and infestations
Peritoneal Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Peritonsillar Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Pharyngeal Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Pleurisy Viral
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Pneumococcal Infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Pneumonia Influenzal
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Pneumonia Legionella
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Pneumonia Viral
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Post Procedural Infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Postoperative Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Pulmonary Tuberculosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Rectal Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Respiratory Moniliasis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Scrub Typhus
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Septic Encephalopathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Soft Tissue Infection
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Staphylococcal Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Staphylococcal Sepsis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Staphylococcal Skin Infection
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Streptococcal Bacteremia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Angina Pectoris
|
1.4%
114/7938
|
1.5%
116/7933
|
|
Cardiac disorders
Atrial Fibrillation
|
0.87%
69/7938
|
0.97%
77/7933
|
|
Cardiac disorders
Angina Unstable
|
0.62%
49/7938
|
0.49%
39/7933
|
|
Cardiac disorders
Ventricular Tachycardia
|
0.23%
18/7938
|
0.20%
16/7933
|
|
Cardiac disorders
Atrial Flutter
|
0.09%
7/7938
|
0.16%
13/7933
|
|
Cardiac disorders
Coronary Artery Disease
|
0.14%
11/7938
|
0.10%
8/7933
|
|
Cardiac disorders
Sick Sinus Syndrome
|
0.10%
8/7938
|
0.13%
10/7933
|
|
Cardiac disorders
Bradycardia
|
0.08%
6/7938
|
0.10%
8/7933
|
|
Cardiac disorders
Ischemia Cardiomyopathy
|
0.10%
8/7938
|
0.06%
5/7933
|
|
Cardiac disorders
Aortic Valve Stenosis
|
0.06%
5/7938
|
0.06%
5/7933
|
|
Cardiac disorders
Palpitations
|
0.05%
4/7938
|
0.08%
6/7933
|
|
Cardiac disorders
Arrhythmia
|
0.05%
4/7938
|
0.06%
5/7933
|
|
Cardiac disorders
Atrioventricular Block Complete
|
0.06%
5/7938
|
0.05%
4/7933
|
|
Cardiac disorders
Myocardial Ischemia
|
0.06%
5/7938
|
0.05%
4/7933
|
|
Cardiac disorders
Supraventricular Tachycardia
|
0.06%
5/7938
|
0.05%
4/7933
|
|
Cardiac disorders
Ventricular Extrasystole
|
0.04%
3/7938
|
0.06%
5/7933
|
|
Cardiac disorders
Mitral Valve Incomplete
|
0.06%
5/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Atrial Tachicardia
|
0.05%
4/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Atrioventricular Block Second Degreee
|
0.01%
1/7938
|
0.05%
4/7933
|
|
Cardiac disorders
Cariogenic Shock
|
0.03%
2/7938
|
0.04%
3/7933
|
|
Cardiac disorders
Pericardial Effusion
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Prinzmetal Angina
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Sinus Bradycardia
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Sinus Tachycardia
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Tachyarrhythmia
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Tachycardia
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Bradyarrhythmia
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Dressler's Syndrome
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Left Ventricular Dysfunction
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Pericarditis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Aortic Valve Incompetence
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Arteriospasm Coronary
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Cardiac Discomfort
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Cardiac Tamponade
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Intracardiac Thrombus
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Rhythm Idioventricular
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Sinus Arrest
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Cardiac disorders
Sinus Arrhythmia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Ventricular Hypokinesia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Acute Coronary Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Aortic Valve Disease
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Aortic Valve Disease Mixed
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Arrhythmia Supraventricular
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Brugada Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Bundle Branch Block Right
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Cardiac Arrest
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Cardiac Asthma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Cardiac Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Cardiac Pseudoaneurism
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Cardiomyopathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Conduction Disorder
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Coronary Artery Dissection
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Coronary Artery Insufficiency
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Long QT Syndrome
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Mitral Valve Disease
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Mitral Valve Prolapse
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Pericardial Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Cardiac disorders
Tricuspid Valve Incompetence
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Ventricular Arrhythmia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Ventricular Fibrillation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Cardiac disorders
Ventricular Tachyarrhythmia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Pneumonia
|
0.81%
64/7938
|
0.91%
72/7933
|
|
Infections and infestations
Cellulitis
|
0.28%
22/7938
|
0.28%
22/7933
|
|
Infections and infestations
Appendicitis
|
0.18%
14/7938
|
0.25%
20/7933
|
|
Infections and infestations
Urinary Tract Infection
|
0.15%
12/7938
|
0.26%
21/7933
|
|
Infections and infestations
Gastroenteritis
|
0.16%
13/7938
|
0.15%
12/7933
|
|
Infections and infestations
Diverticulitis
|
0.13%
10/7938
|
0.14%
11/7933
|
|
Infections and infestations
Bronchitis
|
0.09%
7/7938
|
0.15%
12/7933
|
|
Infections and infestations
Erysipelas
|
0.04%
3/7938
|
0.13%
10/7933
|
|
Infections and infestations
Sepsis
|
0.10%
8/7938
|
0.05%
4/7933
|
|
Infections and infestations
Urosepsis
|
0.06%
5/7938
|
0.08%
6/7933
|
|
Infections and infestations
Wound Infection
|
0.04%
3/7938
|
0.08%
6/7933
|
|
Infections and infestations
Septic Shock
|
0.03%
2/7938
|
0.08%
6/7933
|
|
Infections and infestations
Upper Respiratory Tract Infection
|
0.06%
5/7938
|
0.04%
3/7933
|
|
Infections and infestations
Appendicitis Perforated
|
0.04%
3/7938
|
0.05%
4/7933
|
|
Infections and infestations
Bronchopneumonia
|
0.06%
5/7938
|
0.03%
2/7933
|
|
Infections and infestations
Herpes Zoster
|
0.03%
2/7938
|
0.06%
5/7933
|
|
Infections and infestations
Infective Exacerbation of Chronic Obstructive Airways Disease
|
0.05%
4/7938
|
0.04%
3/7933
|
|
Infections and infestations
Respiratory Tract Infection
|
0.04%
3/7938
|
0.05%
4/7933
|
|
Infections and infestations
Viral Infection
|
0.01%
1/7938
|
0.08%
6/7933
|
|
Infections and infestations
Anal Abscess
|
0.04%
3/7938
|
0.04%
3/7933
|
|
Infections and infestations
Gangrene
|
0.04%
3/7938
|
0.04%
3/7933
|
|
Infections and infestations
Lower Respiratory Tract Infection
|
0.06%
5/7938
|
0.01%
1/7933
|
|
Infections and infestations
Lung Infection
|
0.03%
2/7938
|
0.05%
4/7933
|
|
Infections and infestations
Osteomyelitis
|
0.01%
1/7938
|
0.06%
5/7933
|
|
Infections and infestations
Pyelonephritis
|
0.04%
3/7938
|
0.04%
3/7933
|
|
Infections and infestations
Sinusitis
|
0.03%
2/7938
|
0.04%
3/7933
|
|
Infections and infestations
Staphylococcal Infections
|
0.00%
0/7938
|
0.06%
5/7933
|
|
Infections and infestations
Vestibular Neuronitis
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Infections and infestations
Hepatitis B
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Infections and infestations
Influenza
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Infections and infestations
Pyelonephritis Acute
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Infections and infestations
Abdominal Abscess
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Infections and infestations
Bursitis Infective
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Infections and infestations
Device Related Infection
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Infections and infestations
Endocarditis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Infections and infestations
Escherichia Urinary Tract Infection
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Infections and infestations
Gastroenteritis Viral
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Infections and infestations
Hematoma Infection
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Infections and infestations
Helicobacter Gastritis
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Infections and infestations
Localized Injection
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Infections and infestations
Pharyngitis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Infections and infestations
Pneumonia Bacterial
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Infections and infestations
