Labor Analgesia With Ropivacaine and Clonidine

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-05-31

Study Completion Date

2001-12-31

Brief Summary

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The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

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Detailed Description

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Conditions

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Labor Pain

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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R

R group:15 mL of 0.125% ropivacaine (18.75 mg)

ropivacaine

Intervention Type DRUG

15 ml of ropivacaine 0.125% peridural once

RC

RC group:0.0625% ropivacaine (9.375 mg) plus 75 ug clonidine

ropivacaine and clonidine

Intervention Type DRUG

15 ml of ropivacaine 0.0625% plus 75 mcg clonidine

Interventions

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ropivacaine

15 ml of ropivacaine 0.125% peridural once

Intervention Type DRUG

ropivacaine and clonidine

15 ml of ropivacaine 0.0625% plus 75 mcg clonidine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Singleton healthy
* Full-term pregnancy
* American Society of Anesthesiologists physical status I or II

Exclusion Criteria

* Patients who had received opioids
* History of hypersensitivity to local anesthetic or to clonidine
* Fetus showed signs of possible intrauterine suffering
* Fetus showed signs of possible neurological deficit

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes