Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
260 participants
INTERVENTIONAL
1996-12-31
2029-12-31
Brief Summary
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Detailed Description
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This is not a clinical trial in the classical sense, but an omnibus protocol to allow for disntinct and personalized pathophysiological testing.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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Patients
Patients with orthostatic intolerance
DAXOR
131-I-Human Serum Albumin Blood Volume Assessment Kit
QSweat
Quantitative Sweat Testing
Intrinsic Heart Rate
Atropine 0.04 mg/kg IV in divided doses Propranolol 0.2 mg/kg IV in divided doses
Healthy Control Subjects
Healthy subjects to determine "normal" response
DAXOR
131-I-Human Serum Albumin Blood Volume Assessment Kit
QSweat
Quantitative Sweat Testing
Intrinsic Heart Rate
Atropine 0.04 mg/kg IV in divided doses Propranolol 0.2 mg/kg IV in divided doses
Interventions
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DAXOR
131-I-Human Serum Albumin Blood Volume Assessment Kit
QSweat
Quantitative Sweat Testing
Intrinsic Heart Rate
Atropine 0.04 mg/kg IV in divided doses Propranolol 0.2 mg/kg IV in divided doses
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
80 Years
ALL
Yes
Sponsors
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Satish R. Raj
OTHER
Responsible Party
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Satish R. Raj
Assistant Professor of Medicine & Pharmacology
Principal Investigators
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David Robertson, MD
Role: PRINCIPAL_INVESTIGATOR
Vanderbilt University
Locations
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Vanderbilt University
Nashville, Tennessee, United States
Countries
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References
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Mustafa HI, Garland EM, Biaggioni I, Black BK, Dupont WD, Robertson D, Raj SR. Abnormalities of angiotensin regulation in postural tachycardia syndrome. Heart Rhythm. 2011 Mar;8(3):422-8. doi: 10.1016/j.hrthm.2010.11.009. Epub 2011 Jan 22.
Related Links
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Website of the Vanderbilt Autonomic Dysfunction Center
Other Identifiers
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8398
Identifier Type: -
Identifier Source: org_study_id
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