Use of Diffuse Optical Spectroscopy for Evaluation of the Trauma/Critically Care Patients

NCT ID: NCT00581295

Last Updated: 2022-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

93 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-03-31

Study Completion Date

2011-04-30

Brief Summary

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Trauma remains the leading cause of death and disability for Americans age 1-44. Trauma can cause internal bleeding, and this bleeding is often hard to detect without sophisticate tests that take time to complete and analyze.

In addition, internal bleeding, including bleeding into the lung and chest cavity, as well as other blood loss, happens in many critically ill patients. For example, for hemorrhage, it is very difficult to detect active hemorrhage and to determine optimal rates of fluid and blood resuscitation.

Diffuse optical spectroscopy has the potential to accurately assess adequacy of tissue perfusion, oxygenation, tissue oxygen extraction, and cytochrome oxidation states that may be critical to optimal treatment, end- organ preservation, and survival.

Detailed Description

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The research' want to monitor tissue perfusion and indicators of tissue damage and viability in critically ill patients by using DOS.

Non-invasive Optical Techniques DOS,near-infrared diffuse optical spectroscopy (NIR-DOS.

NIR-DOS provides functional physiologic tissue/organ information without ionizing radiation and without withdrawing any blood, in a cost-effective and rapid manner. The application of frequency-domain photon migration analysis (FDPM) to NIRS allows independent measurements of tissue absorption and scattering properties at depths of 1 cm or more below the skin surface.

Such capabilities will improve early diagnosis, detection, optimization of therapy, assessment of adequacy of resuscitation, and alteration in management plans for all of these critical conditions.

Conditions

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Trauma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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trauma

Diffuse optical spectroscopy measurment

Diffuse optical spectroscopy

Intervention Type DEVICE

Diffuse optical spectroscopy measurment

Interventions

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Diffuse optical spectroscopy

Diffuse optical spectroscopy measurment

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult age 18 years or older, male or female
* Trauma/Critical Care patient

Exclusion Criteria

* Subject is not Trauma/Critical Care patient
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beckman Laser Institute University of California Irvine

OTHER

Sponsor Role collaborator

University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Beckman Laser Institute and Medical Center

Michael E. Lekawa, MD Chief, Division of Trauma/Critical Care Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Michael E Lekawa, M.D

Role: PRINCIPAL_INVESTIGATOR

Beckman Laser Institute

Locations

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Beckman Laser Institute,University of California, Irvine

Irvine, California, United States

Site Status

Trauma/Critical Care Units, UCI Medical Center

Orange, California, United States

Site Status

Countries

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United States

Other Identifiers

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20139435

Identifier Type: -

Identifier Source: org_study_id

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