Pneumonia Primary Atypical
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Infections and infestations
Skin Infection
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Infections and infestations
Bacteraemia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Campylobacter Gastroenteritis
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Chronic Sinusitis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Clostridium Difficile Sepsis
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Cystitis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Diarrhea Infectious
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Enterocolitis Infectious
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Gastroenteritis Salmonella
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Groin Abscess
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Incision Site Infection
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Infected Skin Ulcer
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Joint Abscess
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Liver Abscess
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Otitis Media Chronic
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Perirectal Abscess
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Post Procedural Sepsis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Postoperative Wound Infection
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Pulmonary Sepsis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Scrotal Abscess
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Sialoadenitis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Infections and infestations
Staphylococcal Bacteraemia
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Infections and infestations
Tracheobronchitis
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Wound Abscess
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Wound Infection Staphylococcal
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Infections and infestations
Abdominal Sepsis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Abdominal Wall Abscess
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Abdominal Wall Infection
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Abscess Neck
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Acute Tonsillitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Appendiceal Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Arthritis Bacterial
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Arthritis Infective
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Aspergillosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Blister Infected
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Bronchitis Viral
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Campylobacter Infection
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Cellulitis of External Male Genital Organ
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Cellulitis Orbital
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Cellulitis Staphylococcus
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Clostridial Infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Clostridium Difficile Colitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Coccidioidomycosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Dengue Fever
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Diabetic Foot Infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Escherichia infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Escherichia Sepsis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Extradural Abscess
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Febrile Infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Gastric Ulcer Helicobacter
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Giardiasis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Haemophilus Infection
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Hepatitis A
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Herpes Zoster Ophthalmic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Infected Dermal Cyst
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Injection Site Cellulitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Klebsiella Sepsis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Laryngitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Lobar Pneumonia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Mediastinitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Meningitis Herpes
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Nasopharyngitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Parotid Abscess
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Peridiverticular Abscess
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Subcutaneous Abscess
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Infections and infestations
Tracheostomy Infection
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Infections and infestations
Viral Myocarditis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Non-Cardiac Chest Pain
|
1.8%
145/7938
|
1.9%
152/7933
|
|
General disorders
Chest Pain
|
1.2%
97/7938
|
1.3%
103/7933
|
|
General disorders
Chest Discomfort
|
0.15%
12/7938
|
0.18%
14/7933
|
|
General disorders
Pyrexia
|
0.04%
3/7938
|
0.05%
4/7933
|
|
General disorders
Asthenia
|
0.01%
1/7938
|
0.05%
4/7933
|
|
General disorders
Edema Peripheral
|
0.04%
3/7938
|
0.01%
1/7933
|
|
General disorders
Multi-Organ Failure
|
0.03%
2/7938
|
0.01%
1/7933
|
|
General disorders
Device Dislocation
|
0.01%
1/7938
|
0.01%
1/7933
|
|
General disorders
Device Malfunction
|
0.01%
1/7938
|
0.01%
1/7933
|
|
General disorders
Fatigue
|
0.01%
1/7938
|
0.01%
1/7933
|
|
General disorders
Malaise
|
0.00%
0/7938
|
0.03%
2/7933
|
|
General disorders
Pain
|
0.00%
0/7938
|
0.03%
2/7933
|
|
General disorders
Spinal Pain
|
0.01%
1/7938
|
0.01%
1/7933
|
|
General disorders
Catheter Site Hematoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Chronic Fatigue Syndrome
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Device Damage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Drug Intolerance
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Gait Disturbance
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
General Physical Health Deterioration
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Granuloma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Hernia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Hernia Obstructive
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Impaired Healing
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Implant Site Inflammation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Local Swelling
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Polyserositis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Pseudocyst
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Puncture Site Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Soft Tissue Inflammation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Vessel Puncture Site Hematoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Prostate Cancer
|
0.39%
31/7938
|
0.43%
34/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Cancer
|
0.10%
8/7938
|
0.19%
15/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Neoplasm Malignant
|
0.14%
11/7938
|
0.14%
11/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Colon Cancer
|
0.14%
11/7938
|
0.10%
8/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Gastric Cancer
|
0.06%
5/7938
|
0.14%
11/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Malignant Melanoma
|
0.10%
8/7938
|
0.10%
8/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Transitional Cell Carcinoma
|
0.09%
7/7938
|
0.08%
6/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Cancer Metastatic
|
0.10%
8/7938
|
0.06%
5/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Basal Cell Carcinoma
|
0.09%
7/7938
|
0.06%
5/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Breast Cancer
|
0.05%
4/7938
|
0.10%
8/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Renal Cell Carcinoma
|
0.06%
5/7938
|
0.09%
7/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Rectal Cancer
|
0.11%
9/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Cancer Recurrent
|
0.04%
3/7938
|
0.05%
4/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Laryngeal Cancer
|
0.05%
4/7938
|
0.04%
3/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Squamous Cell Carcinoma of Skin
|
0.03%
2/7938
|
0.06%
5/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Adenocarcinoma
|
0.03%
2/7938
|
0.05%
4/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Squamous Cell Carcinoma Stage Unspecified
|
0.05%
4/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Non-Small Cell Lung Cancer
|
0.06%
5/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Renal Cancer
|
0.03%
2/7938
|
0.05%
4/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
B-Cell Lymphoma
|
0.03%
2/7938
|
0.04%
3/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Lung Neoplasm
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Neoplasm of Thyroid Gland
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Chronic Lymphocytic Leukemia
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Colon Adenoma
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Colon Cancer Metastatic
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Meningioma
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Pancreatic Carcinoma
