Oral Water Ingestion in Heart Transplant Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Study Completion Date

2029-12-31

Brief Summary

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In this study the investigators propose to assess the hemodynamic response to the ingestion of 16 fl oz of water. The investigators will test the hypothesis that water ingestion will increase the systemic vascular resistance.

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Detailed Description

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In this study we propose to assess the hemodynamic response to the ingestion of 16 fl oz of water. We will test the hypothesis that water ingestion will increase the systemic vascular resistance. This study will occur in patients status post cardiac transplantation during their clinical right heart catheterizations. Invasive hemodynamics including cardiac outputs and plasma norepinephrine levels will be measured before and 30 min after the water ingestion.

Conditions

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Blood Pressure Cardiac Transplantation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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1

water ingestion (16 fl oz within 3 minutes)

Group Type EXPERIMENTAL

water

Intervention Type DIETARY_SUPPLEMENT

water 500 ml x 1

Interventions

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water

water 500 ml x 1

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* s/p cardiac transplantation scheduled for clinical right heart catheterization
* age \> 18 years

Exclusion Criteria

* significant tricuspid regurgitation
* inability to safely swallow 500 ml of water
* other major medical comorbidities such as advanced renal disease where water ingestion may be harmful to patient

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No