Language Function in Patients With Brain Tumors

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

7 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-05-31

Study Completion Date

2009-03-31

Brief Summary

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The purpose of this study is to use an imaging method called functional magnetic resonance imaging (fMRI) in patients who have a tumor near an area of the brain that is believed to control language. The fMRI is a new kind of imaging that uses a strong magnetic field to look at functioning brain tissue. This kind of imaging will be used to study the effect of the brain tumor on your speech.

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Detailed Description

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Conditions

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Brain Cancer CNS Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

neurosurgical patients

fMRI Scan, pre- and post language evaluation

Intervention Type OTHER

All subjects will undergo functional MR imaging, pre- and post-surgical language evaluation, and electrocortical stimulation mapping. The brain tumor patients will undergo these procedures twice.

Interventions

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fMRI Scan, pre- and post language evaluation

All subjects will undergo functional MR imaging, pre- and post-surgical language evaluation, and electrocortical stimulation mapping. The brain tumor patients will undergo these procedures twice.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.
* At least 18 years of age
* English as first language

Exclusion Criteria

* Patients with high grade tumors
* History of significant psychiatric condition (e.g. schizophrenia, obsessive-compulsive disorder, significant dementia),
* History of the following neurological conditions: CVA, demyelinating conditions, cerebral palsy, Alzheimer's disease.
* History of significant claustrophobic reactions.
* Pregnancy
* Standard contraindications to MR examinations (e.g. implanted stimulator)
* Patients, who were treated prior to our first scan, will not be eligible to participate in this study

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No