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Renal Cancer Metastatic
|
0.00%
0/7938
|
0.05%
4/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Small Cell Lung Cancer Stage Unspecified
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Acute Myeloid Leukemia
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bronchial Carcinoma
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lip And/Or Oral Cavity Cancer
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lipoma
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Adenocarcinoma Metastatic
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Multiple Myeloma
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Melodysplastic Syndrome
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Non-Hodgkins Lymphoma
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Esophageal Adenocarcinoma
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tongue Neoplasm Malignant Stage Unspecified
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Transitional Cell Carcinoma
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Acute Monocytic Leukemia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Adenocarcinoma
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Adenoma Benign
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Breast Cancer In Situ
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Breast Cancer Metastatic
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Breast Cancer Recurrent
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Malignant Melanoma In Situ
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Meningioma Benign
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastases To Bone
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastases To Central Nervous System
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastases To Liver
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metasteses To Peritoneum
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Bronchial Carcinoma
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Carcinoid Tumor
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Gastric Cancer
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Neoplasm
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Renal Cell Carcinoma
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Esophageal Cancer Metastatic
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Pancreatic Carcinoma Metastatic
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Parathyroid Tumor Benign
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Pituitary Tumor Benign
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Rectal Cancer Metastatic
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Squamous Cell Carcinoma
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Thyroid Cancer
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Uterine Leiomyoma
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Acute Leukemia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Adenocarcinoma Pancreas
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Adrenal Carcinoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Astrocytoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Basosquamous Carcinoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Breast Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Gastric Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Neoplasm
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Pancreatic Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Benign Salivary Gland Neoplasm
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Biliary Cancer Metastatic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Adenocarcinoma Stage Unspecified
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Papiloma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Squamous Cell Carcinoma Stage Unspecified
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bladder Transitional Cell Carcinoma Recurrent
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bone Neoplasm Malignant
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Bowen's Disease
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Burkit's Lymphoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Carcinoid Tumor Of The Gastrointestinal Tract
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Carcinoma Tumor Of The Small Bowel
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Cervix Carcinoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Cholesteatoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Chronic Leukemia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Chronic Myolomonocytic Leukemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Colon Cancer Stage II
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Colon Cancer Stage IV
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Colorectal Cancer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Endometrial Cancer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Ependymoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Extranodal Marginal Zone B-Cell Lymphoma (Malt Type)
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Gallbladder Cancer
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Gastrointestinal Cancer Metastatic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Gastrointestinal Stromal Tumor
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Glioblastoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Hemangioma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Hodgkin's Disease
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Inflammatory Pseudotumor
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Intraductal Papilloma Of Breast
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Keratoacanthoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Large Cell Lung Cancer Metastatic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Laryngeal Cancer Stage 0 Leiomyoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lentigo Maligna Stage Unspecified
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Adenocarcinoma Stage I
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Adenocarcinoma Stage IV
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Lung Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Malignant Fibrous Histiocytoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metasteses To Lung
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Malignant Melanoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Squamous Cell Carcinoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastatic Uterine Cancer Myelofibrosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Nasal Cavity Cancer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Neurilemmoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Esophageal Carcinoma Stage 0
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Osteochondroma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Ovarian Cancer Metastatic
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Ovarian Epithelial Cancer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Paget's Disease Of Skin
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Pancreatic Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Papilloma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Prostate Cancer Recurrent
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Prostatic Adenoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Rectosigmoid Cancer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Renal Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Sebaceous Carcinoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Skin Cancer
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Spindle Cell Sarcoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Thymoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Thymoma Malignant
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Thyroid Neoplasm
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tonsil Cancer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tumor Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tumor Perforation
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Uterine Cancer
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastrointestinal Hemorrhage
|
0.18%
14/7938
|
0.26%
21/7933
|
|
Gastrointestinal disorders
Inguinal Hernia
|
0.16%
13/7938
|
0.21%
17/7933
|
|
Gastrointestinal disorders
Abdominal Pain
|
0.14%
11/7938
|
0.19%
15/7933
|
|
Gastrointestinal disorders
Gastritis
|
0.10%
8/7938
|
0.13%
10/7933
|
|
Gastrointestinal disorders
Upper Gastrointestinal Hemorrhage
|
0.10%
8/7938
|
0.13%
10/7933
|
|
Gastrointestinal disorders
Abdominal Pain Upper
|
0.09%
7/7938
|
0.11%
9/7933
|
|
Gastrointestinal disorders
Gastroesophageal Reflux Disease
|
0.14%
11/7938
|
0.06%
5/7933
|
|
Gastrointestinal disorders
Small Intestinal Obstruction
|
0.14%
11/7938
|
0.06%
5/7933
|
|
Gastrointestinal disorders
Diarrhea
|
0.09%
7/7938
|
0.09%
7/7933
|
|
Gastrointestinal disorders
Pancreatitis
|
0.09%
7/7938
|
0.09%
7/7933
|
|
Gastrointestinal disorders
Pancreatitis Acute
|
0.10%
8/7938
|
0.08%
6/7933
|
|
Gastrointestinal disorders
Dyspepsia
|
0.09%
7/7938
|
0.08%
6/7933
|
|
Gastrointestinal disorders
Gastric Ulcer Hemorrhage
|
0.03%
2/7938
|
0.11%
9/7933
|
|
Gastrointestinal disorders
Colonic Polyp
|
0.05%
4/7938
|
0.08%
6/7933
|
|
Gastrointestinal disorders
Duodenal Ulcer Hemorrhage
|
0.08%
6/7938
|
0.05%
4/7933
|
|
Gastrointestinal disorders
Gastric Ulcer
|
0.06%
5/7938
|
0.06%
5/7933
|
|
Gastrointestinal disorders
Mallory-Weiss Syndrome
|
