Chronic Obstructive Pulmonary Disease Markers and Prognosis

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

133 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2012-02-29

Brief Summary

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The study aim is to verify the association between the changes in markers of disease and patient´s prognosis in chronic obstructive pulmonary disease.

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Detailed Description

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In a previous study, 133 COPD patients were followed-up during the period of one-year. Analyses of the association between baseline characteristic and the occurence of disease exacerbation was performed. In this study, the patients included in the previous research will be contacted and invited to participate in a complete evaluation after a three-year period. The association of the changes in dyspnea perception, spirometry variables, body composition, quality of life and exercise tolerance measures with disease prognostic will be studied.

Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Study COPD population

Patients with diagnosis of mild to very severe chronic obstructive pulmonary disease

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* COPD diagnosis according to the GOLD criteria

Exclusion Criteria

* Asthma
* Inability to perform pulmonary function and exercise tolerance tests
* Recent myocardial infarction or unstable angina
* Congestive heart failure: class III/IV

Minimum Eligible Age

40 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No