Evaluation of Kidney Disease in Liver Transplant Recipients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2006-09-30

Study Completion Date

2009-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A non-invasive urinary test that detects kidney injuries in liver transplant (LT) candidates would be useful for monitoring of kidney damage. Particularly, the ability to predict irreversibility of such renal damage or progressive nature of renal disease in LT candidates would be of importance to determine the need for dual kidney-liver transplantation (KLT) versus LT alone. We will correlate kidney histology with cytokine/chemokine profile expression in the urine as a potentially useful noninvasive diagnostic tool.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

New Urine and Blood Markers for Acute Kidney Injury in Liver Transplant Patients

NCT00855127

Renal Insufficiency, Acute

WITHDRAWN

Prospective Study of Urinary Markers of Fibrosis in Kidney Transplants

NCT01982903

Kidney Failure

UNKNOWN

Prediction of Acute Rejection in Renal Transplant

NCT00205257

Kidney Transplant

COMPLETED

The Study of Long-term Deterioration of Kidney Transplants.

NCT00217126

Kidney Transplant

COMPLETED

The Role of Biomarkers in the Early Detection of Acute Kidney Injury Induced by Liver Transplantation

NCT01333319

Acute Kidney Injury

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Kidney Disease Liver Transplantation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1

ESLD subjects on active liver transplant waiting list

No interventions assigned to this group

2

Subjects post-liver transplant with good liver function

No interventions assigned to this group

3

Subjects without liver disease undergoing kidney biopsy for diagnostic purposes

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Subjects on the liver transplant wait list, subjects who have received a liver transplant at least 6 months prior to enrollment, or subjects who have normal liver function and are about to undergo kidney biospy for diagnostic purposes.