0.09%
7/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Constipation
|
0.04%
3/7938
|
0.05%
4/7933
|
|
Gastrointestinal disorders
Rectal Hemorrhage
|
0.08%
6/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Diverticular Perforation
|
0.01%
1/7938
|
0.05%
4/7933
|
|
Gastrointestinal disorders
Duodenal Ulcer
|
0.00%
0/7938
|
0.06%
5/7933
|
|
Gastrointestinal disorders
Gastric Hemorrhage
|
0.03%
2/7938
|
0.04%
3/7933
|
|
Gastrointestinal disorders
Ileus
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Lower Gastrointestinal Hemorrhage
|
0.05%
4/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Abdominal Discomfort
|
0.05%
4/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Colitis
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Diverticulum Intestinal Hemorrhagic
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Dysphagia
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Gastrointestinal disorders
Hematemesis
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Gastrointestinal disorders
Hemorrhoids
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Nausea
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Gastrointestinal disorders
Esophagitis
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Diverticulitis Intestinal Hemorrhagic
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Diverticulum
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Diverticulum Intestinal
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Food Poisoning
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Gastritis Erosive
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Gastritis Hemorrhagic
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Inguinal Hernia, Obstructive
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Esophageal Hemorrhage
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Umbilical Hernia
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Abdominal Hernia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Appendix Disorder
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Barrett's Esophagus
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Colitis Ischemic
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Colitis Ulcerative
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Crohn's Disease
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Duodenitis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastroduodenal Ulcer
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastroesophagitis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Hematochezia
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Hemorrhoidal Hemorrhage
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Intestinal Hemorrhage
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Intestinal Obstruction
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Intestinal Perforation
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Large Intestinal Ulcer Hemorrhage
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Large Intestine Perforation
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Melaena
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Esophageal Stenosis
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Esophageal Ulcer Hemorrhage
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Peptic Ulcer
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Gastrointestinal disorders
Peptic Ulcer Hemorrhage
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Vomiting
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Abdominal Distention
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Abdominal Hernia Obstructive
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Abdominal Pain Lower
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Abdominal Wall Hematoma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Acute Abdomen
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Anal Fissure
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Anal Fistula
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Colitis Microscopic
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Dental Caries
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Diaphragmatic Hernia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Enteritis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Enterocolitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Enterocolitis Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Eosinophilic Colitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Erosive Esophagitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Faecaloma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Gallstone Ileus
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Gastric Polyps
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastric Ulcer Perforation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastroduodenal Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Gastroduodenitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Gastrointestinal Disorder
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Gastrointestinal Inflammation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastrointestinal Ulcer Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Gastrointestinal Vascular Malformation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Hiatus Hernia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Ileitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Inguinal Hernia Strangulated
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Intestinal Hematoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Intestinal Ischemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Intestinal Polyp Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Intussusception
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Lip Edema
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Lip Swelling
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Megacolon
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Mouth Cyst
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Esophageal Food Impaction
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Esophageal Obstruction
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Esophageal Ulcer
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Esophagitis Ulcerative
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Pancreatic Cyst
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Pancreatic Pseudocyst
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Pancreatitis Chronic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Pancreatitis Hemorrhagic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Pancreatitis Necrotising
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Pancreatitis Relapsing
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Periodontitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Polyp Colorectal
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Retroperitoneal Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Subileus
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Tongue Cyst
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Gastrointestinal disorders
Umbilical Hernia, Obstructive
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Gastrointestinal disorders
Volvulus Of Small Bowel
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Syncope
|
0.66%
52/7938
|
0.84%
67/7933
|
|
Nervous system disorders
Transient Ischemic Attack
|
0.20%
16/7938
|
0.24%
19/7933
|
|
Nervous system disorders
Presyncope
|
0.16%
13/7938
|
0.10%
8/7933
|
|
Nervous system disorders
Dizziness
|
0.11%
9/7938
|
0.11%
9/7933
|
|
Nervous system disorders
Sciatica
|
0.09%
7/7938
|
0.10%
8/7933
|
|
Nervous system disorders
Headache
|
0.06%
5/7938
|
0.05%
4/7933
|
|
Nervous system disorders
Vertibrobasilar Insufficiency
|
0.06%
5/7938
|
0.04%
3/7933
|
|
Nervous system disorders
Loss Of Consciousness
|
0.05%
4/7938
|
0.03%
2/7933
|
|
Nervous system disorders
Paresthesia
|
0.06%
5/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Subarachnoid Hemorrhage
|
0.05%
4/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Convulsion
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Nervous system disorders
Amnesia
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Cerebral Hemorrhage
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Diabetic Neuropathy
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Nervous system disorders
Hypoesthesia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Lumbar Radiculopathy
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Migraine
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Nerve Root Lesion
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Nervous system disorders
Radial Nerve Palsy
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Viith Nerve Paralysis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Acute Disseminated Encephalomyelitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Altered State of Consciousness
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Amyotrophic Lateral Sclerosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Carotid Artery Stenosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Carotid Sinus Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Cauda Equina Syndrome
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Cerebral Arteriosclerosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Cerebral Artery Stenosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Cerebral Cyst
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Cerebrovascular Accident
