Cook Enforcer Post-Market Study

NCT ID: NCT03552289

Last Updated: 2020-10-19

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

211 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-07

Study Completion Date

2019-08-27

Brief Summary

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The purpose of this study is to evaluate the performance of the Cook Advance® Enforcer™ 35 Focal-Force PTA Balloon Catheter (or Enforcer balloon) in treating narrowed blood vessels compared to treatment with a conventional angioplasty balloon.

Detailed Description

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Conditions

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End-Stage Renal Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Cook Enforcer balloon catheter

The Enforcer balloon will be used in the treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistula.

Group Type ACTIVE_COMPARATOR

Cook Advance® Enforcer 35 Focal-Force Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter

Intervention Type DEVICE

The Enforcer balloon device will be used in treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistula

Conventional angioplasty balloon catheters

Commercially available angioplasty balloon devices will be used in the treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistula.

Group Type ACTIVE_COMPARATOR

Conventional angioplasty balloon catheters

Intervention Type DEVICE

Commercially available angioplasty balloon devices will be used in treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistula

Interventions

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Cook Advance® Enforcer 35 Focal-Force Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter

The Enforcer balloon device will be used in treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistula

Intervention Type DEVICE

Conventional angioplasty balloon catheters

Commercially available angioplasty balloon devices will be used in treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistula

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Clinical or physiological abnormalities which indicate dialysis access dysfunction (e.g., decreased access blood flow, elevated venous pressure, decreased dialysis dose, abnormal physical exam)

Exclusion Criteria

* Less than 18 years old
* Pregnant, lactating, or planning to become pregnant in the 3 months following enrollment
* Underwent any surgical or interventional procedure of the access circuit less than or equal to 30 days prior to enrollment
* Scheduled for a kidney transplant
* Stent or stent graft in the arteriovenous (AV) dialysis access circuit
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cook Research Incorporated

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Arizona Kideny Disease & Hypertension Surgery Center

Phoenix, Arizona, United States

Site Status

The Vascular Experts

Darien, Connecticut, United States

Site Status

Delaware Kidney/Nephrology Associates, PA

Newark, Delaware, United States

Site Status

Fairlawn Surgery Center

Roanoke, Virginia, United States

Site Status

Vascular Institute of Virginia

Woodbridge, Virginia, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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17-04

Identifier Type: -

Identifier Source: org_study_id

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