Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

NCT ID: NCT00585858

Last Updated: 2016-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

15 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-09-30

Study Completion Date

2008-06-30

Brief Summary

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The purpose of this pilot study is to determine if there is clinical correlation between the CKT and transplant recipients who are known to be on minimal or no immunosuppression (presumed tolerant) and those who are on conventional amounts of immunosuppression and have either experienced rejection (presumed hyper-responsive to donor) or have not experienced rejection (unknown responsive state).

Detailed Description

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Conditions

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Kidney Transplantation Liver Transplantation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Subjects on mimimal or no immunosuppression and no rejection history

No interventions assigned to this group

2

Subjects who have had rejection on conventional immunosuppression

No interventions assigned to this group

3

Subjects who have not had acute or chronic rejection who are on conventional immunosuppression

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Kidney or liver transplant recipients for whom donor cells are available

Exclusion Criteria

* HcT \<32%
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Wisconsin, Madison

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Wisconsin

Madison, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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H-2006-0437

Identifier Type: -

Identifier Source: org_study_id

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