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Cognitive Disorder
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Complex Partial Seizure
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Coordination Abnormal
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Dementia With Lewey Bodies
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Demyelinating Polyneuropathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Dizziness Exertional
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Dizziness Postural
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Epilepsy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Facial Paresis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Guillain-Barre Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Hemorrhage Intracranial
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Hemiparesis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Hypoglycemic Coma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Hypoglycemic Unconsciousness
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Intracranial Aneurysm
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Meningorrhagia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Metabolic Encephalopathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Motor Neuron Disease
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Multiple Sclerosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Multiple Sclerosis Relapse
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Myasthenia Gravis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Myelitis Transverse
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Nerve Root Compression
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Nervous System Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Neuritis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Neuropathy Peripheral
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Paraplegia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Psychomotor Hyperactivity
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Radicular Syndrome
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Ruptured Cerebral Aneurysm
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Senile Dementia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Speech Disorder
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Spinal Cord Compression
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Toxic Encephalopathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Transient Global Amnesia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Trigeminal Neuralgia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Nervous system disorders
Vertebral Artery Stenosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Nervous system disorders
Vertigo CNS Origin
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Osteoarthritis
|
0.39%
31/7938
|
0.40%
32/7933
|
|
Musculoskeletal and connective tissue disorders
Intervertebral Disk Protrusion
|
0.19%
15/7938
|
0.19%
15/7933
|
|
Musculoskeletal and connective tissue disorders
Musculoskeletal Chest Pain
|
0.25%
20/7938
|
0.08%
6/7933
|
|
Musculoskeletal and connective tissue disorders
Back Pain
|
0.10%
8/7938
|
0.15%
12/7933
|
|
Musculoskeletal and connective tissue disorders
Musculoskeletal Pain
|
0.09%
7/7938
|
0.08%
6/7933
|
|
Musculoskeletal and connective tissue disorders
Rotator Cuff Syndrome
|
0.06%
5/7938
|
0.09%
7/7933
|
|
Musculoskeletal and connective tissue disorders
Lumbar Spinal Stenosis
|
0.05%
4/7938
|
0.08%
6/7933
|
|
Musculoskeletal and connective tissue disorders
Arthralgia
|
0.04%
3/7938
|
0.06%
5/7933
|
|
Musculoskeletal and connective tissue disorders
Spinal Column Stenosis
|
0.03%
2/7938
|
0.08%
6/7933
|
|
Musculoskeletal and connective tissue disorders
Pain In Extremity
|
0.05%
4/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Arthritis
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Intervertebral Disk Disorder
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Musculoskeletal and connective tissue disorders
Rheumatoid Arthritis
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Musculoskeletal and connective tissue disorders
Spinal Osteoarthritis
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Arthropathy
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Bursitis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Neck Pain
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Rhabdomyolysis
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Bone Pain
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Costochondritis
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Fracture Nonunion
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Muscle Hemorrhage
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Muscular Weakness
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Myalgia
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Polymyalgia Rheumatica
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Musculoskeletal and connective tissue disorders
Psoriatic Arthropathy
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Spondylolisthesis
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Synovial Cyst
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Ankylosing Spondylitis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Bone Cyst
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Cervical Spinal Stenosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Chondrocalcinosis Pyrophosphate
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Dupuytren's Contracture
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Exostosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Fibromyalgia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Flank Pain
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Gouty Arthritis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Hemarthrosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Intervertebral Disc Degeneration
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Musculoskeletal Discomfort
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Myopathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Myositis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Nose Deformity
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Osteitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Osteochondritis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Osteochondrosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Osteoporosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Periarthritis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Polyarthritis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Pseudarthrosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Sensation Of Heaviness
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Spondyloarthropathy
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Musculoskeletal and connective tissue disorders
Tendon Calcification
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Musculoskeletal and connective tissue disorders
Ulnocarpal Abutment Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Ankle Fracture
|
0.14%
11/7938
|
0.08%
6/7933
|
|
Injury, poisoning and procedural complications
Hip Fracture
|
0.10%
8/7938
|
0.09%
7/7933
|
|
Injury, poisoning and procedural complications
Post Procedural Hemorrhage
|
0.10%
8/7938
|
0.06%
5/7933
|
|
Injury, poisoning and procedural complications
Head Injury
|
0.06%
5/7938
|
0.08%
6/7933
|
|
Injury, poisoning and procedural complications
Femur Fracture
|
0.09%
7/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Subdural Hematoma
|
0.04%
3/7938
|
0.08%
6/7933
|
|
Injury, poisoning and procedural complications
Fall
|
0.08%
6/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Foot Fracture
|
0.04%
3/7938
|
0.05%
4/7933
|
|
Injury, poisoning and procedural complications
Tibia Fracture
|
0.03%
2/7938
|
0.06%
5/7933
|
|
Injury, poisoning and procedural complications
Humerus Fracture
|
0.05%
4/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Lower Limb Fracture
|
0.03%
2/7938
|
0.05%
4/7933
|
|
Injury, poisoning and procedural complications
Incisional Hernia
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Lumbar Vertebral Fracture
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Laceration
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Meniscus Lesion
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Overdose
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Pneumothorax Traumatic
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Procedural Pain
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Injury, poisoning and procedural complications
Radius Fracture
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Tendon Rupture
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Injury, poisoning and procedural complications
Toxicity To Various Agents
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Injury, poisoning and procedural complications
Upper Limb Fracture
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Contusion
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Muscle Rupture
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Rib Fracture
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Road Traffic Accident
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Cervical Vertebral Fracture
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Clavicle Fracture
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Comminuted Fracture
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Concussion
