Quality Of Life Outcomes Following Treatment for Esophageal Cancer

NCT ID: NCT00598117

Last Updated: 2013-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

409 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-08-31

Study Completion Date

2013-06-30

Brief Summary

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The goal of this study is to evaluate how treatment for esophageal cancer affects your quality of life. The findings of this study may help us understand how this disease and its treatment affect your lifestyle, diet, exercise, support system and overall quality of life. We hope this study will provide important information that can be used to develop programs to improve the quality of life of patients with esophageal cancer.

Detailed Description

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In order to determine the impact of esophageal cancer and its treatment on patients' quality of life over time, this study will prospectively follow a cohort of patients at specified intervals, evaluating their physical symptoms, physical and social functioning and overall quality of life. Medical and sociodemographic factors as well as health behaviors that might be predictive of adaptation will be tested. This is a preliminary investigation and it is hoped that we will be able to base future research questions on the results of this study.

Conditions

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Esophageal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Group 1 (newly diagnosed patients) Initial assessment → first post op visit → 6 and 12 months post surgery

Questionnaires

Intervention Type BEHAVIORAL

Newly diagnosed patients will be assessed at four points Time 1 (prior to treatment)

* Initial QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS, Time 2 (initial post-op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS Time 3 (6 months post op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS, Time 4 (1 year post op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS

2

Group 2 (post-treatment patients) A one-time assessment will be conducted at least 18 months following treatment

Questionnaires

Intervention Type BEHAVIORAL

Newly diagnosed patients will be assessed at four points Time 1 (prior to treatment)

* Initial QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS, Time 2 (initial post-op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS Time 3 (6 months post op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS, Time 4 (1 year post op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS

Interventions

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Questionnaires

Newly diagnosed patients will be assessed at four points Time 1 (prior to treatment)

* Initial QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS, Time 2 (initial post-op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS Time 3 (6 months post op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS, Time 4 (1 year post op)
* Follow up QOL form
* FACT-E, PAR, Symptom Assessment Scale, MDSS

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age 18 or older
* Diagnosis of esophageal cancer.
* Anticipated to undergo surgical resection (Ivor Lewis, Trans Hiatal, McKeown procedure) of esophageal cancer. (Group 1 patients only)
* Underwent esophagectomy for esophageal cancer at least 18 months prior to consent, with no evidence of disease. (Group 2 patients only)
* Ability to speak, read and write English.

Exclusion Criteria

* Inability to give informed consent.
* Patients anticipated to require a laryngectomy as part of their surgical resection.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Memorial Sloan Kettering Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Manjit Bains, MD

Role: PRINCIPAL_INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Locations

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Memorial Sloan Kettering Cancer Center

New York, New York, United States

Site Status

Countries

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United States

Related Links

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http://www.mskcc.org

Memorial Sloan-Kettering Cancer Center

Other Identifiers

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03-083

Identifier Type: -

Identifier Source: org_study_id

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