REFORM Clinical Study: Treatment of Renal Artery Stenosis With the Formula Balloon-Expandable Stent

NCT ID: NCT00631540

Last Updated: 2013-12-16

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2012-05-31

Brief Summary

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The purpose of the study is to evaluate the safety and effectiveness of the Formula Balloon-Expandable Stent in treatment of renal artery stenosis.

Detailed Description

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Conditions

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Renal Artery Stenosis

Keywords

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renal artery stenosis hypertension renovascular renal artery blockage renal artery disease renal arteries angioplasty renal artery renal artery stent renal artery doppler renovascular hypertension kidney stenosis renal artery stent stenting kidney disease renal failure atherosclerosis arterial hypertension stenosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

renal artery stenting

Group Type EXPERIMENTAL

Formula Balloon-Expandable Stent

Intervention Type DEVICE

renal artery stenting

Interventions

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Formula Balloon-Expandable Stent

renal artery stenting

Intervention Type DEVICE

Other Intervention Names

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renal artery revascularization

Eligibility Criteria

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Inclusion Criteria

* renal artery stenosis
* appropriate size and location of the lesion
* suboptimal angioplasty

Exclusion Criteria

* less than 18 years old
* failure or inability to give informed consent
* simultaneously participating in another drug or device study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cook Group Incorporated

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Bersin, MD

Role: PRINCIPAL_INVESTIGATOR

Swedish Medical Center

Locations

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Munroe Regional Medical Center

Ocala, Florida, United States

Site Status

Orlando Regional Medical Center

Orlando, Florida, United States

Site Status

Lenox Hill Hospital

New York, New York, United States

Site Status

Wake Med Raleigh Campus

Raleigh, North Carolina, United States

Site Status

Fairfield Medical Center

Lancaster, Ohio, United States

Site Status

Pinnacle Health at Harrisburg

Harrisburg, Pennsylvania, United States

Site Status

Swedish Medical Center

Seattle, Washington, United States

Site Status

Countries

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United States

References

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Bersin RM, Ansel G, Rizzo A, Bob Smouse H, Sinha S, Sachar R, Dave R, Weinstock BS, Feldman R, Roubin GS. Nine-month results of the REFORM study: a prospective, single-arm, multicenter clinical study of the safety and effectiveness of the Formula balloon-expandable stent for treatment of renal artery stenosis. Catheter Cardiovasc Interv. 2013 Aug 1;82(2):266-73. doi: 10.1002/ccd.24481. Epub 2013 Mar 25.

Reference Type DERIVED
PMID: 22581488 (View on PubMed)

Other Identifiers

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FRUS

Identifier Type: -

Identifier Source: secondary_id

06-581

Identifier Type: -

Identifier Source: org_study_id