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Extradural Hematoma
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Eye Injury
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Femoral Neck Fracture
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Fractured Sacrum
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Hand Fracture
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
In-Stent Coronary Artery Restenosis
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Multiple Fractures
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Pelvic Fracture
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Post Procedural Hematoma
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Postoperative Wound Complication
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Skull Fracture
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Spinal Compression Fracture
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Spinal Fracture
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Subdural Hemorrhage
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Thoracic Vertebral Fracture
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Traumatic Intracranial Hemorrhage
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Wound
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Wound Necrosis
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Injury, poisoning and procedural complications
Accident At Home
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Acetabulum Fracture
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Anemia Postoperative
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Animal Bite
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Back Injury
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Brain Contusion
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Cardiac Procedure Complication
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Cartilage Injury
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Chemical Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Complications Of Transplanted Heart
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Craniocerebral Injury
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Dislocation of Vertebra
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Electric Shock
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Eye Penetration
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Face Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Femoral Nerve Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Fibula Fracture
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Foreign Body
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Gastrointestinal Stoma Complication
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Incisional Hernia, Obstructive
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Injury Corneal
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Jaw Fracture
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Joint Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Limb Crushing Injury
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Limb Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Multiple Injuries
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Open Wound
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Post Procedural Complication
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Post Procedural Pulmonary Embolism
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Post Traumatic Pain
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Postoperative Thoracic Procedure Complication
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Procedural Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Procedural Hypotension
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Procedural Vomiting
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Scapula Fracture
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Seroma
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Skeletal Injury
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Skin Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Spinal Cord Injury
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Spinal Cord Injury Cervical
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Sternal Fracture
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Tendon Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Thermal Burn
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Traumatic Arthritis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Traumatic Arthropathy
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Traumatic Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Traumatic Liver Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Traumatic Renal Injury
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Injury, poisoning and procedural complications
Vascular Pseudoaneurism
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Injury, poisoning and procedural complications
Wound Secretion
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Chronic Pulmonary Obstructive Disease
|
0.34%
27/7938
|
0.26%
21/7933
|
|
Respiratory, thoracic and mediastinal disorders
Dyspnea
|
0.24%
19/7938
|
0.19%
15/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pulmonary Embolism
|
0.19%
15/7938
|
0.19%
15/7933
|
|
Respiratory, thoracic and mediastinal disorders
Epistaxis
|
0.19%
15/7938
|
0.14%
11/7933
|
|
Respiratory, thoracic and mediastinal disorders
Respiratory Failure
|
0.10%
8/7938
|
0.09%
7/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pleural Effusion
|
0.04%
3/7938
|
0.06%
5/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pulmonary Edema
|
0.04%
3/7938
|
0.06%
5/7933
|
|
Respiratory, thoracic and mediastinal disorders
Dyspnea Exertional
|
0.05%
4/7938
|
0.04%
3/7933
|
|
Respiratory, thoracic and mediastinal disorders
Acute Pulmonary Edema
|
0.03%
2/7938
|
0.05%
4/7933
|
|
Respiratory, thoracic and mediastinal disorders
Acute Respiratory Failure
|
0.01%
1/7938
|
0.06%
5/7933
|
|
Respiratory, thoracic and mediastinal disorders
Asthma
|
0.04%
3/7938
|
0.04%
3/7933
|
|
Respiratory, thoracic and mediastinal disorders
Hemoptysis
|
0.01%
1/7938
|
0.06%
5/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pneumothorax
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Respiratory, thoracic and mediastinal disorders
Bronchitis Chronic
|
0.00%
0/7938
|
0.05%
4/7933
|
|
Respiratory, thoracic and mediastinal disorders
Hyperventilation
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pleuritic Pain
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Respiratory Distress
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Respiratory, thoracic and mediastinal disorders
Emphysema
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Hemothorax
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Interstitial Lung Disease
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pulmonary Fibrosis
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Atelectasis
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Respiratory, thoracic and mediastinal disorders
Bronchospasm
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Nasal Septum Deviation
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pleurisy
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Sleep Apnea Syndrome
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Alveolitis Allergic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Chronic Respiratory Failure
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Cough
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Hydropneumothorax
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Hypoxia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Idiopathic Pulmonary Fibrosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Obstructive Airways Disorder
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Organising Pneumonia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Esophageal Swelling
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pickwickian Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pneumonia Aspiration
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pneumonitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pulmonary Hypertension
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Pulmonary Microemboli
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Respiratory, thoracic and mediastinal disorders
Stridor
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Hypertension
|
0.39%
31/7938
|
0.18%
14/7933
|
|
Vascular disorders
Hypotension
|
0.13%
10/7938
|
0.13%
10/7933
|
|
Vascular disorders
Deep Vein Thrombosis
|
0.14%
11/7938
|
0.10%
8/7933
|
|
Vascular disorders
Hypertensive Crisis
|
0.11%
9/7938
|
0.10%
8/7933
|
|
Vascular disorders
Orthostatic Hypotension
|
0.04%
3/7938
|
0.04%
3/7933
|
|
Vascular disorders
Peripheral Arterial Occlusive Disease
|
0.04%
3/7938
|
0.04%
3/7933
|
|
Vascular disorders
Accelerated Hypertension
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Vascular disorders
Hematoma
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Vascular disorders
Thrombophlebitis
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Vascular disorders
Aortic Aneurism
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Vascular disorders
Varicose Vein
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Vascular disorders
Thrombosis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Vascular disorders
Aortic Aneurism Rupture
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Aortic Atherosclerosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Arterial Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Arterial Rupture
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Arterial Thrombosis Limb
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Blood Pressure Inadequately Controlled
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Circulatory Collapse
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Diabetic Vascular Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Endothelial Dysfunction
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Femoral Arterial Stenosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Hyperemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Hypovolemic Shock
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Labile Hypertension
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Vascular disorders
Malignant Hypertension
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Popliteal Artery Entrapment
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Shock Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Venus Insufficiency
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Vascular disorders
Venus Thrombosis Limb
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Renal Failure Acute
|
0.21%
17/7938
|
0.24%
19/7933
|
|
Renal and urinary disorders
Nephrolithiasis
|
0.10%
8/7938
|
0.14%
11/7933
|
|
Renal and urinary disorders
Calculus Ureteric
|
0.08%
6/7938
|
0.08%
6/7933
|
|
Renal and urinary disorders
Renal Colic
|
0.05%
4/7938
|
0.10%
8/7933
|
|
Renal and urinary disorders
Renal Failure
|
0.09%
7/7938
|
0.06%
5/7933
|
|
Renal and urinary disorders
Hematuria
|
0.06%
5/7938
|
0.05%
4/7933
|
|
Renal and urinary disorders
Acute Prerenal Failure
|
0.03%
2/7938
|
0.06%
5/7933
|
|
Renal and urinary disorders
Renal Failure Chronic
|
0.03%
2/7938
|
0.03%
2/7933
|
|
Renal and urinary disorders
Urinary Retention
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Hydronephrosis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Renal and urinary disorders
Tubulointerstitial Nephritis
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Urethral Stenosis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Renal and urinary disorders
Calculus Bladder
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Hemorrhage Urinary Tract
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Postrenal Failure
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Renal and urinary disorders
Renal Hemorrhage
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Renal Impairment
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Renal and urinary disorders
Ureteric Stenosis
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Bladder Fibrosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Bladder Neck Obstruction
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Bladder Neck Stenosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Bladder Stenosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Calculus Urinary
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Nephrotic Syndrome
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Obstructive Uropathy
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Pelvic-Ureteric Obstruction
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Renal Mass
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Stag Horn Calculus
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Ureteric Obstructive
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Renal and urinary disorders
Urethral Pain
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Renal and urinary disorders
Urinary Incontinence
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Hepatobiliary disorders
Cholelithiasis
|
0.18%
14/7938
|
0.20%
16/7933
|
|
Hepatobiliary disorders
Cholecystitis Acute
|
0.13%
10/7938
|
0.18%
14/7933
|
|
Hepatobiliary disorders
Cholecystitis
|
0.10%
8/7938
|
0.13%
10/7933
|
|
Hepatobiliary disorders
Bile Duct Stone
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Hepatobiliary disorders
Cholangitis
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Hepatobiliary disorders
Hepatic Cirrhosis
|
0.05%
4/7938
|
0.00%
0/7933
|
|
Hepatobiliary disorders
Cholecystitis Chronic
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Hepatobiliary disorders
Biliary Colic
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Hepatobiliary disorders
Drug Induced Liver Injury
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Hepatobiliary disorders
Hepatitis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Hepatobiliary disorders
Hepatotoxicity
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Hepatobiliary disorders
Jaundice Cholestatic
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Hepatobiliary disorders
Porcelain Gallbladder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Hepatobiliary disorders
Portal Vein Thrombosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Diabetes Mellitus
|
0.08%
6/7938
|
0.10%
8/7933
|
|
Metabolism and nutrition disorders
Diabetes Mellitus Inadequate Control
|
0.05%
4/7938
|
0.11%
9/7933
|
|
Metabolism and nutrition disorders
Hypoglycemia
|
0.10%
8/7938
|
0.06%
5/7933
|
|
Metabolism and nutrition disorders
Dehydration
|
0.09%
7/7938
|
0.05%
4/7933
|
|
Metabolism and nutrition disorders
Hyperglycemia
|
0.05%
4/7938
|
0.05%
4/7933
|
|
Metabolism and nutrition disorders
Hyperkalemia
|
0.04%
3/7938
|
0.06%
5/7933
|
|
Metabolism and nutrition disorders
Type 2 Diabetes Mellitus
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Metabolism and nutrition disorders
Diabetic Ketoacidosis
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Hypokalemia
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Cachexia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Gout
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Metabolism and nutrition disorders
Hyponatremia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Decreased Appetite
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Diabetic Complication
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Hyperglycemic Hyperosmolar Nonketotic Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Metabolism and nutrition disorders
Hypertriglyceridemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Metabolic Acidosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Obesity
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Metabolism and nutrition disorders
Type 1 Diabetes Mellitus
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Depression
|
0.10%
8/7938
|
0.10%
8/7933
|
|
Psychiatric disorders
Anxiety
|
0.01%
1/7938
|
0.06%
5/7933
|
|
Psychiatric disorders
Confusional State
|
0.05%
4/7938
|
0.03%
2/7933
|
|
Psychiatric disorders
Major Depression
|
0.05%
4/7938
|
0.03%
2/7933
|
|
Psychiatric disorders
Suicide Attempt
|
0.01%
1/7938
|
0.06%
5/7933
|
|
Psychiatric disorders
Mental Status Change
|
0.03%
2/7938
|
0.04%
3/7933
|
|
Psychiatric disorders
Suicidal Ideation
|
0.01%
1/7938
|
0.04%
3/7933
|
|
Psychiatric disorders
Completed Suicide
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Psychiatric disorders
Personality Disorder
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Psychiatric disorders
Abnormal Behavior
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Adjustment Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Alcohol Abuse
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Psychiatric disorders
Alcohol Withdrawal Syndrome
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Psychiatric disorders
Anxiety Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Bipolar Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Bipolar I Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Delirium
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Delirium Tremens
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Psychiatric disorders
Depression Suicidal
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Psychiatric disorders
Disorientaion
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Panic Disorder With Agoraphobia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Panic Action
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Psychiatric disorders
Schizoaffective Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Psychiatric disorders
Schizophrenia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Anemia
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Blood and lymphatic system disorders
Coagulopathy
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Blood and lymphatic system disorders
Hemorrhagic Anemia
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Blood and lymphatic system disorders
Iron Deficiency Anemia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Leukopenia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Acquired Hemophilia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Anemia Hemolytic Autoimmune
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Deficiency Anemia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Blood and lymphatic system disorders
Febrile Neutropenia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Blood and lymphatic system disorders
Heparin-Induced Thrombocytopenia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Blood and lymphatic system disorders
Hypochromic Anemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Idiopathic Thrombocytopenic Purpura
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Blood and lymphatic system disorders
Leukocytosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Microcytic Anemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Neutropenia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Normochromic Normocytic Anemia
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Blood and lymphatic system disorders
Splenic Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Blood and lymphatic system disorders
Spontaneous Hemotoma
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Blood and lymphatic system disorders
Thrombocytopenia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Benign Prostatic Hyperplasia
|
0.11%
9/7938
|
0.10%
8/7933
|
|
Reproductive system and breast disorders
Prostatitis
|
0.04%
3/7938
|
0.03%
2/7933
|
|
Reproductive system and breast disorders
Epididymitis
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Metrorrhagia
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Reproductive system and breast disorders
Uterine Prolapse
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Reproductive system and breast disorders
Breast Disorder
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Breast Pain
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Cervical Polyp
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Erectile Disfunction
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Reproductive system and breast disorders
Menometrorrhagia
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Ovarian Cyst
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Ovarian Cyst Torsion
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Pelvic Floor Muscle Weakness
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Postmenopausal Hemorrhage
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Prostatic Obstruction
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Prostatism
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Prostatomegaly
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Reproductive system and breast disorders
Rectocele
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Spermatocele
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Reproductive system and breast disorders
Uterine Hemorrhage
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Reproductive system and breast disorders
Uterine Polyp
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Blood Creatine Phosphokinase Increased
|
0.00%
0/7938
|
0.04%
3/7933
|
|
Investigations
Arteriogram Coronary
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Investigations
Blood Pressure Increase
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Investigations
Cardiac Stress Test Abnormal
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Investigations
Ejection Fraction Decreased
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Investigations
Exercise Test Abnormal
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Investigations
International Normalized Ratio Increased
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Investigations
Blood Glucose Increased
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Investigations
Blood Pressure Abnormal
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Echocardiogram Abnormal
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Hemoglobin Decreased
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Hepatic Enzyme Increased
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Investigations
International Normalized Ratio Abnormal
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Investigations
Oxygen Saturation Decreased
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Pulse Absent
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Urine Output Increased
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Investigations
Weight Decreased
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Ear and labyrinth disorders
Vertigo
|
0.06%
5/7938
|
0.06%
5/7933
|
|
Ear and labyrinth disorders
Hypoacusis
|
0.03%
2/7938
|
0.01%
1/7933
|
|
Ear and labyrinth disorders
Vertigo Positional
|
0.00%
0/7938
|
0.04%
3/7933
|
|
Ear and labyrinth disorders
Deafness Unilateral
|
0.03%
2/7938
|
0.00%
0/7933
|
|
Ear and labyrinth disorders
Tinnitus
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Ear and labyrinth disorders
Meniere's Disease
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Ear and labyrinth disorders
Sudden Loss Of Hearing
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Ear and labyrinth disorders
Tympanic Membrane Perforation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Ear and labyrinth disorders
Vestibular Disorder
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Skin and subcutaneous tissue disorders
Leukocytoclastic Vasculitis
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Skin and subcutaneous tissue disorders
Skin Ulcer
|
0.04%
3/7938
|
0.00%
0/7933
|
|
Skin and subcutaneous tissue disorders
Angioedema
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Skin and subcutaneous tissue disorders
Diabetic Foot
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Skin and subcutaneous tissue disorders
Rash
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Skin and subcutaneous tissue disorders
Actinic Keratosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Skin and subcutaneous tissue disorders
Decubitus Ulcer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Skin and subcutaneous tissue disorders
Dermatitis Allergic
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Skin and subcutaneous tissue disorders
Dermatitis Bulbous
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Skin and subcutaneous tissue disorders
Digital Ulcer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Skin and subcutaneous tissue disorders
Eczema
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Skin and subcutaneous tissue disorders
Hyperhidrosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Skin and subcutaneous tissue disorders
Ingrowing Nails
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Skin and subcutaneous tissue disorders
Lentigo
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Skin and subcutaneous tissue disorders
Neuropathic Ulcer
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Immune system disorders
Hypersensitivity
|
0.01%
1/7938
|
0.05%
4/7933
|
|
Immune system disorders
Anaphylactic Shock
|
0.04%
3/7938
|
0.01%
1/7933
|
|
Immune system disorders
Anaphylactic Reaction
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Immune system disorders
Antiphospholipid Syndrome
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Immune system disorders
Drug Hypersensitivity
|
0.01%
1/7938
|
0.01%
1/7933
|
|
Immune system disorders
Allergy For Arthropod Bite
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Immune system disorders
Amyloidosis
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Immune system disorders
Multiple Allergies
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Immune system disorders
Sarcoidosis
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Immune system disorders
Hydrocele
|
0.00%
0/7938
|
0.03%
2/7933
|
|
Congenital, familial and genetic disorders
Arteriovenous Malformation
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Congenital, familial and genetic disorders
Atrial Septal Defect
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Congenital, familial and genetic disorders
Gastrointestinal Arteriovenous Malformation
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Congenital, familial and genetic disorders
Hemorrhagic Arteriovenous Malformation
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Congenital, familial and genetic disorders
Keratosis Folicular
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Congenital, familial and genetic disorders
Laryngocele
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Endocrine disorders
Hyperthyroidism
|
0.01%
1/7938
|
0.03%
2/7933
|
|
Endocrine disorders
Hypercalcemia of Malignancy
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Congenital, familial and genetic disorders
Hyperparathyroidism
|
0.00%
0/7938
|
0.01%
1/7933
|
|
Endocrine disorders
Hypopituitarism
|
0.01%
1/7938
|
0.00%
0/7933
|
|
Endocrine disorders
Hypothyroidism
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Carcinoma Basocellular (Noze)
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Contusion Left Knee
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Dislodgment Of Gastronomy Tube
|
0.01%
1/7938
|
0.00%
0/7933
|
|
General disorders
Gastrointestinal Stomal Tumor
|
0.00%
0/7938
|
0.01%
1/7933
|
|
General disorders
Sigmoid Colon Adenocarcinoma
|
0.01%
1/7938
|
0.00%
0/7933
|
Other adverse events
| Measure |
Dalcetrapib (RO4607381)
n=7938 participants at risk
Dalcetrapib (RO4607381): 600mg po daily
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
|
Placebo
n=7933 participants at risk
Evidence-based medical care for Acute Coronary Syndrome: As prescribed
Placebo: po daily
|
|---|---|---|
|
Infections and infestations
Nasopharyngitis
|
5.5%
438/7938
|
5.8%
460/7933
|
|
General disorders
Chest Pain
|
10.5%
833/7938
|
10.5%
830/7933
|
|
General disorders
Fatigue
|
5.0%
396/7938
|
5.2%
416/7933
|
|
General disorders
Edema Peripheral
|
3.8%
300/7938
|
5.0%
393/7933
|
|
Gastrointestinal disorders
Diarrhea
|
6.8%
541/7938
|
4.3%
342/7933
|
|
Cardiac disorders
Angina Pectoris
|
7.4%
585/7938
|
7.2%
569/7933
|
|
Respiratory, thoracic and mediastinal disorders
Cough
|
5.1%
403/7938
|
5.2%
415/7933
|
|
Nervous system disorders
Dizziness
|
5.2%
413/7938
|
5.8%
459/7933
|
|
Vascular disorders
Hypertension
|
7.3%
578/7938
|
6.5%
513/7933
|
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place